Cheap Flights from Des Moines (DSM) to Isla Mujeres (ISJ)

Popular airlines from Des Moines International Airport (DSM) to Isla Mujeres, Quintana Roo (ISJ)

Alternative airports near Isla Mujeres

Prices were available within the past 7 days. Prices and availability are subject to change.

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Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ) cost?
Secure a cheap one-way flight or cheap return flight from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ)?
The cheapest month to fly from DSM to ISJ is , when there's less demand. Off-peak season is often when airlines offer better prices between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ)?
To find the cheapest airline that'll fly you from DSM to ISJ, use Expedia's filter tool. Tailor your search based on your travel style, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to see the cheapest fares upfront.
How many flights per day from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ)?
Nonstop flights from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filters. Enter your travel dates and choose either "1 Stop" or "2+ Stops."
What day of the week has the most flights from DSM to ISJ?
You'll generally find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ)?
Opt for a flight from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ) that leaves before 3 PM to reduce the likelihood of delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ) last-minute?
Booking your plane ticket from DSM to ISJ right before your journey is typically more expensive. But if there's some wiggle room with your itinerary, you could grab a cheap last-minute fare.
Is it cheaper to book a DSM to ISJ flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to ISJ flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place takes the hassle out of planning your trip. Simply secure your flights and choose from our wide range of stays, then tailor your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Isla Mujeres Airport (ISJ)?
You can usually cancel or reschedule your DSM to ISJ flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Isla Mujeres
Distance
1458 mi

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Des Moines to Isla Mujeres Flights

The cheapest times to fly from Des Moines to Isla Mujeres

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Isla Mujeres are during the month of . You can find some of the cheapest flights from Des Moines to Isla Mujeres with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Isla Mujeres

Sunday is one of the best days to book for cheap flights from Des Moines to Isla Mujeres: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Isla Mujeres

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Isla Mujeres in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Isla Mujeres flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Isla Mujeres airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Isla Mujeres Flights

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*Available to One Key members.