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$266 Cheap Flights from Des Moines (DSM) to Greensboro (GSO)

View $266 flight on Sat, Oct 24, 2026Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Piedmont Triad Intl. Airport (GSO)

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Cheap Flights from Des Moines to Greensboro (DSM-GSO)

Prices were available within the past 7 days and start at $266 for one-way flights and $334 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 30 - Sat, Oct 31
DSM
Des Moines
GSO
Greensboro
$334 Roundtrip, found 1 day ago
$334
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 30 from Des Moines to Greensboro, returning Sat, Oct 31, priced at $334 found 1 day ago
Delta
Sat, Oct 24 - Mon, Oct 26
DSM
Des Moines
GSO
Greensboro
$339 Roundtrip, just found
$339
Roundtrip
just found
Select Delta flight, departing Sat, Oct 24 from Des Moines to Greensboro, returning Mon, Oct 26, priced at $339 just found
United
Tue, Jan 26 - Sun, Jan 31
DSM
Des Moines
GSO
Greensboro
$339 Roundtrip, just found
$339
Roundtrip
just found
Select United flight, departing Tue, Jan 26 from Des Moines to Greensboro, returning Sun, Jan 31, priced at $339 just found
American Airlines
Tue, Jan 26 - Sun, Jan 31
DSM
Des Moines
GSO
Greensboro
$340 Roundtrip, just found
$340
Roundtrip
just found
Select American Airlines flight, departing Tue, Jan 26 from Des Moines to Greensboro, returning Sun, Jan 31, priced at $340 just found
United
Tue, Jan 26 - Sun, Jan 31
DSM
Des Moines
GSO
Greensboro
$344 Roundtrip, just found
$344
Roundtrip
just found
Select United flight, departing Tue, Jan 26 from Des Moines to Greensboro, returning Sun, Jan 31, priced at $344 just found
United
Mon, Jan 25 - Sat, Jan 30
DSM
Des Moines
GSO
Greensboro
$349 Roundtrip, found 6 hours ago
$349
Roundtrip
found 6 hours ago
Select United flight, departing Mon, Jan 25 from Des Moines to Greensboro, returning Sat, Jan 30, priced at $349 found 6 hours ago
United
Wed, Sep 30 - Sat, Oct 31
DSM
Des Moines
GSO
Greensboro
$350 Roundtrip, found 1 day ago
$350
Roundtrip
found 1 day ago
Select United flight, departing Wed, Sep 30 from Des Moines to Greensboro, returning Sat, Oct 31, priced at $350 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
DSM
Des Moines
GSO
Greensboro
$353 Roundtrip, found 1 day ago
$353
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Des Moines to Greensboro, returning Sat, Oct 24, priced at $353 found 1 day ago
United
Wed, Sep 30 - Sat, Oct 31
DSM
Des Moines
GSO
Greensboro
$355 Roundtrip, found 1 day ago
$355
Roundtrip
found 1 day ago
Select United flight, departing Wed, Sep 30 from Des Moines to Greensboro, returning Sat, Oct 31, priced at $355 found 1 day ago
United
Tue, Oct 20 - Sat, Oct 24
DSM
Des Moines
GSO
Greensboro
$359 Roundtrip, found 1 day ago
$359
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 20 from Des Moines to Greensboro, returning Sat, Oct 24, priced at $359 found 1 day ago

What you need to know for your flight from Des Moines Intl. to Piedmont Triad Intl.

Des Moines (DSM) to Greensboro (GSO) at a glance

Discover a range of airlines offering flights from Des Moines (DSM) to Greensboro (GSO) on this domestic short-haul route. Compare various options from full-service carriers to find the itinerary that aligns with your budget, schedule, and travel plans as you set out to explore Greensboro's renowned attractions and neighborhoods. Get all the essential information for your journey from Des Moines International Airport (DSM) to Piedmont Triad International Airport (GSO).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$410, depending on seasonality and how far ahead you book

Flights from Des Moines International Airport (DSM) to Piedmont Triad International Airport (GSO)

According to recent traveler bookings, the top airline choices from Des Moines to Greensboro typically feature one-stop services, with popular layover options at O'Hare International Airport (ORD, approximately 1 hour 30 minutes), Hartsfield-Jackson Atlanta International Airport (ATL, around 1 hour), and Charlotte-Douglas International Airport (CLT, about 1 hour 30 minutes). These routes provide you with the flexibility to adjust your itinerary based on price, total travel time, and cabin class to secure the best travel experience.

  • Delta: This full-service airline provides one-stop flights, capturing around 42% of departures on this route. One-way ticket prices generally range from $125 to $375, with an in-flight duration of 3 hours and 30 minutes and a total travel time of about 5 hours, including layover.
  • American Airlines: Another full-service option, American Airlines operates one-stop services and constitutes roughly 40% of departures. One-way fares typically fall between $125 and $420, with a flight time of 3 hours and 30 minutes, leading to a complete journey time of approximately 5 hours, factoring in the layover.
  • United: Offering one-stop service as a full-service carrier, United accounts for about 18% of departures on this route. One-way prices usually range from $135 to $455, with an in-flight time of 3 hours and 30 minutes, resulting in a total journey time of close to 5 hours, including layover.

Travelers flying from Des Moines to Greensboro can opt for an upgraded experience, as Delta provides premium economy class service on this route.

Best time to fly from Des Moines (DSM) to Greensboro (GSO)

The most popular months for travelers flying from Des Moines to Greensboro are April, June, and October, when peak temperatures in Greensboro reach up to 75.2°F in June. If you prefer quieter travel, consider August, the least busy time to visit with temperatures around 76.8°F and typically the lowest average one-way fare (around $137). Flight availability peaks in October, with approximately 12 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $137, roughly 35% cheaper than the yearly average.
  • Most flight options: October has the highest number of flights from Des Moines to Greensboro, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January38.8°F (3.8°C)Average8$238
February42.8°F (6.0°C)Average7$183
March49.5°F (9.7°C)Average8$219
April58.8°F (14.9°C)High9$271
May67.5°F (19.7°C)Average8$194
June75.2°F (24.0°C)High9$188
July79.0°F (26.1°C)Average9$172
August76.8°F (24.9°C)Low7$137
September71.2°F (21.8°C)Average9$197
October60.8°F (16.0°C)High12$260
November49.3°F (9.6°C)Low9$273
December43.5°F (6.4°C)Low8$194

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Des Moines (DSM) to Greensboro (GSO)

  • Des Moines to Winston-Salem (DSM-INT): Located approximately 16 miles from Piedmont Triad International Airport (GSO), Smith Reynolds Airport (INT) serves as a key alternative for travelers.
  • Fort Dodge to Greensboro (FOD-GSO): Fort Dodge Regional Airport (FOD) is positioned around 76 miles from Des Moines International Airport (DSM), providing another option for flight connections.

How to find the best prices for flights from Des Moines (DSM) to Greensboro (GSO)

Getting some of the best deals on flights from Des Moines to Greensboro is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures, between 5 a.m. and 12 p.m., tend to be the most affordable and popular. Additionally, flying on Thursday often results in lower prices and is recognized as the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Piedmont Triad International Airport from Des Moines International Airport

Greensboro welcomes travelers from Des Moines with a range of transport options based on price, convenience, and proximity. Here's how to reach Greensboro efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greensboro, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Piedmont Triad International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Piedmont Triad International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) cost?
You can find cheap one-way flights from $266 and cheap return flights from $334 Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) with Expedia. One-way flights generally range between $193 and $691, and roundtrip flights usually range from $323 to $1085. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
The cheapest month to fly from DSM to GSO is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
Enter DSM to GSO and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
Delta is one of the cheapest airlines offering connecting flights from Des Moines (DSM) to Greensboro (GSO), starting from around $265 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
To find a cheap flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
The earliest flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) typically departs at around 5:00 AM, operated by American Airlines. This is a seasonal service active in March, and an early departure allows you to make the most of your time in Greensboro. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
The most popular departure times for flights from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) are in the early morning, from 6am to 9am. About 25% of passengers prefer this time window. Many major carriers, including American Airlines, Delta, and United Airlines, offer flights during this window. This timing is popular because it allows you to make the most of your day upon arrival.
How long does it take to fly from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
Flights from DSM to GSO with one stop typically take around 4 hours 30 minutes, covering approximately 827 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
First class seats are offered on the DSM to GSO route. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) flight with Expedia?
It's easy to earn miles on a Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greensboro from Des Moines Intl. (DSM)?
If you're planning to travel to Greensboro from Des Moines Intl. (DSM), you can fly into Piedmont Triad Intl. (GSO) Some flights may connect through major hubs like O'Hare Intl. (ORD), Denver Intl. (DEN), Minneapolis - St. Paul Intl. (MSP) before reaching Greensboro. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) at the last minute?
Typically, booking a last minute flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) flight and hotel package?
Securing a Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) Greensboro Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.)?
If you booked your Des Moines, IA (DSM-Des Moines Intl.) to Greensboro, NC (GSO-Piedmont Triad Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Piedmont Triad Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$333
Distance
826 mi

Book with confidence

Des Moines to Greensboro Flights

The cheapest times to fly from Des Moines to Greensboro

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Greensboro are during the month of September. You can find some of the cheapest flights from Des Moines to Greensboro with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Greensboro

Sunday is one of the best days to book for cheap flights from Des Moines to Greensboro: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Greensboro

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Greensboro in 2026. You can also book with separate airlines for your outbound and return journeys, from $266 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Greensboro flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Greensboro airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Greensboro Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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