Title: Visit Clayton: 2026 Travel Guide for Clayton, Garnavillo | Expedia.com [Hotels in Clayton](https://expedia.com/Clayton-Hotels.d553248634983581969.Travel-Guide-Hotels)[Vacation Rentals in Clayton](https://expedia.com/Clayton-Vacation-Rentals.d553248634983581969.Travel-Guide-VacationRentals)[Car Rentals in Clayton](https://expedia.com/Car-Rentals-In-Clayton.d553248634983581969.Car-Rental-Guide)[Clayton Vacation Packages](https://expedia.com/Clayton.d553248634983581969.Destination-Travel-Guides) # Clayton, IA ## Travel Guide ## Visit Clayton - Clayton Hotel Deals - Vacation Rentals in Clayton ![Clayton Savings Bank - One Block To Might Mississippi River!](https://images.trvl-media.com/lodging/106000000/105770000/105766400/105766365/9c5b9190_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Savings Bank - One Block To Might Mississippi River! Garnavillo IA Stay at this vacation home in Garnavillo. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Glass Lake and Jays Lake are located ... [Get rates](https://expedia.com/Hotel-Search?startDate=4%2F10%2F2026&endDate=4%2F11%2F2026&selected=105766365&PinnedHotelID=105766365&HadPinnedHotel=true®ionId=553248634983581969) [](https://expedia.com/Hotel-Search?startDate=4%2F10%2F2026&endDate=4%2F11%2F2026&selected=105766365&PinnedHotelID=105766365&HadPinnedHotel=true®ionId=553248634983581969) ![Quality Inn & Suites Prairie Du Chien](https://images.trvl-media.com/lodging/1000000/10000/2100/2074/9f106ee3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Quality Inn & Suites Prairie Du Chien 37268 US Highway 18 Prairie Du Chien WI $57 nightly $63 total Apr 4 - Apr 5 Total with taxes and fees Book a stay at this business-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ... 8.2/10 Very Good! (432 reviews) My stay was excellent. Staff especially were the best! Unfortunately when we pulled out the sofa bed the sheets were dirty, but I'm guessing whoover slept in it probably put the bed back to couch position so cleaning missed it? At any rate the front desk was quick to remedy the situation. Definitely ... Reviewed on Mar 26, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F4%2F2026&endDate=4%2F5%2F2026&selected=2074&PinnedHotelID=2074&HadPinnedHotel=true®ionId=553248634983581969) ![Country Inn & Suites by Radisson, Prairie du Chien](https://images.trvl-media.com/lodging/1000000/980000/970800/970791/2a563b2e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Country Inn & Suites by Radisson, Prairie du Chien 1801 Cabela's Lane Prairie Du Chien WI $90 nightly $100 total Apr 19 - Apr 20 Total with taxes and fees Book a stay at this family-friendly hotel in Prairie Du Chien. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our ... 8.4/10 Very Good! (1,001 reviews) The pool was great. My 5 year old loved it. Reviewed on Mar 15, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F19%2F2026&endDate=4%2F20%2F2026&selected=970791&PinnedHotelID=970791&HadPinnedHotel=true®ionId=553248634983581969) [See all 104 properties in Clayton](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=3%2F28%2F2026&endDate=3%2F29%2F2026®ionId=553248634983581969) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Clayton Savings Bank - One Block To Might Mississippi River!](https://images.trvl-media.com/lodging/106000000/105770000/105766400/105766365/9c5b9190_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Savings Bank - One Block To Might Mississippi River! Garnavillo IA Stay at this vacation home in Garnavillo. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Glass Lake and Jays Lake are located ... [](https://expedia.com/Garnavillo-Hotels-Clayton-Savings-Bank-One-Block-To-Might-Mississippi-River.h105766365.Hotel-Information) ![Mr. Rogers River View](https://images.trvl-media.com/lodging/75000000/74900000/74896100/74896070/w905h683x60y0-d140bc38_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Mr. Rogers River View Guttenberg IA Stay at this apartment in Guttenberg. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions River Side Park and Guttenberg Public Library ... 9.6/10 Exceptional! (39 reviews) We enjoyed relaxing in the living area. We ate at the Lighthouse in Clayton. We visited the coffee shop, brewery and winery. This place has a great view. Our only complaint was the bed. Reviewed on Oct 24, 2025 [](https://expedia.com/Guttenberg-Hotels-Mr-Rogers-River-View.h74896070.Hotel-Information) ![Paint Creek Lodge ... 5 Bedroom A-Frame Log Cabin W/Hot Tub & Swimming Pond](https://images.trvl-media.com/lodging/113000000/112180000/112179000/112178933/8dfedae1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Paint Creek Lodge ... 5 Bedroom A-Frame Log Cabin W/Hot Tub & Swimming Pond Harpers Ferry IA Stay at this cabin in Harpers Ferry. Enjoy private pools, laundry facilities, and patios. Popular attractions Noble's Island and Waukon Junction Wildlife Area ... 6.4/10 (6 reviews) Todo muy limpio y Reviewed on Feb 21, 2026 [](https://expedia.com/Harpers-Ferry-Hotels-5-Bedroom-A-Frame-Log-Cabin-WHot-Tub-Swimming-Pond.h112178933.Hotel-Information) [See all properties in Clayton](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248634983581969&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Clayton hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=2026-03-27&endDate=2026-03-28)[Mar 27 - Mar 28](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=2026-03-27&endDate=2026-03-28) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=2026-03-28&endDate=2026-03-29)[Mar 28 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=2026-03-28&endDate=2026-03-29) [This weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026)[Mar 27 - Mar 29](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248634983581969&startDate=3%2F27%2F2026&endDate=3%2F29%2F2026) - Cities near Clayton - Places of interest [Bagley](https://expedia.com/Bagley.dx6360112)[Garnavillo](https://expedia.com/Garnavillo.dx3000436955) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Wisconsin River ](https://expedia.com/Wisconsin-River-Wisconsin.d553248621532659179.Vacation-Attraction) - [Wyalusing State Park ](https://expedia.com/Wyalusing-State-Park-Bagley.d553248621532649493.Vacation-Attraction) - [Yellow River State Forest ](https://expedia.com/Yellow-River-State-Forest-Harpers-Ferry.d553248621558786527.Vacation-Attraction) - [Effigy Mounds National Monument ](https://expedia.com/Effigy-Mounds-National-Monument-Iowa.d6106032.Vacation-Attraction) - [Pikes Peak State Park ](https://expedia.com/Pikes-Peak-State-Park-McGregor.d553248621532649494.Vacation-Attraction) - [Casino Queen ](https://expedia.com/Casino-Queen-Marquette.d553248621532649495.Vacation-Attraction) - [Spook Cave ](https://expedia.com/Spook-Cave-McGregor.d553248621532649492.Vacation-Attraction) - [St. Feriole Island Park ](https://expedia.com/St-Feriole-Island-Park-Prairie-Du-Chien.d553248621557045896.Vacation-Attraction) - [Villa Louis ](https://expedia.com/Villa-Louis-Prairie-Du-Chien.d553248621532649497.Vacation-Attraction) - [Charles Wacouta Aquatic Park ](https://expedia.com/Charles-Wacouta-Aquatic-Park-Prairie-Du-Chien.d553248621557045898.Vacation-Attraction) - [Nelson Dewey State Park ](https://expedia.com/Nelson-Dewey-State-Park-Cassville.d553248621532649420.Vacation-Attraction) - [Fort Fun Park ](https://expedia.com/Fort-Fun-Park-Prairie-Du-Chien.d553248621557045899.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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