$199 Cheap Flights from Moline (MLI) to Greenville (GSP)

View $199 flight on Tue, Oct 28, 2025Opens in a new window

Popular airlines from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)

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Cheap Flights from Moline to Greenville (MLI-GSP)

Prices were available within the past 7 days and start at $199 for one-way flights and $249 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, Oct 3 - Wed, Oct 8
MLI
Moline
GSP
Greenville
$249 Roundtrip, found 3 hours ago
$249
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Oct 3 from Moline to Greenville, returning Wed, Oct 8, priced at $249 found 3 hours ago
Delta
Tue, Sep 2 - Tue, Sep 16
MLI
Moline
GSP
Greenville
$254 Roundtrip, found 1 day ago
$254
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 2 from Moline to Greenville, returning Tue, Sep 16, priced at $254 found 1 day ago
American Airlines
Thu, Oct 2 - Wed, Oct 8
MLI
Moline
GSP
Greenville
$254 Roundtrip, found 2 hours ago
$254
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Oct 2 from Moline to Greenville, returning Wed, Oct 8, priced at $254 found 2 hours ago
United
Tue, Oct 28 - Sat, Nov 1
MLI
Moline
GSP
Greenville
$267 Roundtrip, found 1 day ago
$267
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 28 from Moline to Greenville, returning Sat, Nov 1, priced at $267 found 1 day ago
Delta
Mon, Sep 29 - Sat, Oct 4
MLI
Moline
GSP
Greenville
$279 Roundtrip, found 1 day ago
$279
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Sep 29 from Moline to Greenville, returning Sat, Oct 4, priced at $279 found 1 day ago
American Airlines
Fri, Oct 3 - Wed, Oct 8
MLI
Moline
GSP
Greenville
$293 Roundtrip, found 3 hours ago
$293
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Fri, Oct 3 from Moline to Greenville, returning Wed, Oct 8, priced at $293 found 3 hours ago
American Airlines
Thu, Oct 2 - Wed, Oct 8
MLI
Moline
GSP
Greenville
$294 Roundtrip, found 2 hours ago
$294
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Oct 2 from Moline to Greenville, returning Wed, Oct 8, priced at $294 found 2 hours ago
American Airlines
Thu, Oct 2 - Wed, Oct 8
MLI
Moline
GSP
Greenville
$298 Roundtrip, found 2 hours ago
$298
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Thu, Oct 2 from Moline to Greenville, returning Wed, Oct 8, priced at $298 found 2 hours ago
American Airlines
Thu, Oct 2 - Sun, Oct 5
MLI
Moline
GSP
Greenville
$299 Roundtrip, found 1 day ago
$299
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Oct 2 from Moline to Greenville, returning Sun, Oct 5, priced at $299 found 1 day ago
United
Tue, Oct 28 - Sat, Nov 1
MLI
Moline
GSP
Greenville
$300 Roundtrip, found 1 day ago
$300
Roundtrip
found 1 day ago
Select United flight, departing Tue, Oct 28 from Moline to Greenville, returning Sat, Nov 1, priced at $300 found 1 day ago

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Greenville-Spartanburg Intl. GSP. Cheapest option available. Average driving time to city center is 18 minutes. Flights from $462
GSP
Greenville-Spartanburg Intl.
Cheapest
Average driving time to city center18 min
Flights from $462
Flights from Moline (MLI) to Greenville (GSP)
Origin airport
Quad City Intl.
Destination airport
Greenville-Spartanburg Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$248
Distance
638 mi

Moline to Greenville Flights

The cheapest times to fly from Moline to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Moline to Greenville are during the month of October. You can find some of the cheapest flights from Moline to Greenville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Moline to Greenville

Sunday is one of the best days to book for cheap flights from Moline to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Moline to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Moline to Greenville in 2025. You can also book with separate airlines for your outbound and return journeys, from $199 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Moline to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Moline to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP) cost?
Lock in a cheap one-way flight from $199 or cheap return flight from $249 from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)?
October is the cheapest month to fly from MLI to GSP. Traveling during quieter months is often the key to finding a great deal.
What is the cheapest airline that flies from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from MLI to GSP. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)?
There are no daily nonstop flights available from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP). But you can opt for flights with layovers. Filter your search results on Expedia to include one or more stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from MLI to GSP?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change depending on a number of factors, including the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)?
To avoid potential delays on the Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP) route, travel before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP) last-minute?
Booking your plane ticket from MLI to GSP right before your trip is typically more expensive. However, if you're flexible with your departure dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a MLI to GSP flight and hotel package?
Opting for a MLI to GSP flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your trip all in one place. Select from our wide range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Quad City Intl. Airport (MLI) to Greenville-Spartanburg Intl. Airport (GSP)?
You can usually cancel or reschedule your MLI to GSP flight. However, if it's been more than 24 hours since booking, additional fees may apply. Check your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more details on our Customer Service portal.

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*Available to One Key members.