$380 Cheap Flights from Des Moines (DSM) to Santa Rosa (STS)

View $380 flight on Fri, Sep 12, 2025Opens in a new window

Popular airlines from Des Moines International Airport (DSM) to Santa Rosa, CA (STS-Sonoma County)

Cheap Flights from Des Moines to Santa Rosa (DSM-STS)

Prices were available within the past 7 days and start at $380 for one-way flights and $669 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Apr 22 - Sat, Apr 25
DSM
Des Moines
STS
Santa Rosa
$669 Roundtrip, found 4 days ago
$669
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 22 from Des Moines to Santa Rosa, returning Sat, Apr 25, priced at $669 found 4 days ago
American Airlines
Tue, Sep 9 - Tue, Sep 16
DSM
Des Moines
STS
Santa Rosa
$695 Roundtrip, found 2 days ago
$695
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 9 from Des Moines to Santa Rosa, returning Tue, Sep 16, priced at $695 found 2 days ago
American Airlines
Thu, Sep 18 - Mon, Sep 22
DSM
Des Moines
STS
Santa Rosa
$699 Roundtrip, found 1 day ago
$699
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Sep 18 from Des Moines to Santa Rosa, returning Mon, Sep 22, priced at $699 found 1 day ago
American Airlines
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines
STS
Santa Rosa
$719 Roundtrip, found 4 days ago
$719
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Apr 23 from Des Moines to Santa Rosa, returning Sun, Apr 26, priced at $719 found 4 days ago
American Airlines
Fri, Sep 12 - Mon, Sep 15
DSM
Des Moines
STS
Santa Rosa
$724 Roundtrip, found 2 days ago
$724
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Des Moines to Santa Rosa, returning Mon, Sep 15, priced at $724 found 2 days ago
American Airlines
Wed, Sep 10 - Tue, Sep 16
DSM
Des Moines
STS
Santa Rosa
$729 Roundtrip, found 2 days ago
$729
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, Sep 10 from Des Moines to Santa Rosa, returning Tue, Sep 16, priced at $729 found 2 days ago
American Airlines
Sat, Oct 11 - Wed, Oct 15
DSM
Des Moines
STS
Santa Rosa
$735 Roundtrip, found 4 days ago
$735
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 11 from Des Moines to Santa Rosa, returning Wed, Oct 15, priced at $735 found 4 days ago
American Airlines
Tue, Sep 9 - Mon, Sep 15
DSM
Des Moines
STS
Santa Rosa
$740 Roundtrip, found 2 days ago
$740
Roundtrip
found 2 days ago
Select American Airlines flight, departing Tue, Sep 9 from Des Moines to Santa Rosa, returning Mon, Sep 15, priced at $740 found 2 days ago
American Airlines
Fri, Sep 12 - Mon, Sep 15
DSM
Des Moines
STS
Santa Rosa
$744 Roundtrip, found 2 days ago
$744
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Sep 12 from Des Moines to Santa Rosa, returning Mon, Sep 15, priced at $744 found 2 days ago
Alaska Airlines
Wed, Oct 15 - Sat, Oct 18
DSM
Des Moines
STS
Santa Rosa
$769 Roundtrip, found 4 days ago
$769
Roundtrip
found 4 days ago
Select Alaska Airlines flight, departing Wed, Oct 15 from Des Moines to Santa Rosa, returning Sat, Oct 18, priced at $769 found 4 days ago

Alternative airports near Santa Rosa

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Sonoma County STS. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $804
STS
Sonoma County
CheapestClosest
Average driving time to city center10 min
Flights from $804
Flights from Des Moines (DSM) to Santa Rosa (STS)
Origin airport
Des Moines Intl.
Destination airport
Sonoma County
Airlines serving
Alaska Airlines, American Airlines
Roundtrip price
$668
Distance
1549 mi

Des Moines to Santa Rosa Flights

The cheapest times to fly from Des Moines to Santa Rosa

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Des Moines to Santa Rosa are during the month of April. You can find some of the cheapest flights from Des Moines to Santa Rosa with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Des Moines to Santa Rosa

Sunday is one of the best days to book for cheap flights from Des Moines to Santa Rosa: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Des Moines to Santa Rosa

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Des Moines to Santa Rosa in 2025. You can also book with separate airlines for your outbound and return journeys, from $380 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Des Moines to Santa Rosa flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Des Moines to Santa Rosa airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS) cost?
Get a cheap one-way flight from $380 or cheap return flight from $669 from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS)?
April is the most affordable month to fly from DSM to STS. Planning your trip for the off-season is often the key to scoring lower fares.
What is the cheapest airline that flies from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest DSM to STS flight.
How many flights per day from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS)?
There aren't any daily nonstop flights departing from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS). But you can book flights with layovers. Filter your search results on Expedia to include one or two stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from DSM to STS?
You'll typically find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS)?
To touch down at Sonoma County Airport (STS) on schedule, opt for a flight that takes off from Des Moines Intl. Airport (DSM) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS) last-minute?
Booking your flight from DSM to STS right before your journey is typically more expensive. But if there's some wiggle room with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book a DSM to STS flight and hotel package?
Compared with arranging flights and hotels separately, booking a DSM to STS flight and hotel package with Expedia could lead to significant savings. Better still, having everything in one place takes the hassle out of travel planning. Just secure your flights and select from our wide range of hotels, then personalize your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from Des Moines Intl. Airport (DSM) to Sonoma County Airport (STS)?
It's usually possible to reschedule or cancel your DSM to STS flight. However, for bookings made more than 24 hours ago, additional charges may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.