$245 Cheap Flights from Mobile (MOB) to Columbia (COU)

View $245 flight on Tue, May 12, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Columbia, MO (COU-Columbia Regional)

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Cheap Flights from Mobile to Columbia (MOB-COU)

Prices were available within the past 7 days and start at $245 for one-way flights and $339 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Wed, Apr 15 - Tue, Apr 21
MOB
Mobile
COU
Columbia
$339 Roundtrip, found 3 days ago
$339
Roundtrip
found 3 days ago
Select United flight, departing Wed, Apr 15 from Mobile to Columbia, returning Tue, Apr 21, priced at $339 found 3 days ago
United
Wed, Apr 15 - Wed, Apr 22
MOB
Mobile
COU
Columbia
$369 Roundtrip, found 3 days ago
$369
Roundtrip
found 3 days ago
Select United flight, departing Wed, Apr 15 from Mobile to Columbia, returning Wed, Apr 22, priced at $369 found 3 days ago
United
Sat, Apr 11 - Tue, Apr 21
MOB
Mobile
COU
Columbia
$389 Roundtrip, found 3 days ago
$389
Roundtrip
found 3 days ago
Select United flight, departing Sat, Apr 11 from Mobile to Columbia, returning Tue, Apr 21, priced at $389 found 3 days ago
United
Tue, Apr 14 - Wed, Apr 22
MOB
Mobile
COU
Columbia
$400 Roundtrip, found 3 days ago
$400
Roundtrip
found 3 days ago
Select United flight, departing Tue, Apr 14 from Mobile to Columbia, returning Wed, Apr 22, priced at $400 found 3 days ago
United
Sat, Apr 11 - Wed, Apr 22
MOB
Mobile
COU
Columbia
$419 Roundtrip, found 3 days ago
$419
Roundtrip
found 3 days ago
Select United flight, departing Sat, Apr 11 from Mobile to Columbia, returning Wed, Apr 22, priced at $419 found 3 days ago
United
Wed, Apr 15 - Mon, Apr 20
MOB
Mobile
COU
Columbia
$449 Roundtrip, found 3 days ago
$449
Roundtrip
found 3 days ago
Select United flight, departing Wed, Apr 15 from Mobile to Columbia, returning Mon, Apr 20, priced at $449 found 3 days ago
American Airlines
Mon, Apr 13 - Wed, Apr 22
MOB
Mobile
COU
Columbia
$477 Roundtrip, just found
$477
Roundtrip
just found
Select American Airlines flight, departing Mon, Apr 13 from Mobile to Columbia, returning Wed, Apr 22, priced at $477 just found
United
Tue, Apr 14 - Mon, Apr 20
MOB
Mobile
COU
Columbia
$479 Roundtrip, found 3 days ago
$479
Roundtrip
found 3 days ago
Select United flight, departing Tue, Apr 14 from Mobile to Columbia, returning Mon, Apr 20, priced at $479 found 3 days ago
United
Fri, Apr 10 - Tue, Apr 21
MOB
Mobile
COU
Columbia
$485 Roundtrip, found 3 days ago
$485
Roundtrip
found 3 days ago
Select United flight, departing Fri, Apr 10 from Mobile to Columbia, returning Tue, Apr 21, priced at $485 found 3 days ago
American Airlines
Wed, Apr 15 - Fri, Apr 24
MOB
Mobile
COU
Columbia
$499 Roundtrip, found 3 days ago
$499
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Apr 15 from Mobile to Columbia, returning Fri, Apr 24, priced at $499 found 3 days ago

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Frequently asked questions

How much does a flight from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) cost?
Secure a cheap one-way flight from $245 or cheap return flight from $339 from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)?
The cheapest month to fly from MOB to COU is April, when demand is low. Off-peak months are often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from MOB to COU. Then, sort your results by "Price (lowest to highest)" to pick up the best deal available.
How many flights per day from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)?
You'll need to hop on a flight with a layover when traveling from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU). Direct flights don't operate daily on this route. However, simply filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from MOB to COU?
Friday is generally the busiest day for flights, while Tuesday tends to be the quietest.* Remember that flight schedules can vary based on a range of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)?
To avoid potential delays on the Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) route, fly before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU) last-minute?
Booking your plane ticket from MOB to COU just before your journey is typically more expensive. However, if there's some wiggle room with your travel times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a MOB to COU flight and hotel package?
You can save money by securing a MOB to COU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one convenient place. Once you've chosen your ideal accommodations and flights, you can add extras like tours, activities and car rentals.
Can I cancel or change the date of my flight from Mobile Regional Airport (MOB) to Columbia Regional Airport (COU)?
In most instances, you can cancel or modify your MOB to COU flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more information, go to our Customer Service portal.

Travel information

Origin airport
Mobile Regional
Destination airport
Columbia Regional
Roundtrip price
$338
Distance
605 mi

Book with confidence

Mobile to Columbia Flights

The cheapest times to fly from Mobile to Columbia

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Columbia are during the month of April. You can find some of the cheapest flights from Mobile to Columbia with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Columbia

Sunday is one of the best days to book for cheap flights from Mobile to Columbia: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Columbia

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Columbia in 2026. You can also book with separate airlines for your outbound and return journeys, from $245 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Columbia flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Columbia airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Columbia Flights

*Flight schedules are subject to change.

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*Available to One Key members.