Northeast Missouri Vacations from $258
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Your Northeast Missouri Vacation
When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Center and Busch Stadium. St. Charles is another top city that draws travelers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.
The Latest Northeast Missouri vacation packages
White House at Grand Central
Reviewed on Nov 11, 2025
Hilton Garden Inn Chesterfield
Reviewed on Dec 22, 2025
The Knight Center at Washington University
Reviewed on Jan 12, 2026
Marriott St. Louis West
Reviewed on Jan 11, 2026
Where to stay in Northeast Missouri
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Discover the most popular places to visit in Northeast Missouri
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
What to do in Northeast Missouri
Tom's Town Distillery Tour and Tasting
Northeast Missouri Hotel Deals
Clayton Plaza Hotel & Extended Stay
Overall great experience and amazing facility the pillows could use a upgrade but overall very happy.
Reviewed on Jan 12, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Wonderful stay
Reviewed on Jan 8, 2026
21C Museum Hotel St Louis
Good vibe
Reviewed on Jan 7, 2026
Find the Best Northeast Missouri Vacation Packages
Northeast Missouri Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
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