Luxury Hotels in Missouri from $121
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Pick from 414 Missouri Luxury Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
9.0 out of 10, Wonderful, (1012)
$222 nightly
The price is $262
Jul 27 - Jul 28
Total includes taxes and fees

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1003)
$183 nightly
The price is $214
Aug 10 - Aug 11
Total includes taxes and fees

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (538)
$579 nightly
The price is $674
Jul 20 - Jul 21
Total includes taxes and fees

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1002)
$495 nightly
The price is $579
Jul 14 - Jul 15
Total includes taxes and fees

Moberly Inn and Suites
Moberly Inn and Suites
5.0 out of 10, (172)

Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
8.8 out of 10, Excellent, (2929)
$104 nightly
The price is $121
Jul 20 - Jul 21
Total includes taxes and fees

The Westin St. Louis
The Westin St. Louis
8.6 out of 10, Excellent, (1004)
$127 nightly
The price is $148
Aug 3 - Aug 4
Total includes taxes and fees

Cliffs Resort Table Rock Lake
Cliffs Resort Table Rock Lake
9.2 out of 10, Wonderful, (967)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent reviews of Missouri hotels
Recent reviews of Missouri hotels

Clayton Plaza Hotel & Extended Stay
5/5 Excellent
"Great hotel, I loved the room had no carpet, a beautiful clean floor. Excellent breakfast."
A verified traveler from Smyrna stayed at Clayton Plaza Hotel & Extended Stay
Posted 6 hours ago
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