Title: Cheap flights from Buffalo to Mayagüez ( BUF - MAZ) - Expedia.com ![Plaza Colon](https://images.trvl-media.com/place/6081861/cc88611b-0380-4d73-8e29-c6e6f7fe0193.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6081861/cc88611b-0380-4d73-8e29-c6e6f7fe0193.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $254 Cheap Flights from Buffalo (BUF) to Mayagüez (MAZ) [View $254 flight on Mon, Apr 13, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:253.40&airProductToken=AQqQAQowCMGCARIENDY1MBiBLSDvWSi8nIoDMJSdigM4UUAAWAFqBE1BSU5yCFFOTjJBSE0xCjEIwYIBEgQyODUxGO9ZILKiASiOnooDMPqfigM4UUABWAFqBE1BSU5yCFFOTjJBSE0xCikIuZYBEgI0MRiyogEgjMgBKMGiigMw86KKAzhTQAFYAWoCRVJyA1NJUBIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAE) ## Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Mayagüez (MAZ-Eugenio María de Hostos) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways [](https://www.expedia.com/Flights-Search?leg1=from:BUF,to:MAZ,departure:3/29/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) ## Cheap Flights from Buffalo to Mayagüez (BUF-MAZ) Prices were available within the past 7 days and start at $254 for one-way flights and $522 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![JetBlue Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/b6.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $522 Roundtrip found 16 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:521.90&airProductToken=AQppCi0IwmwSAzYzNRiBLSCyogEovp2KAzCpn4oDOFBAAFgBagJBTnIIUEk0UVJFWTUKOAjCbBIENTM3MRiyogEgjMgBKKmhigMw26GKAzhaQAFYAWoCQU5yBlpIMEJFTnoJCLmWARIDMDQwCmkKOAjCbBIENTM3MhiMyAEgsqIBKPTOigMwqM-KAzhaQABYAWoCQU5yBlpIMEJFTnoJCLmWARIDMDQxCi0IwmwSAzYzNBiyogEggS0o5s-KAzCH0ooDOFBAAVgBagJBTnIIUEk0UVJFWTUSCggBEAEYASoCQjYYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $525 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:524.90&airProductToken=AQqQAQowCMGCARIENDY1MBiBLSDvWSi8nIoDMJSdigM4UUAAWAFqBE1BSU5yCFFOTjJBSE0xCjEIwYIBEgQyODUxGO9ZILKiASiOnooDMPqfigM4UUABWAFqBE1BSU5yCFFOTjJBSE0xCikIuZYBEgI0MRiyogEgjMgBKMGiigMw86KKAzhTQAFYAWoCRVJyA1NJUBIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAE) ![JetBlue Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/b6.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $532 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:531.90&airProductToken=AQppCi0IwmwSAzYzNRiBLSCyogEovp2KAzCpn4oDOFBAAFgBagJBTnIIUEk0UVJFWTUKOAjCbBIENTM3MRiyogEgjMgBKKmhigMw26GKAzhNQAFYAWoCQU5yBk1IMEJFTnoJCLmWARIDMDQwCmkKOAjCbBIENTM3MBiMyAEgsqIBKO_LigMwo8yKAzhaQABYAWoCQU5yBlpIMEJFTnoJCLmWARIDMDM4Ci0IwmwSAzYzNBiyogEggS0o5s-KAzCH0ooDOFBAAVgBagJBTnIIUEk0UVJFWTUSCggBEAEYASoCQjYYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $535 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:534.90&airProductToken=AQqQAQowCMGCARIENDY1MBiBLSDvWSi8nIoDMJSdigM4UUAAWAFqBE1BSU5yCFFOTjJBSE0xCjEIwYIBEgQyODUxGO9ZILKiASiOnooDMPqfigM4UUABWAFqBE1BSU5yCFFOTjJBSE0xCikIuZYBEgI0MBiyogEgjMgBKKmhigMw26GKAzhLQAFYAWoCRVJyA0tJUBIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAE) ![JetBlue Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/b6.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $542 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:541.90&airProductToken=AQppCi0IwmwSAzYzNRiBLSCyogEovp2KAzCpn4oDOFBAAFgBagJBTnIIUEk0UVJFWTUKOAjCbBIENTM3MRiyogEgjMgBKKmhigMw26GKAzhNQAFYAWoCQU5yBk1IMEJFTnoJCLmWARIDMDQwCmkKOAjCbBIENTM3MRiMyAEgsqIBKK_NigMw482KAzhNQABYAWoCQU5yBk1IMEJFTnoJCLmWARIDMDQwCi0IwmwSAzYzNBiyogEggS0o5s-KAzCH0ooDOFBAAVgBagJBTnIIUEk0UVJFWTUSCggBEAEYASoCQjYYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $580 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:579.90&airProductToken=AQqSAQoxCMGCARIEMTIwNBiBLSDimgEo-JyKAzD0nYoDOE5AAFgBagRNQUlOcghOTk4yQUhNMQoyCMGCARIEMjIxOBjimgEgsqIBKNafigMwt6GKAzhOQAFYAWoETUFJTnIITk5OMkFITTEKKQi5lgESAjQxGLKiASCMyAEowaKKAzDzoooDOFNAAVgBagJFUnIDU0lQEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwAQ) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $591 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:590.90&airProductToken=AQqcAQo2CMSYARIEMjg5OBiBLSDjtAEo_ZyKAzDHnYoDOFVAAFgBaglNQUlOQ0xBU0NyCFVOWEwwU01ZCjcIxJgBEgQxOTEzGOO0ASCyogEok56KAzCUoIoDOFVAAVgBaglNQUlOQ0xBU0NyCFVOWEwwU01ZCikIuZYBEgI0MRiyogEgjMgBKMGiigMw86KKAzhTQAFYAWoCRVJyA1NJUBIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $601 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:600.90&airProductToken=AQqcAQo2CMSYARIEMjg5OBiBLSDjtAEo_ZyKAzDHnYoDOFVAAFgBaglNQUlOQ0xBU0NyCFVOWEwwU01ZCjcIxJgBEgQxOTEzGOO0ASCyogEok56KAzCUoIoDOFVAAVgBaglNQUlOQ0xBU0NyCFVOWEwwU01ZCikIuZYBEgI0MBiyogEgjMgBKKmhigMw26GKAzhLQAFYAWoCRVJyA0tJUBIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $604 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:603.90&airProductToken=AQqYAQo0CNWCARIEMzQ4ORiBLSDEjQEo-JyKAzDRnYoDOFRAAFgBagdFQ09OT01ZcghUTkE3QTlETgo1CNWCARIEMTU1NhjEjQEgsqIBKNqeigMwyaCKAzhUQAFYAWoHRUNPTk9NWXIIVE5BN0E5RE4KKQi5lgESAjQxGLKiASCMyAEowaKKAzDzoooDOFNAAVgBagJFUnIDU0lQEgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, Apr 13 - Fri, Apr 17 BUF Buffalo MAZ Mayagüez $614 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:BUF,to:MAZ,departure:4/13/2026TANYT&leg2=from:MAZ,to:BUF,departure:4/17/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:613.90&airProductToken=AQqYAQo0CNWCARIEMzQ4ORiBLSDEjQEo-JyKAzDRnYoDOFRAAFgBagdFQ09OT01ZcghUTkE3QTlETgo1CNWCARIEMTU1NhjEjQEgsqIBKNqeigMwyaCKAzhUQAFYAWoHRUNPTk9NWXIIVE5BN0E5RE4KKQi5lgESAjQwGLKiASCMyAEoqaGKAzDboYoDOEtAAVgBagJFUnIDS0lQEgoIARABGAEqAlVBGAEiBAgBEAEoAigDKAQwAQ) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=FTG_SPRING_PROMO_) ## Alternative airports near Mayagüez Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.com/Flights-Search?leg1=from:BUF,to:BQN,departure:3/29/2026TANYT&leg2=from:BQN,to:BUF,departure:4/2/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) BQN Rafael Hernandez Cheapest 33 min [Flights from $426 ](https://www.expedia.com/Flights-Search?leg1=from:BUF,to:BQN,departure:3/29/2026TANYT&leg2=from:BQN,to:BUF,departure:4/2/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) ## Frequently asked questions ### How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos) cost? ### What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ### How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos) flight with Expedia? ### Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos) at the last minute? ### Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos) flight and hotel package? ### Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Mayagüez (MAZ-Eugenio María de Hostos)? ## Travel information | Origin airport | Buffalo Niagara Intl. | | ------------------- | ----------------------- | | Destination airport | Eugenio María de Hostos | | Roundtrip price | $522 | | Distance | 1834 mi | ## Book with confidence # Buffalo to Mayagüez Flights The cheapest times to fly from Buffalo to Mayagüez On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Mayagüez are during the month of April. You can find some of the cheapest flights from Buffalo to Mayagüez with Expedia's search tool and vast selection of airlines. The best time to book a flight from Buffalo to Mayagüez Sunday is one of the best days to book for cheap flights from Buffalo to Mayagüez: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. How to find cheap round-trip tickets from Buffalo to Mayagüez Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Mayagüez in 2026\. You can also book with separate airlines for your outbound and return journeys, from $254 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Mayagüez flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Buffalo to Mayagüez airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. \*Terms apply. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. 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