Midtown Vacations from $259
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Your Midtown Vacation
Lose yourself in the wonder of this commercial neighborhood with a Midtown vacation package. From its nightlife and bars and pubs to its dining, there's something for every type of traveler. Want to see the sights during your trip to Midtown? Be sure to check out nearby attractions like Toyota Center, Minute Maid Park and Houston Zoo. Don't just think about it — turn it into a reality! Book your ideal Midtown vacation with Expedia and experience travel your way.
The Latest Midtown Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Experience a First Class Stay - 2 BDRM
Save 100% on your flight
Price was $692, price is now $441 per person
$441
per person
Aug 13 - Aug 16
found 8 hours ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8/10 Very Good! (5 reviews)
This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well.
Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN.
Reviewed on Mar 11, 2022
Where to stay in Midtown
Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Downtown Houston
3 out of top 10 points of interest in this area
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Midtown Hotel Deals
Grand Tuscany Hotel
12801 Northwest Fwy Houston TX
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from Jul 19 to Jul 20
$122 total
Jul 19 - Jul 20
Total with taxes and fees
8/10 Very Good! (169 reviews)
"Beautiful hotel. Good amenities. If breakfast was complimentary this would be a 5-star easily! Will definitely book again."
Reviewed on Jul 14, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $118 total per night from Jul 24 to Jul 25
$118 total
Jul 24 - Jul 25
Total with taxes and fees
8.4/10 Very Good! (2,038 reviews)
"I usually don’t leave reviews, but I had to leave one. I just went to Houston for the Dreamcon convention and the next time I come back for next year, I will be also staying at this hotel! The staff are extremely nice and friendly. The rooms are spacious, and the beds are very comfortable! There’s ..."
Reviewed on Jul 14, 2026
Club Quarters Hotel Downtown, Houston
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $109 total per night from Aug 14 to Aug 15
$109 total
Aug 14 - Aug 15
Total with taxes and fees
8.6/10 Excellent! (4,328 reviews)
"Our room’s walls could have been wiped a bit better, there were odd beverage splatters, and there were used coffee pods in the nespresso drawer, but honestly besides those super minor things, we had an amazing experience. I think it would have been amazing if there was free onsite parking for customers ..."
Reviewed on Jul 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Midtown attractions
Things to do
Houston: Space Center Houston Admission Ticket
$30
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
$109
per adult
92% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
Explore a world of travel with Expedia
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- South Central Houston Vacations
- Houston Zoo
- Gerald D. Hines Waterwall Park
- Holocaust Museum Houston
- Discovery Green
- Shops at Houston Center
- Houston Museum of Fine Arts
- Sylvan Beach Park
- Color Factory Houston
- Rice University
- Buffalo Soldiers National Museum
- Buffalo Bayou Park
- Hobby Center for the Performing Arts
- Cullen Sculpture Garden
- Alley Theater
- Houston City Hall
- Houston Sports Museum
- Six Flags Hurricane Harbor
- Kemah Boardwalk
- Theatre Under The Stars
- Toyota Center
- Nrg Stadium
- Rothko Chapel
- Memorial Vacations
- Shell Energy Stadium
- The Chapel of St. Basil
- Daikin Park
- Wortham Center
- Greenway Plaza
- University of Houston - Downtown
- Bayou Place
- North Houston Vacations
- River Oaks Country Club
- Traders Village
- Health Museum
- Downtown Aquarium
- Saint Arnold Brewery
- Downtown Houston Vacations
- Kinder Lake
- Highland Village
- Giant Beatles Statues
- Harris Health System - Ben Taub General Hospital
- House of Blues Houston
- Houston Vacations
- Allen's Landing Park
- Bayou Bend Collection and Gardens
- Houston Natural Science Museum
- Houston JPMorgan Chase Tower
- Visit Houston
- Cy Twombly Gallery
- Hermann Park
- Houston Police Officer Memorial
- Space Center Houston
- Jesse H. Jones Hall
- Main Street Theater - Rice Village
- Continental Club
- Christ Church Cathedral
- Menil Collection
- Houston Arboretum and Nature Center
- George R. Brown Convention Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.