$78 Cheap Flights from Myrtle Beach (MYR) to Detroit (DTW)

View $78 flight on Sun, Nov 9, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)

Cheap Flights from Myrtle Beach to Detroit (MYR-DTW)

Prices were available within the past 7 days and start at $78 for one-way flights and $155 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Spirit Airlines
Tue, Oct 7 - Sun, Oct 12
MYR
Myrtle Beach
DTW
Detroit
$155 Roundtrip, found 2 days ago
$155
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, Oct 7 from Myrtle Beach to Detroit, returning Sun, Oct 12, priced at $155 found 2 days ago
Spirit Airlines
Thu, Oct 16 - Sun, Oct 19
MYR
Myrtle Beach
DTW
Detroit
$156 Roundtrip, just found
$156
Roundtrip
just found
Select Spirit Airlines flight, departing Thu, Oct 16 from Myrtle Beach to Detroit, returning Sun, Oct 19, priced at $156 just found
Spirit Airlines
Thu, Oct 2 - Sun, Oct 5
MYR
Myrtle Beach
DTW
Detroit
$159 Roundtrip, found 6 hours ago
$159
Roundtrip
found 6 hours ago
Select Spirit Airlines flight, departing Thu, Oct 2 from Myrtle Beach to Detroit, returning Sun, Oct 5, priced at $159 found 6 hours ago
Spirit Airlines
Wed, Oct 15 - Sun, Oct 19
MYR
Myrtle Beach
DTW
Detroit
$164 Roundtrip, just found
$164
Roundtrip
just found
Select Spirit Airlines flight, departing Wed, Oct 15 from Myrtle Beach to Detroit, returning Sun, Oct 19, priced at $164 just found
Spirit Airlines
Wed, Oct 1 - Sun, Oct 5
MYR
Myrtle Beach
DTW
Detroit
$164 Roundtrip, found 1 hour ago
$164
Roundtrip
found 1 hour ago
Select Spirit Airlines flight, departing Wed, Oct 1 from Myrtle Beach to Detroit, returning Sun, Oct 5, priced at $164 found 1 hour ago
Spirit Airlines
Thu, Oct 23 - Sun, Oct 26
MYR
Myrtle Beach
DTW
Detroit
$167 Roundtrip, found 1 day ago
$167
Roundtrip
found 1 day ago
Select Spirit Airlines flight, departing Thu, Oct 23 from Myrtle Beach to Detroit, returning Sun, Oct 26, priced at $167 found 1 day ago
Southwest Airlines
Wed, Oct 8 - Sun, Oct 12
MYR
Myrtle Beach
DTW
Detroit
$176 Roundtrip, found 5 days ago
$176
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Wed, Oct 8 from Myrtle Beach to Detroit, returning Sun, Oct 12, priced at $176 found 5 days ago
Delta
Fri, Oct 24 - Sun, Oct 26
MYR
Myrtle Beach
DTW
Detroit
$219 Roundtrip, found 2 hours ago
$219
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Oct 24 from Myrtle Beach to Detroit, returning Sun, Oct 26, priced at $219 found 2 hours ago
American Airlines
Thu, Nov 13 - Tue, Nov 18
MYR
Myrtle Beach
DTW
Detroit
$239 Roundtrip, found 3 hours ago
$239
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Thu, Nov 13 from Myrtle Beach to Detroit, returning Tue, Nov 18, priced at $239 found 3 hours ago
United
Tue, Nov 4 - Mon, Nov 17
MYR
Myrtle Beach
DTW
Detroit
$279 Roundtrip, found 7 hours ago
$279
Roundtrip
found 7 hours ago
Select United flight, departing Tue, Nov 4 from Myrtle Beach to Detroit, returning Mon, Nov 17, priced at $279 found 7 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Detroit (DTW)

May is typically the cheapest month to fly

From $72 - $255 per traveler.

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW) cost?
Grab a cheap one-way flight from $78 or cheap return flight from $155 from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
October is the least expensive month to fly from MYR to DTW. Timing your trip outside of the busy season is often the key to better flight prices.
Which airlines fly direct from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
If you're departing from Myrtle Beach Intl. Airport (MYR), you can hop on a nonstop flight to Detroit Metropolitan Wayne County Airport (DTW) with Delta Air Lines.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
To find the cheapest airline that'll fly you from MYR to DTW, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and seat class. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
On average, there is just 1 nonstop flight taking off from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW) every day. If this doesn't suit your schedule, check out flights with a layover. Just filter your search on Expedia to include one or more stops to find the next best option.
What are the most popular departure times for flights from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
Flights between MYR and DTW tend to be busiest at 12 PM. If you're after a more relaxed experience and potentially cheaper fares, choose a time outside the usual busy windows.
What day of the week has the most flights from MYR to DTW?
If you depart on a Friday, you'll get the largest range of choices for flights from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW).
What is the earliest flight from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
The first flight of the day leaving from Myrtle Beach Intl. Airport (MYR) is at around 12:56PM UTC-5. Hop on this flight and you'll arrive at Detroit Metropolitan Wayne County Airport (DTW) at approximately 2:58PM UTC-5. The total time in the air is 2h 2m.
How long does it take to fly from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
The average flight time from MYR to DTW is 2 hours and 2 minutes, covering a total distance of 640 mi.
What airline has the least delays from MYR to DTW?
Aeromexico has the best track record for on-time direct flights from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW), with an on-time rating of 90%. Use the Expedia App to check your flight schedule before you take off and get real-time updates about any trip changes.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
Opt for a flight from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW) that leaves before 3 PM to reduce the likelihood of delays. Departures after this hour are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Detroit from Myrtle Beach Intl. Airport (MYR)?
Detroit Metropolitan Wayne County Airport (DTW) is the only airport in Detroit with direct flights from Myrtle Beach Intl. Airport (MYR). Check out your options and discover affordable fares on Expedia.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW) last-minute?
Last-minute fares from MYR to DTW are usually more expensive. To lock in the lowest rates, start looking for flights as soon as possible. That said, if you can play around with your travel dates, it's possible to find a cheap ticket right before your trip.
Is it cheaper to book a MYR to DTW flight and hotel package?
You can save money by booking a MYR to DTW flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage it all in one place. Once you've chosen your ideal flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Detroit Metropolitan Wayne County Airport (DTW)?
Generally, it's possible to cancel or reschedule your MYR to DTW flight. However, for bookings made more than 24 hours ago, additional fees may apply. Check your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more details on our Customer Service portal.

Travel information

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Detroit Metropolitan Wayne County
Airlines serving
American Airlines, Delta, Southwest Airlines, Spirit Airlines, United
Roundtrip price
$154
Distance
637 mi
Average flight time
1 hour 56 mins

Book with confidence

Book with confidence

Myrtle Beach to Detroit Flights

The cheapest times to fly from Myrtle Beach to Detroit

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Detroit are during the month of October. You can find some of the cheapest flights from Myrtle Beach to Detroit with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Detroit

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Detroit: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Detroit

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Detroit in 2025. You can also book with separate airlines for your outbound and return journeys, from $78 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Detroit flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Detroit airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Detroit Flights

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*Available to One Key members.