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$117 Cheap Flights from Louisville (SDF) to Greenville (GSP)

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Cheap Flights from Louisville to Greenville (SDF-GSP)

Prices were available within the past 7 days and start at $117 for one-way flights and $233 for roundtrip, for the period specified. Prices and availability are subject to change.

Alternative airports near Greenville

Prices were available within the past 7 days. Prices and availability are subject to change.

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Louisville (SDF) to Greenville (GSP) at a glance

Travel from Louisville (SDF) to Greenville (GSP) with a variety of airlines on this domestic short-haul route. Discover options for cheap flights from Louisville and compare the best choices for your budget and schedule, whether you prefer full-service or low-cost carriers. As you plan your visit to explore Greenville’s notable attractions and neighborhoods, find essential information on Louisville to Greenville airfare to help you secure the ideal itinerary for your trip.

  • Fastest flight duration: around 2h 30m in-flight, plus roughly 1 hour layover with one stop
  • Route distance: roughly 300 miles (485 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $115–$395, depending on seasonality and how far ahead you book

Flights from Louisville International Airport (SDF) to Greenville-Spartanburg International Airport (GSP)

Recent traveler bookings reveal the top airlines flying from Louisville to Greenville, often favored for their one-stop services. Common layover points include Hartsfield-Jackson Atlanta International Airport (ATL) with approximately a 1 hour 15 minute layover, Charlotte-Douglas International Airport (CLT) with about a 1 hour layover, and Baltimore Washington International Thurgood Marshall Airport (BWI), also around 1 hour 15 minutes. This variety allows you to compare prices, total travel times, and cabin classes to find the most suitable itinerary for your journey.

  • American Airlines: This major carrier provides full-service one-stop flights, with one-way ticket prices generally falling between $115 and $380. It holds about 44% of the departures for this route, featuring an in-flight duration of 2 hours and 30 minutes, and an overall travel time of approximately 3 hours and 45 minutes, including layovers.
  • Delta: Another prominent full-service airline, Delta offers one-stop service with one-way fares typically priced from $115 to $405. It represents around 39% of the flights on this route, with a flight time of 2 hours and 30 minutes and a total journey duration of about 3 hours and 45 minutes, factoring in layovers.
  • Southwest Airlines: Known as a budget-friendly option, Southwest Airlines provides one-stop service with one-way fares usually ranging from $115 to $395. This airline accounts for roughly 10% of the departures on this route, featuring a flight time of 2 hours and 30 minutes and an entire journey time of approximately 3 hours and 45 minutes, including layover periods.
  • United: A well-established full-service airline, United offers one-stop flights with one-way prices typically between $150 and $510. It makes up about 7% of the departures for this route, with an in-flight duration of 2 hours and 30 minutes and a total travel time around 3 hours and 45 minutes, including any layovers.

Best time to fly from Louisville (SDF) to Greenville (GSP)

The most popular months for travelers flying from Louisville to Greenville are February, March, and April, when peak temperatures in Greenville reach up to 59.9°F in April. If you prefer quieter travel, consider July, the least busy time to visit with temperatures around 79.5°F and typically the lowest average one-way fare (around $212). Flight availability peaks in July, with approximately 10 flights per week, making it easier to find convenient departure times. September and November have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: July usually offers good deals with average one-way fare around $212, roughly 16% cheaper than the yearly average.
  • More budget-friendly months to fly: September and January typically offer average one-way fares of around $232.
  • Most flight options: July has the highest number of flights from Louisville to Greenville, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
MonthTemperatureDemandWeekly FlightsAverage one-way Fare
January41.4°F (5.2°C)Average8$233
February45.3°F (7.4°C)High9$242
March51.8°F (11.0°C)High9$252
April59.9°F (15.5°C)High9$269
May68.4°F (20.2°C)Average9$291
June76.1°F (24.5°C)Average8$258
July79.5°F (26.4°C)Low10$212
August77.5°F (25.3°C)Low8$278
September72.3°F (22.4°C)Average7$232
October61.9°F (16.6°C)Average9$256
November51.1°F (10.6°C)Average7$263
December45.3°F (7.4°C)Low8$247

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Louisville (SDF) to Greenville (GSP)

  • Louisville to Greenville (SDF-GMU): Greenville Downtown Airport (GMU) is located approximately 8 miles from Greenville-Spartanburg International Airport (GSP).

How to find the best prices for flights from Louisville (SDF) to Greenville (GSP)

Getting some of the best deals on flights from Louisville to Greenville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, although most travelers tend to book within 2 weeks. Afternoon departures from 12 p.m. to 6 p.m. often offer lower prices, while morning flights from 5 a.m. to 12 p.m. are the most popular. Additionally, flying on Wednesday typically provides better prices, despite Thursday being the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Greenville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Greenville-Spartanburg International Airport from Louisville International Airport

Greenville welcomes travelers from Louisville with a range of transport options based on price, convenience, and proximity. Greenville city center is approximately a 20-minute drive (covering about 16 miles) from Greenville-Spartanburg International Airport, depending on traffic. Here's how to reach Greenville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Greenville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Greenville-Spartanburg International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Greenville-Spartanburg International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.

Louisville to Greenville Flights

The cheapest times to fly from Louisville to Greenville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Louisville to Greenville are during the month of November. You can find some of the cheapest flights from Louisville to Greenville with Expedia's search tool and vast selection of airlines.

The best time to book a flight from Louisville to Greenville

Sunday is one of the best days to book for cheap flights from Louisville to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

How to find cheap round-trip tickets from Louisville to Greenville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Louisville to Greenville in 2026. You can also book with separate airlines for your outbound and return journeys, from $117 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Louisville to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

You could also save big by booking one of Expedia's vacation packages. Bundling together your Louisville to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

*Terms apply.

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

Frequently Asked Questions

How much does a flight from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) cost?

You can find cheap one-way flights from $117 and cheap return flights $233 Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) with Expedia. One-way flights typically cost between $194 and $549, and return flights often range between $302 and $860. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) ticket fares go up or down.

*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.

What is the cheapest month to fly from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

January is the cheapest month to fly from Louisville to Greenville, with average return fares around $256. This is about 34% lower than the average price throughout the year, as January often has reduced travel demand. Other cheap months to fly from Louisville to Greenville include February and October.

*Averages based on flights available on Expedia in the last year.

Which airlines fly direct from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Enter SDF to GSP and your travel dates, then apply the 'Nonstop' filter to see only direct flights.

How do I find cheap flights from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

To find a cheap flight from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.

What is the best time to fly from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

For flights from Louisville, KY (SDF) to Greenville, SC (GSP), January and February are the best months to fly. You can find return flights for around $256, making these months quite economical. January is typically quieter, allowing for a more relaxed travel experience, while February offers a chance to enjoy the early signs of spring.

*Prices based on flights available on Expedia in the last year.

What is the earliest flight from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

The earliest flight from Louisville, KY (SDF) to Greenville, SC (GSP) usually leaves at 5:00 AM, operated by American Airlines. This service is seasonal, active in January and December, and an early start can help you make the most of your day in Greenville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.

How long does it take to fly from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

A flight from SDF to GSP with a layover takes around 6 hours, with the route covering approximately 300 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.

Can you fly business or first class from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

Select the "Business class" and "First class" filters when looking for SDF to GSP flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.

How do I earn miles on a Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight with Expedia?

It's easy to earn miles on a Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

What airports do you fly into for Greenville from Louisville Intl. (SDF)?

From Louisville Intl. (SDF), you can fly into Pitt-Greenville (PGV) and Greenville-Spartanburg Intl. (GSP) in Greenville. Compare routes and airports on Expedia to find the best flight options for your travel plans.

Is it cheaper to buy a plane ticket from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) at the last minute?

Typically, booking a last minute flight from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.

Is it cheaper to book a Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package?

Securing a Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.

Can I cancel or change the date of my flight from Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.)?

If you booked your Louisville, KY (SDF-Louisville Intl.) to Greenville, SC (GSP-Greenville-Spartanburg Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Louisville Intl. Airport
Destination airport
Greenville-Spartanburg Intl. Airport
Distance
300 miles away
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Popular airline
American Airlines
Roundtrip price
$233
*Available to One Key members.