Southern Minnesota Romantic Vacations

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4 Night Romantic vacations in Southern Minnesota

Price found within the past 48 hours. Click for updated prices.
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

$553
per person
Oct 20 - Oct 23
found 17 hours ago
Roundtrip flight included
Seattle (SEA) to Rochester (RST)
8/10 Very Good! (1,001 reviews)
Kahler Grand Hotel

Kahler Grand Hotel

Downtown Rochester
$690
per person
Oct 20 - Oct 23
found 17 hours ago
Roundtrip flight included
Seattle (SEA) to Rochester (RST)
8.4/10 Very Good! (2,293 reviews)
We have to visit the Mayo frequently and this was the first time staying at this hotel. The room was a bit small but served our needs. Very clean and well maintained. Perfect location for the Mayo clinic appointment with the ability to park the car in the ramp and walk to everything we needed. Connected to the subway system, many restaurants and shops in the area.

Reviewed on Sep 18, 2026

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How to find a romantic Southern Minnesota vacation

How can I find the best Southern Minnesota vacation packages for couples?

To win over the love of your life, first choose where and when you want to bring the romance. Now flirt with the filters to add ocean views, spa, pools, and anything else that gets your heart racing.

How can I find cheap Southern Minnesota romantic packages for two?

For dollar-friendly delights, sort your search results by price or deals. You can also filter by budget to find romantic retreats at prices you’ll love. For an affordable and alluring adventure, try self-catering and visiting outside busy months of .

How can I plan a great romantic trip to Southern Minnesota?

Find what fills you with joy and dive right in, whether you thrill in a little adventure or lust for long lazy days by the pool, handcrafted cocktails in hand. Fire cupid’s arrow at our filters and build your dream trip for two.

How much is a trip for two to Southern Minnesota?

Put a price on love with stunning deals for duos starting at just $553. Stay during the quiet season, in , for breaks to make your bank balance smile. Prices and availability are subject to change. Additional terms may apply.

Can I book Southern Minnesota spa packages for couples?

Check the filter box for a seductive stay at a spa. Sort your results by price, deals, rating, and more to guarantee the perfect match.

What’s the best time of year for a romantic vacation in Southern Minnesota?

Book your romantic getaway during the quieter months of when you can have the place to yourself, pretty much. To show your partner off to the world, provide a more abundant audience.

How can I book romantic weekend getaway packages in Southern Minnesota?

To book a loved-up break in Southern Minnesota, enter your travel dates and sort by price, deals, rating—whatever matters most to you and your partner. Now, you can add some adult-only amenities, like a hot tub or full-service spa for total R, R, & R (that’s romance, rest, and recuperation).

Can I book a romantic trip to Southern Minnesota with free cancellation and/or flexible dates?

The course of true love should always run smooth, but we get that there are hiccups. So, filter by payment option to search for romantic stays with free cancellation and buy now, pay later options.

Why should I book my Southern Minnesota romantic holiday with Expedia?

If you’ve only got eyes for excellent escapes, book your loved-up break with Expedia. Fling the filters to find accommodation you’ll adore. And what’s more attractive than ATOL protection?

Top Romantic Southern Minnesota Hotels

Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN
  • 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.
9.8/10 Exceptional! (550 reviews)
"Personal attention from owners. Nightcap aperitif & chocolate, 5 course breakfast"

Reviewed on Sep 18, 2026

Alexander Mansion Bed and Breakfast
St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN
  • 2 hours drive from Mayo Clinic
If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...
9.2/10 Wonderful! (1,004 reviews)

Couples like: full-service spa, bar

Travelers say...
"Great location & and elegant hotel"

Reviewed on Sep 15, 2026

St James Hotel, a Historic Hotel of America
AmericInn by Wyndham Austin

AmericInn by Wyndham Austin

1700 8th St NW Austin MN
  • 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.
8.8/10 Excellent! (798 reviews)
"Breakfast was meh"

Reviewed on Sep 16, 2026

AmericInn by Wyndham Austin
See all 1,228 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.