$259 Cheap Flights from Portland (PDX) to Medellín (MDE)

View $259 flight on Mon, Jan 12, 2026Opens in a new window

Popular airlines from Portland International Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)

Cheap Flights from Portland to Medellín (PDX-MDE)

Prices were available within the past 7 days and start at $259 for one-way flights and $566 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Mon, Jan 12 - Wed, Jan 21
PDX
Portland
MDE
Medellin
$566 Roundtrip, found 3 hours ago
$566
Roundtrip
found 3 hours ago
Select Alaska Airlines flight, departing Mon, Jan 12 from Portland to Medellin, returning Wed, Jan 21, priced at $566 found 3 hours ago
Alaska Airlines
Mon, Jan 12 - Wed, Jan 21
PDX
Portland
MDE
Medellin
$574 Roundtrip, found 3 hours ago
$574
Roundtrip
found 3 hours ago
Select Alaska Airlines flight, departing Mon, Jan 12 from Portland to Medellin, returning Wed, Jan 21, priced at $574 found 3 hours ago
Alaska Airlines
Fri, Feb 20 - Tue, Feb 24
PDX
Portland
MDE
Medellin
$576 Roundtrip, found 9 hours ago
$576
Roundtrip
found 9 hours ago
Select Alaska Airlines flight, departing Fri, Feb 20 from Portland to Medellin, returning Tue, Feb 24, priced at $576 found 9 hours ago
Alaska Airlines
Sun, Feb 1 - Sat, Feb 7
PDX
Portland
MDE
Medellin
$583 Roundtrip, found 11 hours ago
$583
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Sun, Feb 1 from Portland to Medellin, returning Sat, Feb 7, priced at $583 found 11 hours ago
Alaska Airlines
Sun, Feb 1 - Sat, Feb 7
PDX
Portland
MDE
Medellin
$583 Roundtrip, found 11 hours ago
$583
Roundtrip
found 11 hours ago
Select Alaska Airlines flight, departing Sun, Feb 1 from Portland to Medellin, returning Sat, Feb 7, priced at $583 found 11 hours ago
Alaska Airlines
Thu, Jan 22 - Wed, Jan 28
PDX
Portland
MDE
Medellin
$584 Roundtrip, found 2 hours ago
$584
Roundtrip
found 2 hours ago
Select Alaska Airlines flight, departing Thu, Jan 22 from Portland to Medellin, returning Wed, Jan 28, priced at $584 found 2 hours ago
United
Fri, Nov 7 - Tue, Nov 11
PDX
Portland
MDE
Medellin
$620 Roundtrip, found 22 hours ago
$620
Roundtrip
found 22 hours ago
Select United flight, departing Fri, Nov 7 from Portland to Medellin, returning Tue, Nov 11, priced at $620 found 22 hours ago
Aeromexico
Tue, Mar 10 - Wed, Mar 18
PDX
Portland
MDE
Medellin
$707 Roundtrip, found 1 day ago
$707
Roundtrip
found 1 day ago
Select Aeromexico flight, departing Tue, Mar 10 from Portland to Medellin, returning Wed, Mar 18, priced at $707 found 1 day ago
American Airlines
Wed, Feb 11 - Thu, Feb 19
PDX
Portland
MDE
Medellin
$712 Roundtrip, found 9 hours ago
$712
Roundtrip
found 9 hours ago
Select American Airlines flight, departing Wed, Feb 11 from Portland to Medellin, returning Thu, Feb 19, priced at $712 found 9 hours ago
JetBlue Airways
Fri, May 22 - Sat, May 30
PDX
Portland
MDE
Medellin
$899 Roundtrip, found 10 hours ago
$899
Roundtrip
found 10 hours ago
Select JetBlue Airways flight, departing Fri, May 22 from Portland to Medellin, returning Sat, May 30, priced at $899 found 10 hours ago

Find the cheapest month to fly from Portland (PDX) to Medellín (MDE)

January is typically the cheapest month to fly

From $409 - $1,034 per traveler.

Alternative airports near Medellín

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Jose Maria Cordova Intl. MDE. Cheapest option available. Average driving time to city center is 29 minutes. Flights from $785
MDE
Jose Maria Cordova Intl.
Cheapest
Average driving time to city center29 min
Flights from $785

Frequently asked questions

How much does a flight from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE) cost?
Secure a cheap one-way flight from $259 or cheap return flight from $566 from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)?
January is the most affordable month to fly from PDX to MDE. Timing your trip outside of the busy season is often the key to scoring lower fares.
What is the cheapest airline that flies from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)?
Use the filters on Expedia to compare different airlines and find the cheapest carrier that'll take you from PDX to MDE. Then, sort your results by "Price (lowest to highest)" to score the best deal available.
How many flights per day from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)?
You'll have to take a flight with a layover when traveling from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE). There are no daily direct flights on this route. However, just filter your search to include one or more stops to discover the best option for your trip.
What day of the week has the most flights from PDX to MDE?
Typically you'll find the largest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)?
To avoid potential delays on the Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE) route, aim to fly before 3 PM. Later flights are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE) last-minute?
Booking your plane ticket from PDX to MDE shortly before your journey is generally more expensive. However, if you're flexible with your itinerary, you could snag a cheap last-minute fare.
Is it cheaper to book a PDX to MDE flight and hotel package?
You'll generally save money by securing a PDX to MDE flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've selected your ideal flights and accommodations, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Portland Intl. Airport (PDX) to Jose Maria Cordova Intl. Airport (MDE)?
In most instances, you're able to reschedule or cancel your PDX to MDE flight. However, additional fees may apply, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's fees and guidelines on flight changes, or if you'd like more information, go to our Customer Service portal.

Travel information

Origin airport
Portland Intl.
Destination airport
José María Córdova Intl.
Airlines serving
Aeromexico, American Airlines, Delta, LATAM Airlines Group, United, avianca
Roundtrip price
$566
Distance
3913 mi

Book with confidence

Portland to Medellín Flights

The cheapest times to fly from Portland to Medellín

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Portland to Medellín are during the month of January. You can find some of the cheapest flights from Portland to Medellín with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Portland to Medellín

Sunday is one of the best days to book for cheap flights from Portland to Medellín: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Portland to Medellín

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Portland to Medellín in 2025. You can also book with separate airlines for your outbound and return journeys, from $259 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Portland to Medellín flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Portland to Medellín airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Portland to Medellín Flights

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*Available to One Key members.