$239 Cheap Flights from Des Moines (DSM) to Mobile (MOB)

View $239 flight on Thu, Nov 13, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Mobile Regional Airport (MOB)

Cheap Flights from Des Moines to Mobile (DSM-MOB)

Prices were available within the past 7 days and start at $239 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sat, Nov 15 - Tue, Nov 18
DSM
Des Moines
MOB
Mobile
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select Delta flight, departing Sat, Nov 15 from Des Moines to Mobile, returning Tue, Nov 18, priced at $249 found 2 hours ago
Delta
Tue, Nov 4 - Tue, Nov 18
DSM
Des Moines
MOB
Mobile
$254 Roundtrip, found 4 days ago
$254
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Nov 4 from Des Moines to Mobile, returning Tue, Nov 18, priced at $254 found 4 days ago
Delta
Wed, Nov 12 - Tue, Nov 18
DSM
Des Moines
MOB
Mobile
$254 Roundtrip, found 2 hours ago
$254
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Nov 12 from Des Moines to Mobile, returning Tue, Nov 18, priced at $254 found 2 hours ago
Delta
Fri, Oct 24 - Sat, Nov 8
DSM
Des Moines
MOB
Mobile
$279 Roundtrip, found 4 days ago
$279
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Oct 24 from Des Moines to Mobile, returning Sat, Nov 8, priced at $279 found 4 days ago
Delta
Sat, Nov 8 - Tue, Nov 18
DSM
Des Moines
MOB
Mobile
$284 Roundtrip, found 14 hours ago
$284
Roundtrip
found 14 hours ago
Select Delta flight, departing Sat, Nov 8 from Des Moines to Mobile, returning Tue, Nov 18, priced at $284 found 14 hours ago
Delta
Fri, Oct 24 - Tue, Nov 11
DSM
Des Moines
MOB
Mobile
$284 Roundtrip, found 4 days ago
$284
Roundtrip
found 4 days ago
Select Delta flight, departing Fri, Oct 24 from Des Moines to Mobile, returning Tue, Nov 11, priced at $284 found 4 days ago
Delta
Mon, Nov 3 - Sat, Nov 8
DSM
Des Moines
MOB
Mobile
$289 Roundtrip, found 1 day ago
$289
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 3 from Des Moines to Mobile, returning Sat, Nov 8, priced at $289 found 1 day ago
Delta
Wed, Nov 12 - Sat, Nov 15
DSM
Des Moines
MOB
Mobile
$289 Roundtrip, found 2 hours ago
$289
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Nov 12 from Des Moines to Mobile, returning Sat, Nov 15, priced at $289 found 2 hours ago
United
Fri, Oct 31 - Sun, Nov 2
DSM
Des Moines
MOB
Mobile
$295 Roundtrip, found 1 day ago
$295
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 31 from Des Moines to Mobile, returning Sun, Nov 2, priced at $295 found 1 day ago
American Airlines
Tue, Nov 11 - Thu, Nov 20
DSM
Des Moines
MOB
Mobile
$319 Roundtrip, found 2 hours ago
$319
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Nov 11 from Des Moines to Mobile, returning Thu, Nov 20, priced at $319 found 2 hours ago

Find the cheapest month to fly from Des Moines (DSM) to Mobile (MOB)

February is typically the cheapest month to fly

From $224 - $560 per traveler.

Alternative airports near Mobile

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Mobile Regional MOB. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $254
MOB
Mobile Regional
Cheapest
Average driving time to city center22 min
Flights from $254

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB) cost?
Get a cheap one-way flight from $239 or cheap return flight from $249 from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB)?
The cheapest month to fly from DSM to MOB is November, when there's less demand. Off-peak months are usually when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from DSM to MOB. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB)?
You'll have to take a flight with a layover when traveling from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB). Direct flights don't operate daily on this route. However, simply filter your search to include one or two stops to find an option that works for you.
What day of the week has the most flights from DSM to MOB?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can change from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB)?
To arrive at Mobile Regional Airport (MOB) on time, pick a flight that takes off from Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB) last-minute?
Waiting until right before your break to book a flight from DSM to MOB often results in higher prices. Although you may find some last-minute deals, they're not always guaranteed. Be flexible with your travel plans to boost your chances of scoring a bargain.
Is it cheaper to book a DSM to MOB flight and hotel package?
Compared with arranging hotels and flights separately, booking a DSM to MOB flight and hotel package with Expedia could lead to significant savings. Better yet, managing everything in one place will take the hassle out of planning your trip. Simply secure your flights and select from our extensive range of stays, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Mobile Regional Airport (MOB)?
Typically, it's possible to cancel or reschedule your DSM to MOB flight. However, if the booking was made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

Travel information

Origin airport
Des Moines Intl.
Destination airport
Mobile Regional
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
807 mi

Book with confidence

Des Moines to Mobile Flights

The cheapest times to fly from Des Moines to Mobile

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Mobile are during the month of November. You can find some of the cheapest flights from Des Moines to Mobile with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Mobile

Sunday is one of the best days to book for cheap flights from Des Moines to Mobile: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Mobile

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Mobile in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Mobile flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Mobile airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Des Moines to Mobile Flights

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*Available to One Key members.