Photo by Jessica King
Find All De Soto Hotels
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Find All De Soto Hotels
We have found 139 De Soto Hotels
- Cabin Springs. Escape to the quiet country. Fish, hike, kayak, see the stars.
- Pear Tree Inn St. Louis Arnold
- Baymont Inn and Suites by Wyndham Farmington, MO
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Drury Inn & Suites St. Louis Arnold
- Comfort Inn Festus - St Louis South
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
- WoodSpring Suites St. Louis Arnold
- Quality Inn & Suites Arnold - St Louis
- Super 8 by Wyndham Farmington
- Quality Inn Farmington
- Quality Inn Festus
- Super 8 by Wyndham Potosi
- Hampton Inn Farmington
- Super 8 by Wyndham Bonne Terre
- Crown Pointe Lodge, BW Signature Collection
- Holiday Inn Express & Suites Farmington, an IHG Hotel
- Motel 6 Bonne Terre, MO
- The Conner House B&B
- The Queen Bee Farm Stay/Hot tub
- Funks Inn, a post civil war era home restored as it was in 1870.
- Private getaway on 4 acres-Close to lots of outdoor activities!
- Rosener's Inn and banquet center
- Corner George Inn Bed & Breakfast
- Bluebird Meadows W/hot Tub and Pool Special
- Super 8 by Wyndham Pevely
- Old Caledonian Bed and Breakfast
Let Expedia take you to the best Hotels in De Soto. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.