Find 4 Star Hotels in Clayton, MO from $101
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Compare Clayton 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Live by Loews - St.Louis
Moonrise Hotel
21C Museum Hotel St Louis
AC Hotel St. Louis Central West End
Angad Arts Hotel
River City Casino & Hotel
The Royal Sonesta Chase Park Plaza St. Louis
Le Méridien St. Louis Clayton
The Pennywell St.Louis Downtown, a Hilton Hotel
Hotel Saint Louis, Autograph Collection
Hilton St. Louis Frontenac
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Hyatt Regency St. Louis at The Arch
The Last Hotel
The Westin St. Louis
The Cheshire
DoubleTree by Hilton St. Louis Forest Park
Embassy Suites by Hilton St. Louis Downtown
Renaissance St. Louis Airport Hotel
Explore similar 5-star hotels
Four Seasons Hotel St Louis
The beginning of any trip gets started with picking a fantastic spot. Clayton has become a popular local with guests because of all its local amenities. However, "location, location, location" applies to more than just what city where your plane lands. When you want a holiday that is great from start to finish, you need the ideal hotel.
Hotels as Picturesque as Clayton
Clayton saw its fair share of visitors in the last year. Our comment section provides tips and tricks on which hotel will fulfill your wishes for an unbelievable vacation. The resorts found here aim to make your vacation as pleasant as your evenings spent hanging out in Clayton. These hotels aim to make their facilities and grounds pleasing from the time you step onto the property. You'll never have to venture far to sustain your exercise schedule, enjoy an energizing spa treatment, or find a delicious lunch during your vacation with all that they offer.
Rooms have been designed to keep you as cozy as possible, with amenities like in-room tea or coffee, specially designed bathroom products, and, premium bedding. So, lay back and unwind. Moreover, if you find that you're need of anything more, you can be confident the staff will do their best to ensure you continue to be pleased during your time. These hotels are so nice that you'll regret the day you have to check-out.
Reserve a 4-Star Hotel in Clayton Today!
A getaway to Clayton should be one where you don't have to concern yourself about the little things. Expedia can get great rates on world-class accommodations to take your trip to the next level.
Frequently asked questions
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Clayton Hotels by Star Rating
Hotels in Clayton Neighborhoods
Stay near popular Clayton attractions
- Chapel of St. Timothy And St. Titus
- St. Louis Union Station
- Busch Stadium
- Gateway Arch
- St. Louis Zoo
- Washington University in St. Louis
- Forest Park
- Enterprise Center
- Hollywood Casino Amphitheatre
- City Museum
- Barnes Jewish Hospital
- Ameristar Casino St. Charles
- Dome at America’s Center
- Magic House - St. Louis Children's Museum
- St. Louis University
- Mississippi River
- Westport Plaza
- America's Center Convention Complex
- Fox Theater
- Hollywood Casino
More Hotel Options in Clayton
- Boutique Hotels (3)
- Business Hotels (5)
- Cheap Hotels (3)
- Family Hotels (5)
- Golf Hotels (5)
- Historic Hotels (5)
- Hotel Wedding Venues (4)
- Hotel with a Concierge (4)
- Hotels & Resorts for Couples (5)
- Hotels with Air Conditioning (5)
- Hotels with Balconies (3)
- Hotels with Bars (5)
- Hotels with Connecting Rooms (5)
- Hotels with Free Airport Shuttle (1)
- Hotels with Free Breakfast (4)
- Hotels with Free Parking (2)
- Hotels with Free Wifi (4)
- Hotels with Hot Tubs (4)
- Hotels with Laundry Facilities (4)
- Hotels with Restaurants (5)
- Hotels with Room Service (4)
- Hotels with a Gym (4)
- Hotels with a Pool (4)
- Hotels with a View (4)
- Hotels with an Indoor Pool (3)
- Hotels with an Outdoor Pool (4)
- Luxury Hotels (4)
- Non-Smoking Hotels (3)
- Pet-friendly Hotels (3)
- Quiet Resorts & Hotels (1)
- Resorts & Hotels with Spas (3)
- Romantic Hotels (4)
More Popular Hotels in St. Louis
- Best Western St. Louis-Kirkwood Route 66
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- Sonesta ES Suites St. Louis - Chesterfield
- Hilton St. Louis at the Ballpark
- Casino Queen Hotel
- 21C Museum Hotel St Louis
- Moonrise Hotel
- Angad Arts Hotel
- Hilton St. Louis Airport
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Live by Loews - St.Louis
- Wingate by Wyndham St. Louis Airport
- Forest Park Hotel by MDR
- Drury Inn & Suites St. Louis Union Station
- Renaissance St. Louis Airport Hotel
- River City Casino & Hotel
- The Wildwood Hotel
- Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
- Aviator Hotel & Suites South I-55, BW Signature Collection