Midtown Vacations from $143

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Your Midtown Vacation

Lose yourself in the wonder of this commercial neighborhood with a Midtown vacation package. From its nightlife and bars and pubs to its dining, there's something for every type of traveler. Want to see the sights during your trip to Midtown? Be sure to check out nearby attractions like Toyota Center, Minute Maid Park and Houston Zoo. Don't just think about it — turn it into a reality! Book your ideal Midtown vacation with Expedia and experience travel your way.

The Latest Midtown Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Stay Inn & Suites
The Lancaster Hotel
Landing Apartments Houston Southbelt
Garden Inn Express
La Quinta Inn & Suites by Wyndham Houston East at Normandy

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown

Midtown Hotel Deals

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd, Houston, TX
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $144 total per night from Aug 31 to Sep 1
$144 total
Aug 31 - Sep 1
Total with taxes and fees
8/10 Very Good! (2,422 reviews)
"The staff was amazing! They made it worth while. Thank you Double tree staff."

Reviewed on Aug 22, 2025

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street, Houston, TX
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $123 total per night from Aug 26 to Aug 27
$123 total
Aug 26 - Aug 27
Total with taxes and fees
8.4/10 Very Good! (3,621 reviews)
"Very nice place to stay and a great staff!"

Reviewed on Aug 21, 2025

Club Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $104 total per night from Sep 7 to Sep 8
$104 total
Sep 7 - Sep 8
Total with taxes and fees
8.2/10 Very Good! (1,531 reviews)
Enjoyed our stay b
"Nice accommodations, nice pool. Free or discounted parking would have made it even better."

Reviewed on Aug 23, 2025

Hilton Houston Plaza/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Midtown

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.