Find all hotels by Independent in Cairo, IL from $69
Most hotels are fully refundable. Because flexibility matters.
Save 10% or more on over 100,000 hotels worldwide as a One Key member.
Search over 2.9 million properties and 550 airlines worldwide.
Compare rooms and suites by Independent in Cairo with rates, reviews, and availability. Most hotels are fully refundable.
Charming cottage overlooking Lake Acre
Charming Home just minutes from Interstate and Mall
Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286
Standalone Carriage House, 2 BR, 4 Guests, less than one mile from I-57
Beautiful newly renovated farm house overlooking 5 acre lake. ****New Rates ***
Cozy cabins on beautiful Horseshoe Lake
Upscale & Quiet Paducah Retreat on 15 Acres!
The Rested Duck Mallard Room
Beautiful Cabin Retreat
Eagle Inn Charleston
Independent Cairo Hotel Guide
Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Cairo, Illinois. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Cairo hotels guarantees an unparalleled level of comfort and quality.
You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Cairo Independent locations may even offer extra little benefits and discounts for frequent travelers.
Recent reviews of Cairo hotelsExpedia verified reviews
Hotels near popular Cairo Attractions
- Hotels near Fort Defiance State Park
- Hotels near Shawnee National Forest
- Hotels near Mississippi River
- Hotels near Ohio River
- Hotels near Columbus-Belmont State Park
- Hotels near Henry N Barkhausen Cache River Wetlands Center
- Hotels near Shawnee Community College
- Hotels near Mound City National Cemetery
- Hotels near Ballard Wildlife Management Area
- Hotels near Ullin City Hall
More Accommodation Types in Cairo
- Vacation Homes (1,579)
- Apartments (458)
- Motels (226)
- Cabin Rentals (166)
- Cottages (160)
- Condo Rentals (123)
- B&B (76)
- Guest Houses (63)
- Aparthotels (57)
- RV Parks (35)
- Villas (31)
- Farmstay (22)
- Resorts (11)
- Lodges (10)
- Inns (8)
- Hostels (4)
- Chalets (3)
- Castles (2)
- Country Houses (1)
- Holiday Park Resorts (1)
- Residences (1)
More Popular Hotels in Illinois
- La Center Motel
- Eagle Inn Charleston
- Standalone Carriage House, 2 BR, 4 Guests, less than one mile from I-57
- Beautiful newly renovated farm house overlooking 5 acre lake. ****New Rates ***
- Upscale & Quiet Paducah Retreat on 15 Acres!
- Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.