$540 Cheap Flights from Sao Luis (SLZ) to Houston (HOU)

View $540 flight on Mon, Feb 23, 2026Opens in a new window

Popular airlines from Sao Luis (SLZ-Marechal Cunha Machado Intl.) to Houston William Hobby Airport (HOU)

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Cheap Flights from Sao Luis to Houston (SLZ-HOU)

Prices were available within the past 7 days and start at $540 for one-way flights and $1,226 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,226 Roundtrip, found 17 hours ago
$1,226
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,226 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,240 Roundtrip, found 17 hours ago
$1,240
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,240 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,262 Roundtrip, found 17 hours ago
$1,262
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,262 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,330 Roundtrip, found 17 hours ago
$1,330
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,330 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,356 Roundtrip, found 17 hours ago
$1,356
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,356 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,359 Roundtrip, found 17 hours ago
$1,359
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,359 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,371 Roundtrip, found 17 hours ago
$1,371
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,371 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,374 Roundtrip, found 17 hours ago
$1,374
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,374 found 17 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,381 Roundtrip, found 17 hours ago
$1,381
Roundtrip
found 17 hours ago
Select LATAM Airlines Group flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,381 found 17 hours ago
GOL Linhas Aereas S.A.
Mon, Sep 1 - Sat, Nov 1
SLZ
São Luís
IAH
Houston
$1,404 Roundtrip, found 17 hours ago
$1,404
Roundtrip
found 17 hours ago
Select GOL Linhas Aereas S.A. flight, departing Mon, Sep 1 from São Luís to Houston, returning Sat, Nov 1, priced at $1,404 found 17 hours ago
Flights from Sao Luis (SLZ) to Houston (IAH)
Origin airport
Marechal Cunha Machado Intl.
Destination airport
George Bush Intercontinental
Roundtrip price
$1,225
Distance
4049 mi

Sao Luis to Houston Flights

The cheapest times to fly from Sao Luis to Houston

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sao Luis to Houston are during the month of September. You can find some of the cheapest flights from Sao Luis to Houston with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sao Luis to Houston

Sunday is one of the best days to book for cheap flights from Sao Luis to Houston: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sao Luis to Houston

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sao Luis to Houston in 2025. You can also book with separate airlines for your outbound and return journeys, from $540 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sao Luis to Houston flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sao Luis to Houston airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU) cost?
Discover the latest flight deals from SLZ to HOU by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from SLZ to HOU?
The cheapest flights from SLZ to HOU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from SLZ to HOU?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from SLZ to HOU. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU)?
You'll need to take a flight with a layover when traveling from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to discover an option that works for you.
What day of the week has the most flights from SLZ to HOU?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Keep in mind that flight schedules can vary depending on various factors, such as the airline and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU)?
Opt for a flight from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU) last-minute?
Last-minute bookings from SLZ to HOU are usually more expensive. To lock in the lowest rates, start searching for flights early. That said, if your travel plans are flexible, it's possible to find a cheap fare right before your journey.
Is it cheaper to book a SLZ to HOU flight and hotel package?
You can save money by booking a SLZ to HOU flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've chosen your preferred accommodations and flights, consider adding extras like car rentals, tours and activities.
Can I cancel or change the date of my flight from Marechal Cunha Machado Intl. Airport (SLZ) to William P. Hobby Airport (HOU)?
Usually, it's possible to cancel or reschedule your SLZ to HOU flight. However, if it's been more than 24 hours since booking, additional charges may apply. Check your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find further details on our Customer Service portal.

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*Available to One Key members.