Title: 20 Best B&B in Florence, SC - Bed and Breakfast from $132 | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide)[Florence Vacation Packages](https://expedia.com/Florence.d1221.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-13&endDate=2026-02-15&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-02-20&endDate=2026-02-22&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=1221&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florence bed & breakfast ![Front of property](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/aa63167f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/d1fd3c46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/b50f6cbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/27000000/26740000/26733800/26733717/743f97fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1912 Bed and Breakfast [](https://www.expedia.com/Sumter-Hotels-1912-Bed-And-Breakfast.h26733717.Hotel-Information) Sumter 10/10 Exceptional (287 reviews) "Comfortable beautiful bed and breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana $132 nightly $132 total Feb 9 - Feb 10 Total with taxes and fees [](https://www.expedia.com/Sumter-Hotels-1912-Bed-And-Breakfast.h26733717.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=1221&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Bed-And-Breakfast.d1221-aaBedAndBreakfast.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FFlorence-Bed-And-Breakfast.d1221-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Florence Hotel Reviews ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "The room was clean. The bed was comfortable. We had great water pressure. The shower was very clean, no mildew! Plenty of immediate hot water. We had enough towels. The fridge was clean. Hand/body lotion would have been a nice amenity" [](https://expedia.com/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "Our room was fine and the staff was helpful." [](https://expedia.com/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "Everything was as expected. " [](https://expedia.com/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Home2 Suites by Hilton Florence, SC](https://images.trvl-media.com/lodging/8000000/7280000/7271300/7271220/25ce2409_y.jpg) ### Home2 Suites by Hilton Florence, SC 10/10 Excellent "Great room" [](https://expedia.com/Florence-Hotels-Home2-Suites-By-Hilton-Florence.h7271220.Hotel-Information) ![Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG](https://images.trvl-media.com/lodging/1000000/970000/970000/969975/9fdaeb31_y.jpg) ### Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG 10/10 Excellent "yes" [](https://expedia.com/Florence-Hotels-Holiday-Inn-Express-Hotel-Suites-Florence-I-95-At-Hwy-327.h969975.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "all of the above" [](https://expedia.com/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Great room and reasonable price " [](https://expedia.com/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "Room was as clean as expected was satisfied " [](https://expedia.com/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5_y.jpg) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG 10/10 Excellent "Clean room great Breakfast and convince parking " [](https://expedia.com/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ## Find out more about Florence ## Florence B&B information | Number of reviews | 287 | | ----------------- | ----- | | Accommodation | 3 B&B | | Lowest Price | $132 | | Highest Price | $132 | ## Frequently asked questions ### What is the nightly rate for a Bed & Breakfast in Florence? ### What is the difference between a Florence B&B and a hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - [Flights from New York (JFK) to Florence (FLO) ](https://www.expedia.com/lp/flights/jfk/flo/new-york-to-florence) - [Flights from Charlotte (CLT) to Florence (FLO) ](https://www.expedia.com/lp/flights/clt/flo/charlotte-to-florence) - 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[Flights from Missoula (MSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO) ](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO) ](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from New Haven (HVN) to Florence (FLO) ](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO) ](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Harrisburg (MDT) to Florence (FLO) ](https://www.expedia.com/lp/flights/mdt/flo/harrisburg-to-florence) - [Flights from Washington (IAD) to Florence (FLO) ](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Boise (BOI) to Florence (FLO) ](https://www.expedia.com/lp/flights/boi/flo/boise-to-florence) - [Flights from Allentown (ABE) to Florence (FLO) ](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO) ](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Montgomery (MGM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mgm/flo/montgomery-to-florence) - [Flights from Eugene (EUG) to Florence (FLO) ](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Fayetteville (FAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/fay/flo/fayetteville-to-florence) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - [Hertz Rental Cars in Florence Regional ](https://www.expedia.com/Hertz-Car-Rentals-In-Florence-Regional.d6027805-c40.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Florence Regional ](https://www.expedia.com/Avis-Car-Rentals-In-Florence-Regional.d6027805-c41.Car-Rental-Guide-Suppliers) - [Car rental Florence Airport (FLO) ](https://www.expedia.com/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Budget Rental Cars in Florence Regional ](https://www.expedia.com/Budget-Car-Rentals-In-Florence-Regional.d6027805-c39.Car-Rental-Guide-Suppliers)