Top 10 Hotels in Florence, MO (from $62) 2026 - Competitive Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Florence hotels

1. Camden on the Lake Resort & Spa

Lake Ozark

Justin

$175 nightly

Aug 20 - Aug 21

Total with taxes and fees

2. Alhonna Resort LLC

Lake Ozark

Ryan N

$116 nightly

Aug 11 - Aug 12

Total with taxes and fees

3. Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Boonville

Donna

$86 nightly

Jul 30 - Jul 31

Total with taxes and fees

4. Days Inn by Wyndham Boonville

Boonville

Angie

$42 nightly

Aug 2 - Aug 3

Total with taxes and fees

5. Super 8 by Wyndham Lake of the Ozarks

Eldon

David

$76 nightly

Aug 9 - Aug 10

Total with taxes and fees

6. Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

Sedalia Downtown Historic District

Cynthia

$116 nightly

Aug 9 - Aug 10

Total with taxes and fees

7. Hotel Frederick

Boonville

Francis

$137 nightly

Jul 30 - Jul 31

Total with taxes and fees

8. The Lake House Inn

Laurie

Erik

$120 nightly

Jul 30 - Jul 31

Total with taxes and fees

9. Comfort Inn Sedalia Station

Sedalia

Tammy

$116 nightly

Aug 29 - Aug 30

Total with taxes and fees

10. Best Western State Fair Inn

Sedalia

Kyle

$113 nightly

Aug 5 - Aug 6

Total with taxes and fees

11. Coconuts RV Resort

Gravois Mills

Timothy

$1,395 nightly

Aug 3 - Aug 4

Total with taxes and fees

12. Econo Lodge Truman Inn

Sedalia

Wendy

$78 nightly

Aug 2 - Aug 3

Total with taxes and fees

13. Holiday Inn Express & Suites Sedalia by IHG

Sedalia

Michael

$119 nightly

Aug 28 - Aug 29

Total with taxes and fees

14. Hawthorne Inn

Versailles

Zebadiah

$120 nightly

Aug 3 - Aug 4

Total with taxes and fees

15. Hampton Inn Sedalia

Sedalia

Ronald

$119 nightly

Aug 24 - Aug 25

Total with taxes and fees

16. Holiday Inn Express Boonville by IHG

Boonville

Deborah

$136 nightly

Aug 23 - Aug 24

Total with taxes and fees

Desk, blackout drapes, iron/ironing board, WiFi (free)

17. Motel 6 Sedalia, MO

Sedalia

Gary

$56 nightly

Aug 25 - Aug 26

Total with taxes and fees

18. Quality Inn & Suites Boonville - Columbia

Boonville

jan

$116 nightly

Aug 13 - Aug 14

Total with taxes and fees

19. Eldon Inn

Eldon

Andrea

$80 nightly

Jul 30 - Jul 31

Total with taxes and fees

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Where to stay near Florence

Florence offers a charming blend of outdoor adventures and scenic beauty, perfect for romantic getaways or family trips. Explore the surrounding neighborhoods to enjoy a family-friendly atmosphere and create unforgettable memories amidst nature’s splendor. Discover the tranquility that awaits in this delightful city.

A large, classical building with columns and a statue in front.

Sedalia

Discover Sedalia, a welcoming destination perfectly suited for travelers seeking a blend of outdoor adventure and local charm. With attractions like the Missouri State Fairgrounds, Katy Trail State Park, and Bothwell Lodge State Historic Site, visitors can enjoy a variety of recreational experiences year-round. Located about 20 miles by car from Florence, Sedalia provides easy access to serene landscapes and vibrant community events, making it a smart hotel booking choice for your next getaway.

See properties

Otterville

Experience the charm of Otterville, an excellent hub for family and nature enthusiasts looking to explore Missouri's beautiful landscapes. With attractions like the Missouri State Fairgrounds, Katy Trail State Park, and the historic Ravenswood, visitors can enjoy a blend of outdoor activities and cultural experiences. Located about 8 miles from Florence, Otterville offers a budget-friendly option for travelers seeking a memorable getaway. A stay here is a smart choice for those wanting to immerse themselves in scenic beauty and local history.

See properties

Syracuse

If you are a family or business traveler, look no further than Syracuse, Missouri, which features a blend of outdoor adventures and cultural experiences. Enjoy the beauty of the Ozark Caverns and explore the trails at Katy Trail State Park, perfect for a day of fun. With attractions like Ravenswood and an urban park nearby, there’s something for everyone. Located about 8 miles from Florence, Syracuse is an excellent choice for your stay, offering a welcoming and accessible experience.

See properties

Smithton

Ideal for families and outdoor enthusiasts, Smithton is a delightful gateway to a wealth of experiences. Visitors can explore the scenic Katy Trail State Park, immerse themselves in the local history at the Katy Depot, or enjoy the lively atmosphere of the Missouri State Fairgrounds. Located about 9 miles from Florence, Smithton offers easy access to these attractions, making it a smart choice for your next getaway. With its charming community and variety of activities, your stay in Smithton promises to be memorable.

See properties

A calm lake with reflections of colorful lights, docked boats, and a forested hillside in the background.

Stover

Travelers seeking a charming getaway will find Stover, Missouri, to be the ideal base for their vacation, featuring a blend of family-friendly activities, scenic nature spots, and budget-friendly options. With attractions like Jacob's Cave, Proctor Towersite State Wildlife Area, and Carpenter Memorial Conservation Area nearby, visitors can enjoy outdoor adventures and beautiful landscapes year-round. Located about 10 miles from Florence, Stover is a smart choice for those looking to explore the area while enjoying a relaxing stay.

See properties

Stay near popular attractions around Florence

Nestled in scenic surroundings, Florence is perfect for outdoor enthusiasts and romantic getaways. Explore the local fairgrounds, enjoy the natural beauty of nearby state parks, and delve into history at the railway museum. This charming destination offers a delightful blend of adventure, culture, and family fun.

A large Ferris wheel at a fair with people around it.

Missouri State Fairgrounds

8.8/10 (226 reviews)

Experience the best of family-friendly fun at the Missouri State Fairgrounds, located about 17 miles from Florence. This vibrant venue offers outdoor activities and seasonal events that create lasting memories. Staying nearby makes it easy to enjoy the lively atmosphere and various attractions throughout the year.

See properties

Top Florence Hotel Reviews

Comfort Inn Sedalia Station

10/10 Excellent

"This was a great hotel, we spent a lot of time in the lobby area with our friends because it had a very inviting atmosphere.. The room was very clean and comfortable!"

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

10/10 Excellent

"It keeps its old charm that takes you back to yesteryear. It's clean friendly and downtown in a walkable shopping area. Being old the rooms aren't overly large but they are comfortable. Breakfast had fresh cooked eggs."

Florence Cabin w/ On-Site Creek!

10/10 Excellent

"We loved how secluded it was from everything. The house was very clean and the deck was nice to set out on and grill. We cooled of in the creek with our chairs and it was the perfect height and flowing. They had everything that we needed to have a fire at the end of the night. They left us delicious cookies and was very quick to reply to any of our questions. Would definitely stay again!"

More cheap stays in Florence

American Inn Sedalia

1217 S Limit Ave Sedalia MO

$55 nightly

$63 total

Aug 24 - Aug 25

Total with taxes and fees

5.4/10 (248 reviews)

Hotels in Florence with star-rating

Frequently asked questions

What is the best area to stay in Florence?

The best area to stay in Florence, Missouri, is the historic downtown area, specifically around Main Street.

This area is the heart of Florence, offering a collection of well-preserved 19th-century buildings that house local shops, eateries, and a few bed-and-breakfasts. Main Street is easily walkable, and you'll find the town's small park and the Florence Historical Society Museum within a few blocks.

Travelers looking for a quiet retreat will appreciate the pace of downtown Florence.

When is the best time to go to Florence?

The best time to visit Florence, Missouri, is during the spring (April to May) and fall (September to October) months.

These seasons offer pleasant weather conditions, with comfortable temperatures that are ideal for outdoor activities and exploring the natural beauty of the region. Spring brings blooming wildflowers and lush greenery, while the fall foliage provides a colorful backdrop. These periods also generally see fewer crowds compared to the peak summer months.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Florence.

How much is the nightly rate at a Florence hotel?

Prices for hotels in Florence often vary, but you can find a great deal from $62 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Things to do in Missouri

Find hotels in Florence, MO from $62

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Florence

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Florence hotels

1. Camden on the Lake Resort & Spa

2. Alhonna Resort LLC

3. Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

4. Days Inn by Wyndham Boonville

5. Super 8 by Wyndham Lake of the Ozarks

6. Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel

7. Hotel Frederick

8. The Lake House Inn

9. Comfort Inn Sedalia Station

10. Best Western State Fair Inn

11. Coconuts RV Resort

12. Econo Lodge Truman Inn

13. Holiday Inn Express & Suites Sedalia by IHG

14. Hawthorne Inn

15. Hampton Inn Sedalia

16. Holiday Inn Express Boonville by IHG

17. Motel 6 Sedalia, MO

18. Quality Inn & Suites Boonville - Columbia

19. Eldon Inn

Where to stay near Florence

Sedalia

Otterville

Syracuse

Smithton

Stover

Stay near popular attractions around Florence

Missouri State Fairgrounds

Top Florence Hotel Reviews

Comfort Inn Sedalia Station

More cheap stays in Florence

American Inn Sedalia

Hotels in Florence with star-rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app