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$163 Cheap Flights from Manchester (MHT) to Greenville (GSP)

View $163 flight on Wed, Oct 7, 2026Opens in a new window

Popular airlines from Manchester-Boston Regional Airport (MHT) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Manchester to Greenville (MHT-GSP)

Prices were available within the past 7 days and start at $163 for one-way flights and $325 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, Oct 3 - Mon, Oct 5
MHT
Manchester
GSP
Greenville
$325 Roundtrip, found 12 hours ago
$325
Roundtrip
found 12 hours ago
Select United flight, departing Sat, Oct 3 from Manchester to Greenville, returning Mon, Oct 5, priced at $325 found 12 hours ago
American Airlines
Wed, Oct 7 - Wed, Oct 14
MHT
Manchester
GSP
Greenville
$325 Roundtrip, found 1 day ago
$325
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Oct 7 from Manchester to Greenville, returning Wed, Oct 14, priced at $325 found 1 day ago
Southwest Airlines
Fri, Oct 30 - Wed, Nov 4
MHT
Manchester
GSP
Greenville
$353 Roundtrip, found 12 hours ago
$353
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from Manchester to Greenville, returning Wed, Nov 4, priced at $353 found 12 hours ago
American Airlines
Fri, Oct 16 - Mon, Oct 19
MHT
Manchester
GSP
Greenville
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 16 from Manchester to Greenville, returning Mon, Oct 19, priced at $358 found 1 day ago
Southwest Airlines
Fri, Nov 13 - Tue, Nov 17
MHT
Manchester
GSP
Greenville
$364 Roundtrip, found 2 days ago
$364
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Fri, Nov 13 from Manchester to Greenville, returning Tue, Nov 17, priced at $364 found 2 days ago
Southwest Airlines
Fri, Oct 30 - Wed, Nov 4
MHT
Manchester
GSP
Greenville
$365 Roundtrip, found 12 hours ago
$365
Roundtrip
found 12 hours ago
Select Southwest Airlines flight, departing Fri, Oct 30 from Manchester to Greenville, returning Wed, Nov 4, priced at $365 found 12 hours ago
American Airlines
Fri, Oct 16 - Mon, Oct 19
MHT
Manchester
GSP
Greenville
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 16 from Manchester to Greenville, returning Mon, Oct 19, priced at $367 found 1 day ago
American Airlines
Thu, Nov 12 - Mon, Nov 16
MHT
Manchester
GSP
Greenville
$373 Roundtrip, found 3 days ago
$373
Roundtrip
found 3 days ago
Select American Airlines flight, departing Thu, Nov 12 from Manchester to Greenville, returning Mon, Nov 16, priced at $373 found 3 days ago
American Airlines
Fri, Nov 13 - Tue, Nov 17
MHT
Manchester
GSP
Greenville
$377 Roundtrip, found 2 days ago
$377
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Nov 13 from Manchester to Greenville, returning Tue, Nov 17, priced at $377 found 2 days ago
American Airlines
Fri, Nov 13 - Tue, Nov 17
MHT
Manchester
GSP
Greenville
$378 Roundtrip, found 2 days ago
$378
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Nov 13 from Manchester to Greenville, returning Tue, Nov 17, priced at $378 found 2 days ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $497
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $497

What you need to know for your flight from Manchester-Boston Regional to Greenville-Spartanburg Intl.

Manchester (MHT) to Greenville (GSP) at a glance

Travel to Greenville (GSP) from Manchester (MHT) with a selection of airlines on this domestic short-haul route. Discover cheap flights from Manchester and compare weekly flights to find the best airfares to Greenville that suit your budget and schedule. Whether you prefer full-service or low-cost options, you’ll find an itinerary that aligns with your travel plans as you explore the iconic sights and neighborhoods of Greenville.

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1 hour layover with one stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$400, depending on seasonality and how far ahead you book

Flights from Manchester-Boston Regional Airport (MHT) to Greenville-Spartanburg International Airport (GSP)

Based on the latest traveler bookings, here are the top airlines preferred for flights from Manchester to Greenville, primarily featuring one-stop services. Popular layover points include Philadelphia International Airport (PHL) with approximately a 1-hour stop, Baltimore Washington International Thurgood Marshall Airport (BWI) also around 1 hour, and Ronald Reagan Washington National Airport (DCA), which offers a similar layover duration. This allows you to mix and match options based on price, total travel time, and cabin class to create your ideal itinerary.

  • American Airlines: This full-service airline provides one-stop flights, representing around 62% of departures for this route. One-way ticket prices generally range from $120 to $395. You can expect an in-flight duration of 3 hours and 30 minutes, with an overall travel time of approximately 4 hours and 30 minutes, including layover.
  • Southwest Airlines: Known as a budget-friendly option, this low-cost carrier handles about 27% of the departures along this route. One-way fares typically fall between $120 and $400. The in-flight time is 3 hours and 30 minutes, while the total journey time, including layover, is around 4 hours and 30 minutes.
  • United: Another full-service airline, United offers one-stop flights and constitutes about 11% of the departures on this route. One-way fares are usually between $125 and $405. Expect 3 hours and 30 minutes of flying time, with a total travel duration of roughly 4 hours and 30 minutes, including the layover.

Best time to fly from Manchester (MHT) to Greenville (GSP)

The most popular months for travelers flying from Manchester to Greenville are March, April, and August, when peak temperatures in Greenville reach up to 77.5°F in August. If you prefer quieter travel, consider November, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 51.1°F. For better deals, August usually offers the lowest average one-way fare around $177. Flight availability peaks in June and August, with approximately 11 flights per week, making it easier to find convenient departure times. February has the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $177, roughly 23% cheaper than the yearly average.
  • Another budget-friendly time to fly: January typically offers an average one-way fare of around $196.
  • Most flight options: June and August have the highest number of flights from Manchester to Greenville, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January41.4°F (5.2°C)Average8$196
February45.3°F (7.4°C)Average7$241
March51.8°F (11.0°C)High9$219
April59.9°F (15.5°C)High9$209
May68.4°F (20.2°C)Average8$258
June76.1°F (24.5°C)Average11$224
July79.5°F (26.4°C)Low8$241
August77.5°F (25.3°C)High11$177
September72.3°F (22.4°C)Average8$200
October61.9°F (16.6°C)Low8$304
November51.1°F (10.6°C)Low8$237
December45.3°F (7.4°C)Average8$250

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative routes from Manchester (MHT) to Greenville (GSP)

  • Manchester to Greenville (MHT-GMU): Located approximately 8 miles from Greenville-Spartanburg International Airport (GSP), Greenville Downtown Airport (GMU) serves the region.
  • Nashua to Greenville (ASH-GSP): Nashua Municipal Airport (ASH) is roughly 11 miles away from Manchester-Boston Regional Airport (MHT), connecting travelers to the area.
  • Portsmouth to Greenville (PSM-GSP): Portsmouth International Airport (PSM) lies about 33 miles from Manchester-Boston Regional Airport (MHT), providing access for flights.

How to find the best prices for flights from Manchester (MHT) to Greenville (GSP)

Getting some of the best deals on flights from Manchester to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are typically available when booking at least two months in advance, although most travelers reserve their flights 2-8 weeks ahead. Departures in the morning (5 a.m. to 12 p.m.) usually offer lower prices and are quite popular, while flying on Tuesday often results in cheaper tickets, even though Wednesday is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Manchester-Boston Regional Airport

Greenville welcomes travelers from Manchester with a range of transport options based on price, convenience, and proximity. For departures, Manchester-Boston Regional Airport is roughly a 15-minute drive (covering about 7 miles) from central Manchester. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Frequently asked questions

How much does a flight from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?
You can find cheap one-way flights from $163 and cheap return flights from $325 Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $152 and $539, and return flights often range between $363 and $970. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
September is the cheapest month to fly from Manchester, NH (MHT) to Greenville, SC (GSP), with average round-trip fares around $334. This price is about 16% lower than the average for the year, likely due to reduced travel demand after the summer. Other affordable months to consider for this route are March and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Enter MHT to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting flights from Manchester, NH (MHT) to Greenville, SC (GSP), with round-trip tickets starting from around $236. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
To find a cheap flight from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
When flying from Manchester, NH (MHT) to Greenville, SC (GSP), consider traveling in August or September. These months typically feature return flights priced around $334, making them budget-friendly options. They are also popular travel months, giving you a good selection of flights to choose from.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
The earliest flight from Manchester, NH (MHT) to Greenville, SC (GSP) typically departs at around 5:00 AM, operated by Southwest Airlines. This seasonal service is active in December, allowing you to start your journey early and make the most of your time in Greenville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
For flights from Manchester, NH (MHT) to Greenville, SC (GSP), the most popular departure times are in the late afternoon, from 3pm to 6pm. About 27% of passengers choose this time window. Many major carriers, including American Airlines and Southwest Airlines, operate flights during this period. This timing is favored as it allows travelers to have a full day before heading to the airport.
How long does it take to fly from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
A flight from MHT to GSP with a layover takes around 4 hours 30 minutes, with the route covering approximately 801 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
First class seats are offered on the MHT to GSP route with American Airlines and United Airlines.
How do I earn miles on a Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?
It's easy to earn miles on a Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Greenville from Manchester-Boston Regional (MHT)?
When traveling from Manchester-Boston Regional (MHT) to Greenville, you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP). Some flights may connect through major hubs like Ronald Reagan Washington National (DCA), Philadelphia Intl. (PHL) before reaching Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?
Typically, booking a last minute flight from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?
Securing a Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?
If you booked your Manchester, NH (MHT-Manchester-Boston Regional) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Manchester-Boston Regional
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Southwest Airlines, United
Roundtrip price
$324
Distance
801 mi

Book with confidence

Manchester to Greenville Flights

The cheapest times to fly from Manchester to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Manchester to Greenville are during the month of October. You can find some of the cheapest flights from Manchester to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Manchester to Greenville

Sunday is one of the best days to book for cheap flights from Manchester to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Manchester to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Manchester to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $163 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Manchester to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Manchester to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Manchester to Greenville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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