Find 5 Star Hotels in James Island, SC
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Compare James Island 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
The Sanctuary at Kiawah Island Golf Resort
James Island Five Star Hotel Information
If you’re searching for the celebrity treatment, the 5 star hotels in James Island are your dreams come true. From sprawling resorts to fancy hot spots, theseJames Island 5 star hotels immerse each traveler in the most elite experience money can buy. Want to unwind with a VIP-worthy spa treatment? These hotels have the leisure you're looking for.
Interested in sampling world-class cuisine? The on-site restaurants at the 5 stars hotels in James Island, Charleston, let you do just that. You’ll even be able to book a room (or perhaps a penthouse?) at first-rate hotels near the region’s can’t-miss sights and most bustling shopping centers. Plus, many globe-trotters who visit James Island five star hotels find incredible rates and deep discounts thanks to Expedia, so you can score a deal without sacrificing an ounce of quality.
Everything you could possibly want (and a few things you didn’t know you needed): That’s what you’ll receive when you stay at James Island 5 star hotels.
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Hotels in James Island Neighborhoods
Stay near popular James Island attractions
- James Island County Park
- Battery Number 5 Marker
- Splash Zone Waterpark
- Harbor View Shopping Center
- Fort Lamar Historic Preserve
- Charleston Municipal Golf Course
- Stephen Washington Park
- Tidal Trails
- Port of Charleston Cruise Terminal
- College of Charleston
- Charleston City Market
- Waterfront Park
- Patriots Point
- Medical University of South Carolina
- South Carolina Aquarium
- Joint Base Charleston
- Wild Dunes Resort Golf Course
- North Charleston Coliseum and Performing Arts Center
- USS Yorktown
- Front Beach
More Hotel Options in James Island
- Beach Hotels (2)
- Family Hotels (2)
- Historic Hotels (2)
- Hotels & Resorts for Couples (3)
- Hotels with Air Conditioning (5)
- Hotels with Free Parking (1)
- Hotels with Free Wifi (1)
- Hotels with Laundry Facilities (1)
- Hotels with Restaurants (1)
- Hotels with a Gym (1)
- Non-Smoking Hotels (5)
- Pet-friendly Hotels (1)
- Resorts & Hotels with Spas (1)
- Romantic Hotels (2)
More Accommodation Types in James Island
- Vacation Homes in James Island (931)
- Condo Rentals in James Island (299)
- Apartments in James Island (157)
- Villas in James Island (138)
- Cottages in James Island (56)
- B&B in James Island (21)
- Guest Houses in James Island (20)
- Aparthotels in James Island (10)
- Motels in James Island (10)
- Resorts in James Island (6)
- Houseboats in James Island (4)
- Inns in James Island (2)
- Farmstay in James Island (1)
- Cabin Rentals in James Island (1)
- Condo Resorts in James Island (1)
Explore more hotels
- Hotel Indigo Mount Pleasant, an IHG Hotel
- Quality Inn Mt. Pleasant - Charleston
- Mills House Charleston, Curio Collection by Hilton
- Town & Country Inn and Suites
- The Vendue
- The Beach Club at Charleston Harbor Resort and Marina
- The Palms Oceanfront Hotel
- Tides Folly Beach Hotel
- Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
- Comfort Inn Downtown Charleston
- Charleston Marriott
- Andrew Pinckney Inn
- Cambria Hotel Mount Pleasant – Charleston
- Moxy Charleston Downtown
- Hampton Inn Charleston-Historic District
- Cambria Hotel Charleston Riverview
- Wingate by Wyndham Charleston Coliseum
- Tru by Hilton Mt Pleasant Charleston
- Hyatt Place Charleston/Historic District
- Charleston Creekside Inn