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Our top choices for Clayton hotels

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien
3.0 star property
Prairie Du Chien
8.0 out of 10, Very Good, (624 reviews)
"Friendly reception and clean and quiet stay."
United States
Penny
27 days ago
$80 nightly
The price is $89
Jun 21 - Jun 22
Total with taxes and fees
AmericInn by Wyndham Prairie du Chien

Windsor Place Inn

Windsor Place Inn
2.0 star property
Southside
8.4 out of 10, Very Good, (1,003 reviews)
"Helpful cheerful staff. Excellent property with nice clean rooms. Excellent weekend breakfast with biscuits."
United States
James
7 days ago
$68 nightly
The price is $75
Jun 16 - Jun 17
Total with taxes and fees
Windsor Place Inn

Waterfront Hotel

Waterfront Hotel
3.0 star property
Prairie Du Chien
9.2 out of 10, Wonderful, (931 reviews)
"Great location, modern clean hotel, in room coffee and refrigerator."
United States
Thomas
4 days ago
$125 nightly
The price is $140
Jun 21 - Jun 22
Total with taxes and fees
Waterfront Hotel

Trickling Waters Retreat

Trickling Waters Retreat
3.0 star property
Marquette
9.8 out of 10, Exceptional, (300 reviews)
"Great helpful host. Beautifully mainted property inside and out. Quiet area with beautiful landscaping."
United States
Julie
21 days ago
$79 nightly
The price is $88
Jun 17 - Jun 18
Total with taxes and fees
Trickling Waters Retreat

Quality Inn & Suites Prairie Du Chien

Quality Inn & Suites Prairie Du Chien
2.5 star property
Southside
8.2 out of 10, Very Good, (450 reviews)
"Room was very clean. Pool was heated. Breakfast was good."
United States
Jennifer
13 days ago
$74 nightly
The price is $82
Jul 16 - Jul 17
Total with taxes and fees
Quality Inn & Suites Prairie Du Chien

Comfort Inn & Suites Marquette - Prairie du Chien

Comfort Inn & Suites Marquette - Prairie du Chien
2.5 star property
Marquette
9.0 out of 10, Wonderful, (989 reviews)
"Very comfortable room. Will definitely stay here again."
United States
Dianne
3 days ago
$82 nightly
The price is $92
Jul 16 - Jul 17
Total with taxes and fees
Comfort Inn & Suites Marquette - Prairie du Chien

Country Inn & Suites by Radisson, Prairie du Chien

Country Inn & Suites by Radisson, Prairie du Chien
3.0 star property
Prairie Du Chien
8.4 out of 10, Very Good, (1,011 reviews)
"I stayed at Choice Inn for my father s funeral."
United States
Julie
9 days ago
$97 nightly
The price is $108
Jul 5 - Jul 6
Total with taxes and fees
Country Inn & Suites by Radisson, Prairie du Chien

Northwood Inn Prairie Du Chien

Northwood Inn Prairie Du Chien
2.0 star property
Southside
8.4 out of 10, Very Good, (135 reviews)
"I love everything about staying at the Northwood inn."
United States
Brandon
May 4th, 2026
$77 nightly
The price is $85
Jun 30 - Jul 1
Total with taxes and fees
Northwood Inn Prairie Du Chien

Boarders Inn & Suites by Cobblestone Hotels – Waukon

Boarders Inn & Suites by Cobblestone Hotels – Waukon
3.5 star property
Waukon
8.0 out of 10, Very Good, (470 reviews)
"Room was nice. Parking was good. Just a place to stay."
United States
David
20 hours ago
$77 nightly
The price is $87
Jun 29 - Jun 30
Total with taxes and fees
Boarders Inn & Suites by Cobblestone Hotels – Waukon

Eagle View Motel & Retreat

Eagle View Motel & Retreat
2.5 star property
Guttenberg
9.4 out of 10, Exceptional, (182 reviews)
"Room was amazing. This hotel is definitely a hidden gem in Guttenburg."
United States
Michael
19 hours ago
$104 nightly
The price is $116
Jun 23 - Jun 24
Total with taxes and fees
Eagle View Motel & Retreat

Microtel Inn & Suites by Wyndham Prairie du Chien

Microtel Inn & Suites by Wyndham Prairie du Chien
2.5 star property
Southside
8.2 out of 10, Very Good, (610 reviews)
"The staff was extremely helpful and answered our questions honestly."
United States
Kathy
May 16th, 2026
$74 nightly
The price is $82
Jun 21 - Jun 22
Total with taxes and fees
Microtel Inn & Suites by Wyndham Prairie du Chien

Prairie Voyager

Prairie Voyager
2.5 star property
Southside
8.6 out of 10, Excellent, (135 reviews)
"The owner was very nice. Cost effective place to spend the night."
United States
Patricia
$65 nightly
The price is $72
Jul 9 - Jul 10
Total with taxes and fees
Prairie Voyager

Sleep Inn & Suites Lancaster-Platteville

Sleep Inn & Suites Lancaster-Platteville
2.5 star property
Lancaster
9.4 out of 10, Exceptional, (325 reviews)
"The bed was comfy, soft sheets. Best sleep I've experienced in a hotel."
United States
Tracy
5 days ago
$86 nightly
The price is $91
Jul 12 - Jul 13
Total with taxes and fees
Sleep Inn & Suites Lancaster-Platteville

AmericInn by Wyndham Boscobel

AmericInn by Wyndham Boscobel
3.0 star property
Boscobel
8.8 out of 10, Excellent, (498 reviews)
"Rooms were nice and clean and over hotel looked nice."
United States
Jordan
May 16th, 2026
$87 nightly
The price is $96
Jul 12 - Jul 13
Total with taxes and fees
AmericInn by Wyndham Boscobel

American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6

American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6
McGregor
10.0 out of 10, Exceptional, (17 reviews)
"We had a wonderful stay. Super clean, comfortable, got everything we need."
United States
Shengying
April 20th, 2026
$265 nightly
The price is $297
Jun 16 - Jun 17
Total with taxes and fees
American House 1854- Stagecoach Stop Suite, 2 Bedrooms, Kitchenette, Sleeps 6

Super 8 by Wyndham Dyersville near Field of Dreams

Super 8 by Wyndham Dyersville near Field of Dreams
2.5 star property
Dyersville
8.4 out of 10, Very Good, (735 reviews)
"The place was clean and beds were comfy!"
United States
Donna
18 hours ago
$85 nightly
The price is $95
Jun 21 - Jun 22
Total with taxes and fees
Super 8 by Wyndham Dyersville near Field of Dreams

American House 1854- Pocket City Penthouse, 2 Bedrooms, Full Kitchen & Dining

American House 1854- Pocket City Penthouse, 2 Bedrooms, Full Kitchen & Dining
McGregor
9.8 out of 10, Exceptional, (16 reviews)
"Really enjoyed our stay. Everything was perfect."
United States
Lisa
7 days ago
American House 1854- Pocket City Penthouse, 2 Bedrooms, Full Kitchen & Dining

Rivers Edge

Rivers Edge
2.5 star property
Cassville
10.0 out of 10, Exceptional, (4 reviews)
"It was so peaceful loved our stay."
United States
Jesellen
Rivers Edge

Comfort Inn Dyersville Near Field of Dreams

Comfort Inn Dyersville Near Field of Dreams
2.5 star property
Dyersville
8.8 out of 10, Excellent, (131 reviews)
"Beyond to make our stay superior. Would highly recommend. I was traveling with kids."
United States
Judith
May 15th, 2026
Comfort Inn Dyersville Near Field of Dreams

Motel 6 Prairie Du Chien, WI

Motel 6 Prairie Du Chien, WI
2.0 star property
Prairie Du Chien
6.6 out of 10, (343 reviews)
"The room was clean. The hotel is old. There are accommodation rooms."
United States
Barbara
Motel 6 Prairie Du Chien, WI
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Clayton Hotel Reviews

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Frequently asked questions

What is the best area to stay in Clayton?
The best area to stay in Clayton is along the Mississippi River, particularly near the town's main street, First Street.

This area is the heart of Clayton, providing direct access to the Mississippi River and its scenic views. First Street features several local shops and eateries, and it's where you'll find the public boat launch and picnic areas. The general layout is linear, following the riverbank, making it easy to navigate on foot. Couples will find this area appealing for its picturesque setting and opportunities for quiet strolls along the river.

For families, staying slightly off First Street but still within walking distance offers a good balance. You'll be close enough to enjoy the river activities and local amenities, but with a bit more space and less direct traffic.
When is the best time to go to Clayton?
The best time to go to Clayton, Iowa, is during the spring, summer, and fall months, typically from May through October.

These months offer the most pleasant weather for outdoor activities, with temperatures ranging from comfortable highs in the 60s and 70s Fahrenheit in spring and fall, to warmer averages in the 80s during the summer. This period is ideal for enjoying the Mississippi River, exploring local parks, and participating in community events.

For travelers who enjoy fishing, boating, or hiking, the summer months (June, July, August) are particularly good. The river is fully accessible, and many local businesses and attractions operate at their peak. Families often find the summer an excellent time to visit due to school holidays and a wider array of kid-friendly outdoor options.

Couples looking for a scenic and relaxing getaway might prefer the spring (May) or fall (September, October). During these times, the landscape is particularly beautiful with spring blossoms or autumn foliage, and the crowds are generally smaller than in mid-summer.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Clayton.
How can I save on a Clayton hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Clayton hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Clayton hotel?
Prices for hotels in Clayton often vary, but you can find a great deal from $72 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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