Cheap Flights to Plzen Region from $38

View $38 flight on Sun, Apr 26, 2026Opens in a new window

Popular airlines to Plzen Region

  • Lufthansa

  • British Airways

  • KLM

  • Swiss International Air Lines

  • Air France

  • SAS

  • Austrian Airlines

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

How much is the cheapest flight to Plzen Region?

Prices were available within the past 7 days and start at $38 for one-way flights and $94 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Ryanair
Wed, Mar 4 - Wed, Mar 18
MAD
Madrid
PRG
Prague
$94 Roundtrip, found 18 hours ago
$94
Roundtrip
found 18 hours ago
Select Ryanair flight, departing Wed, Mar 4 from Madrid to Prague, returning Wed, Mar 18, priced at $94 found 18 hours ago
Iberia
Wed, May 6 - Sat, May 9
MAD
Madrid
PRG
Prague
$139 Roundtrip, found 13 hours ago
$139
Roundtrip
found 13 hours ago
Select Iberia flight, departing Wed, May 6 from Madrid to Prague, returning Sat, May 9, priced at $139 found 13 hours ago
Smartwings
Thu, Jan 29 - Fri, Jan 30
MAD
Madrid
PRG
Prague
$213 Roundtrip, found 1 hour ago
$213
Roundtrip
found 1 hour ago
Select Smartwings flight, departing Thu, Jan 29 from Madrid to Prague, returning Fri, Jan 30, priced at $213 found 1 hour ago
Brussels Airlines
Wed, Jun 3 - Mon, Jun 8
MAD
Madrid
PRG
Prague
$215 Roundtrip, found 3 days ago
$215
Roundtrip
found 3 days ago
Select Brussels Airlines flight, departing Wed, Jun 3 from Madrid to Prague, returning Mon, Jun 8, priced at $215 found 3 days ago
Swiss International Air Lines
Fri, Feb 27 - Sun, Mar 1
MAD
Madrid
PRG
Prague
$216 Roundtrip, found 3 hours ago
$216
Roundtrip
found 3 hours ago
Select Swiss International Air Lines flight, departing Fri, Feb 27 from Madrid to Prague, returning Sun, Mar 1, priced at $216 found 3 hours ago
KLM
Sun, Feb 8 - Thu, Feb 12
MAD
Madrid
PRG
Prague
$217 Roundtrip, found 1 day ago
$217
Roundtrip
found 1 day ago
Select KLM flight, departing Sun, Feb 8 from Madrid to Prague, returning Thu, Feb 12, priced at $217 found 1 day ago
Lufthansa
Thu, Feb 19 - Sat, Feb 21
MAD
Madrid
PRG
Prague
$223 Roundtrip, found 3 hours ago
$223
Roundtrip
found 3 hours ago
Select Lufthansa flight, departing Thu, Feb 19 from Madrid to Prague, returning Sat, Feb 21, priced at $223 found 3 hours ago
Air France
Sun, Feb 8 - Thu, Feb 12
MAD
Madrid
PRG
Prague
$226 Roundtrip, found 1 day ago
$226
Roundtrip
found 1 day ago
Select Air France flight, departing Sun, Feb 8 from Madrid to Prague, returning Thu, Feb 12, priced at $226 found 1 day ago
Air Serbia
Wed, Dec 2 - Tue, Dec 8
MAD
Madrid
PRG
Prague
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Air Serbia flight, departing Wed, Dec 2 from Madrid to Prague, returning Tue, Dec 8, priced at $253 found 3 days ago
LOT-Polish Airlines
Sat, Jul 11 - Wed, Jul 15
MAD
Madrid
PRG
Prague
$265 Roundtrip, found 1 day ago
$265
Roundtrip
found 1 day ago
Select LOT-Polish Airlines flight, departing Sat, Jul 11 from Madrid to Prague, returning Wed, Jul 15, priced at $265 found 1 day ago

Airports in Plzen Region

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Vaclav Havel PRG. Cheapest option available. Flights from $1,145
PRG
Vaclav Havel
Cheapest
Flights from $1,145

Enjoy extra legroom, flight flexibility, and a seamless travel experience.

*Flight schedules are subject to change.

*Flight schedules are subject to change.

Trending flights to Plzen Region

These prices were available within the past 7 days. Prices quoted are per person, round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Condor
Mon, Apr 13 - Mon, Apr 27
JFK
New York
PRG
Prague
$370 Roundtrip, found 1 day ago
$370
Roundtrip
found 1 day ago
Select Condor flight, departing Mon, Apr 13 from New York to Prague, returning Mon, Apr 27, priced at $370 found 1 day ago
*Available to One Key members.