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$319 Cheap Flights from Mobile (MOB) to Syracuse (SYR)

View $319 flight on Sat, Oct 10, 2026Opens in a new window

Popular airlines from Mobile Regional Airport (MOB) to Hancock Intl. Airport (SYR)

Cheap Flights from Mobile to Syracuse (MOB-SYR)

Prices were available within the past 7 days and start at $319 for one-way flights and $449 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Sat, Sep 26 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$449 Roundtrip, found 7 hours ago
$449
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Sep 26 from Mobile to Syracuse, returning Wed, Sep 30, priced at $449 found 7 hours ago
United
Sat, Sep 26 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$462 Roundtrip, found 7 hours ago
$462
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Sep 26 from Mobile to Syracuse, returning Wed, Sep 30, priced at $462 found 7 hours ago
United
Tue, Sep 22 - Thu, Oct 1
MOB
Mobile
SYR
Syracuse
$466 Roundtrip, found 7 hours ago
$466
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Sep 22 from Mobile to Syracuse, returning Thu, Oct 1, priced at $466 found 7 hours ago
United
Sat, Sep 26 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$467 Roundtrip, found 7 hours ago
$467
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Sep 26 from Mobile to Syracuse, returning Wed, Sep 30, priced at $467 found 7 hours ago
American Airlines
Sat, Sep 26 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$495 Roundtrip, found 7 hours ago
$495
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Sat, Sep 26 from Mobile to Syracuse, returning Wed, Sep 30, priced at $495 found 7 hours ago
United
Tue, Sep 22 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$503 Roundtrip, found 7 hours ago
$503
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Sep 22 from Mobile to Syracuse, returning Wed, Sep 30, priced at $503 found 7 hours ago
United
Sat, Sep 26 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$504 Roundtrip, found 7 hours ago
$504
Roundtrip
found 7 hours ago
Select United flight, departing Sat, Sep 26 from Mobile to Syracuse, returning Wed, Sep 30, priced at $504 found 7 hours ago
United
Tue, Sep 22 - Thu, Oct 1
MOB
Mobile
SYR
Syracuse
$507 Roundtrip, found 7 hours ago
$507
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Sep 22 from Mobile to Syracuse, returning Thu, Oct 1, priced at $507 found 7 hours ago
United
Tue, Sep 22 - Wed, Sep 30
MOB
Mobile
SYR
Syracuse
$508 Roundtrip, found 7 hours ago
$508
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Sep 22 from Mobile to Syracuse, returning Wed, Sep 30, priced at $508 found 7 hours ago
Delta
Tue, Sep 22 - Thu, Oct 1
MOB
Mobile
SYR
Syracuse
$552 Roundtrip, found 7 hours ago
$552
Roundtrip
found 7 hours ago
Select Delta flight, departing Tue, Sep 22 from Mobile to Syracuse, returning Thu, Oct 1, priced at $552 found 7 hours ago

What you need to know for your flight from Mobile Regional to Hancock Intl.

Mobile (MOB) to Syracuse (SYR) at a glance

Explore a range of airlines offering flights from Mobile Regional Airport (MOB) to Hancock International Airport (SYR) on this domestic short-haul route. Compare choices from various carriers to discover the itinerary that aligns with your budget, schedule, and travel plans as you plan your visit to Syracuse’s renowned attractions and neighborhoods. Get ready for your journey with all the essential details for flights from Mobile to Syracuse.

  • Fastest flight duration: around 3h 45m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 1,100 miles (1,770 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $125–$640, depending on seasonality and how far ahead you book

Flights from Mobile Regional Airport (MOB) to Hancock International Airport (SYR)

According to recent traveler bookings, the top airlines flying from Mobile to Syracuse are favored for their one-stop services, with common layovers at Washington Dulles International Airport (IAD, approximately 1 hour 15 minutes), Charlotte-Douglas International Airport (CLT, about 1 hour 15 minutes), and Hartsfield-Jackson Atlanta International Airport (ATL, roughly 1 hour). These options provide the flexibility to balance price, total travel time, and cabin class to create the best itinerary for your journey.

  • American Airlines: This comprehensive airline provides one-stop service, with one-way ticket prices usually falling between $125 and $615. It is responsible for about 44% of departures on this route, featuring an in-flight duration of 3 hours and 45 minutes and a total travel time of around 5 hours, including layover.
  • United: United Airlines offers one-stop flights, with one-way fares typically ranging from $230 to $650. It covers roughly 37% of departures for this route, with an in-flight time of 3 hours and 45 minutes. The overall journey takes about 5 hours, including layover time.
  • Delta: Delta Airlines provides one-stop service with one-way fares generally priced between $130 and $625. It accounts for approximately 20% of departures along this route, featuring a flight time of 3 hours and 45 minutes, resulting in a total travel duration of roughly 5 hours, layover included.

Alternative routes from Mobile (MOB) to Syracuse (SYR)

  • Pensacola to Syracuse (PNS-SYR): Located approximately 64 miles from Mobile Regional Airport (MOB), Pensacola International Airport (PNS) offers one-way economy fares that generally fall between $125 and $480, influenced by the season and how far in advance you book. Travelers can expect primarily one-stop flights, with common layover points including Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Major airlines operating on this route consist of American Airlines and Delta, with first-class service also available.
  • Gulfport to Syracuse (GPT-SYR): Gulfport - Biloxi International Airport (GPT) is roughly 53 miles from Mobile Regional Airport (MOB). On this route, one-way economy fares usually range from $130 to $400, varying based on the time of year and booking lead time. This route features both one-stop and multi-stop flights, with frequent layovers at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Delta and American Airlines are the leading carriers on this route, which also offers first-class service options.

How to find the best prices for flights from Mobile (MOB) to Syracuse (SYR)

Getting some of the best deals on flights from Mobile to Syracuse is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are often found when booking within two weeks, which coincides with when most travelers make their reservations. Departures in the morning, specifically between 5 AM and 12 PM, typically offer lower prices and are the most popular flight times. Additionally, flying on Wednesday provides both cheaper prices and is recognized as the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Hancock International Airport from Mobile Regional Airport

Syracuse welcomes travelers from Mobile with a range of transport options based on price, convenience, and proximity. Syracuse city center is approximately a 10-minute drive (covering about 8 miles) from Hancock International Airport, depending on traffic. Here's how to reach Syracuse efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Syracuse, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Hancock International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Hancock International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Hancock International Airport, travelers will find the Syracuse Airport Bus Stop, a bus station, just about 0.1 miles away on foot. For those needing train services, the Syracuse Regional Transportation Center, a train station, is located approximately 5.8 miles from the airport by car, while the Syracuse Seaport, a seaport, is around 8.4 miles away by car.

Frequently asked questions

How much does a flight from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) cost?
You can find cheap one-way flights from $319 and cheap return flights from $449 Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) with Expedia. One-way flights generally range between $189 and $694, and roundtrip flights usually range from $345 to $1346. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
The cheapest month to fly from MOB to SYR is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
Enter MOB to SYR and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Mobile, AL (MOB) to Syracuse, NY (SYR), with round-trip tickets starting from around $258 with a layover in Charlotte-Douglas Intl. (CLT). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
To find a cheap flight from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from MOB to SYR. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
The most popular departure times for flights from Mobile, AL (MOB) to Syracuse, NY (SYR) are in the early afternoon, from 12pm to 3pm. About 29% of passengers prefer this time window. Many major carriers, including United Airlines and Delta Air Lines, offer flights during this window. This timing is favored because it allows travelers to start their day in Mobile before heading out.
How long does it take to fly from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
A flight from MOB to SYR with a layover takes around 5 hours, with the route covering approximately 1,087 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
First class seats are offered on the MOB to SYR route with Delta Air Lines and American Airlines.
How do I earn miles on a Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) flight with Expedia?
It's easy to earn miles on a Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Syracuse from Mobile Regional (MOB)?
From Mobile Regional (MOB), you can fly into Hancock Intl. (SYR) to reach Syracuse. Some flights may connect through major hubs like George Bush Intercontinental (IAH), Hartsfield-Jackson Atlanta Intl. (ATL), Washington Dulles Intl. (IAD) before reaching Syracuse. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) at the last minute?
Typically, booking a last minute flight from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package?
Securing a Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.)?
If you booked your Mobile, AL (MOB-Mobile Regional) to Syracuse, NY (SYR-Hancock Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Mobile Regional
Destination airport
Hancock Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$449
Distance
1087 mi

Book with confidence

Mobile to Syracuse Flights

The cheapest times to fly from Mobile to Syracuse

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Mobile to Syracuse are during the month of September. You can find some of the cheapest flights from Mobile to Syracuse with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Mobile to Syracuse

Sunday is one of the best days to book for cheap flights from Mobile to Syracuse: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Mobile to Syracuse

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Mobile to Syracuse in 2026. You can also book with separate airlines for your outbound and return journeys, from $319 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Mobile to Syracuse flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Mobile to Syracuse airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Mobile to Syracuse Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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