Luxury Hotels in Mississippi from $59

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Pick from 121 Mississippi Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Beau Rivage

4.0 star property
Downtown Biloxi
  • Near the beach
  • 10 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
9.2 out of 10, Wonderful, (1408)
Seaside indulgence defines this upscale retreat where 14 spa treatment rooms offer aromatherapy, reflexology, and couples massages. Deep soaking tubs and pillowtop beds complement the 7 bars, outdoor pool, and vibrant casino featuring 1000 slot machines.
$131 nightly
The price is $146
Nov 10 - Nov 11
Total with taxes and fees
Beau Rivage

Margaritaville Resort Biloxi

3.5 star property
Biloxi
  • 3 restaurants
  • 24-hour gym
  • Poolside bar
8.6 out of 10, Excellent, (5475)
Vacation elegance flows through this beachfront haven featuring 3 restaurants, 2 stylish bars, and a spectacular water park with swim-up service. Pillowtop beds and ocean views complete the experience in spacious rooms where coastal luxury meets vibrant entertainment options.
$110 nightly
The price is $121
Dec 1 - Dec 2
Total with taxes and fees
Margaritaville Resort Biloxi

White House Hotel

3.0 star property
Biloxi
  • Concierge services
8.8 out of 10, Excellent, (1034)
Seaside elegance defines this tranquil Biloxi hotel where attentive staff cater to every need. Savor delicious cuisine at Cora's restaurant, unwind in the peaceful pool area, or admire breathtaking ocean views from the rooftop terrace. Premium bedding ensures blissful nights after beach adventures.
$118 nightly
The price is $133
Dec 7 - Dec 8
Total with taxes and fees
White House Hotel

The Guest House Historic Mansion

3.5 star property
Natchez
  • Concierge services
9.2 out of 10, Wonderful, (819)
Savor luxury moments in this stately 16-room bed & breakfast where historic charm meets modern comfort. Guests relax on rocking chair-lined porches, indulge in complimentary gourmet breakfasts, and enjoy exceptional dining at the on-site restaurant, all within walking distance of Natchez landmarks.
$124 nightly
The price is $139
Nov 12 - Nov 13
Total with taxes and fees
The Guest House Historic Mansion

IP Casino Resort Spa - Biloxi

4.0 star property
Biloxi
  • 7 restaurants
  • Full-service spa
  • Poolside bar
  • Concierge services
8.6 out of 10, Excellent, (5138)
Pampered indulgence awaits at this upscale waterfront retreat. Guests rave about the 19-room spa featuring hot stone massages, sauna, and reflexology. After enjoying exceptional dining across multiple restaurants, visitors can try their luck at the casino or unwind by the seasonal outdoor pool.
$88 nightly
The price is $99
Nov 30 - Dec 1
Total with taxes and fees
IP Casino Resort Spa - Biloxi

Duff Green Mansion

4.0 star property
Vicksburg
  • Outdoor pool
  • Concierge services
9.4 out of 10, Exceptional, (924)
Sumptuous accommodations await at this Victorian bed & breakfast where 8 individually decorated rooms feature private pools and premium bedding. Guests savor complimentary breakfast each morning before lounging by the outdoor pool or strolling through manicured gardens.
$144 nightly
The price is $158
Nov 30 - Dec 1
Total with taxes and fees
Duff Green Mansion

Gold Strike Casino Resort

3.5 star property
Robinsonville
  • 5 restaurants
  • Full-service spa
  • Concierge services
8.2 out of 10, Very Good, (1001)
Stepping into this entertainment district haven reveals a world of pampering possibilities. Guests relish deep-tissue, sports, and Thai massages at the full-service spa while enjoying premier dining across 5 restaurants. Casino thrills complement luxury amenities in this sophisticated retreat.
$149 nightly
The price is $163
Nov 9 - Nov 10
Total with taxes and fees
Gold Strike Casino Resort

Golden Nugget Biloxi

4.0 star property
Downtown Biloxi
  • Near private beach
  • Ocean-view dining
  • Full-service spa
  • Poolside bar
  • Concierge services
8.0 out of 10, Very Good, (2692)
Sophisticated relaxation awaits at this coastal retreat featuring 2 outdoor pools with a swim-up bar. The 9-room spa offers hot stone massages and aromatherapy while 4 restaurants serve ocean-view dining. Gaming enthusiasts appreciate the casino's 49 tables and 1159 slot machines.
$78 nightly
The price is $85
Dec 1 - Dec 2
Total with taxes and fees
Golden Nugget Biloxi

Best Western Airport Inn

2.5 star property
Pearl
  • Outdoor pool
7.8 out of 10, Good, (1001)
Sophisticated travelers appreciate the meticulous attention to detail throughout this Pearl retreat. Spacious rooms feature premium channels and plush beds, while the sparkling outdoor pool offers refreshing relaxation after exploring nearby attractions, including Trustmark Park just 1.3 mi away.
$66 nightly
The price is $74
Nov 16 - Nov 17
Total with taxes and fees
Best Western Airport Inn

Quality Inn Robinsonville

2.5 star property
Robinsonville
  • 24-hour gym
7.8 out of 10, Good, (729)
Personalized luxury awaits at this quiet retreat near Tunica's casinos. Morning begins with a complimentary gourmet breakfast before guests explore nearby entertainment. Spotlessly clean accommodations and attentive staff create a premium experience for travelers and their pets.
$54 nightly
The price is $59
Nov 16 - Nov 17
Total with taxes and fees
Quality Inn Robinsonville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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