$569 Cheap Flights from Roanoke (ROA) to Southampton (SOU)

View $569 flight on Sat, Nov 1, 2025Opens in a new window

Popular airlines from Roanoke Regional Airport (ROA) to Southampton (SOU)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from Roanoke to Southampton (ROA-SOU)

Prices were available within the past 7 days and start at $569 for one-way flights and $1,352 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,352 Roundtrip, found 6 days ago
$1,352
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,352 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,358 Roundtrip, found 6 days ago
$1,358
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,358 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,359 Roundtrip, found 6 days ago
$1,359
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,359 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,365 Roundtrip, found 6 days ago
$1,365
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,365 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,406 Roundtrip, found 6 days ago
$1,406
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,406 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,412 Roundtrip, found 6 days ago
$1,412
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,412 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,412 Roundtrip, found 6 days ago
$1,412
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,412 found 6 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,418 Roundtrip, found 6 days ago
$1,418
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,418 found 6 days ago
Delta
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,500 Roundtrip, found 6 days ago
$1,500
Roundtrip
found 6 days ago
Select Delta flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,500 found 6 days ago
KLM
Wed, Jul 8 - Wed, Jul 22
ROA
Roanoke
SOU
Southampton
$1,552 Roundtrip, found 6 days ago
$1,552
Roundtrip
found 6 days ago
Select KLM flight, departing Wed, Jul 8 from Roanoke to Southampton, returning Wed, Jul 22, priced at $1,552 found 6 days ago

Frequently asked questions

How much does a flight from Roanoke Regional Airport (ROA) to Southampton Airport (SOU) cost?
Secure a cheap one-way flight from $569 or cheap return flight from $1,352 from Roanoke Regional Airport (ROA) to Southampton Airport (SOU) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Roanoke Regional Airport (ROA) to Southampton Airport (SOU)?
July is the most affordable month to fly from ROA to SOU. Traveling outside of peak seasons is often the key to finding a great deal.
What is the cheapest airline that flies from Roanoke Regional Airport (ROA) to Southampton Airport (SOU)?
Expedia's filter tool lets you easily compare different airlines, travel time and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest ROA to SOU flight.
How many flights per day from Roanoke Regional Airport (ROA) to Southampton Airport (SOU)?
There are no daily direct flights from Roanoke Regional Airport (ROA) to Southampton Airport (SOU). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from ROA to SOU?
Typically you'll find the greatest selection of flight options on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Roanoke Regional Airport (ROA) to Southampton Airport (SOU)?
To land at Southampton Airport (SOU) without delays, select a flight that leaves from Roanoke Regional Airport (ROA) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Roanoke Regional Airport (ROA) to Southampton Airport (SOU) last-minute?
Booking your flight from ROA to SOU shortly before your getaway is usually more expensive. But if you're flexible with your travel dates and times, you could snag a cheap last-minute fare.
Is it cheaper to book a ROA to SOU flight and hotel package?
You'll typically save money by booking a ROA to SOU flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. After choosing your ideal flights and accommodations, consider adding extras such as tours, activities and car rentals.
Can I cancel or change the date of my flight from Roanoke Regional Airport (ROA) to Southampton Airport (SOU)?
If you booked your ROA to SOU flight within the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of fare you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal for further details.

Travel information

Origin airport
Roanoke Regional
Destination airport
Southampton
Roundtrip price
$1,351
Distance
3818 mi

Book with confidence

Roanoke to Southampton Flights

The cheapest times to fly from Roanoke to Southampton

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Roanoke to Southampton are during the month of July. You can find some of the cheapest flights from Roanoke to Southampton with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Roanoke to Southampton

Sunday is one of the best days to book for cheap flights from Roanoke to Southampton: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Roanoke to Southampton

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Roanoke to Southampton in 2025. You can also book with separate airlines for your outbound and return journeys, from $569 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Roanoke to Southampton flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Roanoke to Southampton airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Roanoke to Southampton Flights

Explore a world of travel with Expedia

*Available to One Key members.