Northeast Missouri Vacations from $271
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Your Northeast Missouri Vacation
When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Center and Busch Stadium. St. Charles is another top city that draws travelers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.
The Latest Northeast Missouri vacation packages
Price found within the past 48 hours. Click for updated prices.
The Cheshire
Save 100% on your flight
Price was $561, price is now $332 per person
$332
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,001 reviews)
Pretty location. Direct access to the park. Cycled everywhere. Private secure car park.
Reviewed on Jul 15, 2026
Residence Inn by Marriott St Louis Downtown
Midtown
Price was $896, price is now $592 per person
$592
per person
Sep 21 - Sep 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to St. Louis (STL)
7.8/10 Good! (1,001 reviews)
First room we were assigned smelled like thick smoke. The second room’s toilet didn’t work. The staff was not helpful and very slow to respond.
Reviewed on Jul 15, 2026
The Knight Center at Washington University
Save 100% on your flight
Price was $442, price is now $295 per person
$295
per person
Sep 17 - Sep 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.4/10 Exceptional! (592 reviews)
It has ice machine and filtered water, microwave too !
Reviewed on Jul 16, 2026
Don't see what you're looking for?
See all available trips from Columbus to Northeast Missouri
View all tripsWhere to stay in Northeast Missouri
Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
Clayton
1 out of top 10 points of interest in this area
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
Stay near popular Northeast Missouri attractions
What to do in Northeast Missouri
Tom's Town Distillery Tour and Tasting
$27
per adult
100% of travellers recommend
Northeast Missouri Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Aug 9 to Aug 10
$110 total
Aug 9 - Aug 10
Total with taxes and fees
9/10 Wonderful! (3,251 reviews)
"Clean hotel, helpful staff, covered parking. Good breakfast great variety. Walking distance to Metrolink station."
Reviewed on Jul 16, 2026
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $162 total per night from Jul 27 to Jul 28
$162 total
Jul 27 - Jul 28
Total with taxes and fees
8.6/10 Excellent! (2,226 reviews)
"Na"
Reviewed on Jul 16, 2026
Forest Park Hotel by MDR
5915 Wilson Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Aug 16 to Aug 17
$115 total
Aug 16 - Aug 17
Total with taxes and fees
7.4/10 Good! (1,628 reviews)
"I arrived at this property and it was horrible on the outside. I checked in and went to my room and found that the TV didn't work, the bed were bad, carpet smell and stains and bathroom was terrible. Went back to get a refund and did not get it yet. This was June 26 2026 and I am still fighting for ..."
Reviewed on Jul 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Northeast Missouri Vacation Packages
Northeast Missouri Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
