Title: Ethel Vacation Packages 2026 from $483 | Expedia.com [Ethel Travel Guide](https://expedia.com/Ethel.dx102383)[Hotels in Ethel](https://expedia.com/Ethel-Hotels.d102383.Travel-Guide-Hotels)[Vacation Rentals in Ethel](https://expedia.com/Ethel-Vacation-Rentals.d102383.Travel-Guide-VacationRentals)[Flights to Ethel](https://expedia.com/Cheap-Flights-To-Ethel.d102383.Travel-Guide-Flights)[Car Rentals in Ethel](https://expedia.com/Car-Rentals-In-Ethel.d102383.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Ethel Vacations from $483 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## The Latest Ethel vacation packages Price found within the past 48 hours. Click for updated prices. ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Wildwood Hotel $483 per person May 11 - May 15 found 1 day ago Roundtrip flight included Baltimore (BWI) to St. Louis (STL) 9.2/10 Wonderful! (1,600 reviews) Great place to stay! We arrived later at night around 11pm and the front desk gal working at that time was wonderful. Nice, quiet, clean and in a very nice area. Reviewed on Feb 27, 2026 ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton Grand Center $567 per person May 11 - May 15 found 1 day ago Roundtrip flight included Baltimore (BWI) to St. Louis (STL) 8.8/10 Excellent! (1,022 reviews) Great customer service. The locals there are friendly as well as the staff members Reviewed on Feb 23, 2026 ![Ameristar Casino Hotel Kansas City](https://images.trvl-media.com/lodging/1000000/50000/41600/41546/ad53926e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ameristar Casino Hotel Kansas City Birmingham Bottoms $499 per person Apr 17 - Apr 19 found 10 hours ago Roundtrip flight included Baltimore (BWI) to Kansas City (MCI) 8.6/10 Excellent! (1,005 reviews) Everything was top notch Reviewed on Feb 27, 2026 ![DoubleTree by Hilton St. Louis Forest Park](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/3f93ad2e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton St. Louis Forest Park Central West End $633 per person May 11 - May 15 found 1 day ago Roundtrip flight included Baltimore (BWI) to St. Louis (STL) 8.2/10 Very Good! (1,003 reviews) Room was nice. Staff was very friendly Warm cookies were good Reviewed on Feb 26, 2026 ![Hotel Saint Louis, Autograph Collection](https://images.trvl-media.com/lodging/28000000/27480000/27478600/27478599/8a12cc18_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Saint Louis, Autograph Collection Downtown St. Louis $689 per person Apr 9 - Apr 12 found 17 hours ago Roundtrip non-stop flight included Baltimore (BWI) to St. Louis (STL) 8.8/10 Excellent! (458 reviews) Not the best and not the Reviewed on Feb 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Ethel [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-27/2026-04-03/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MCI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_102383) ## Ethel Hotel Deals ![Hampton Inn Kirksville](https://images.trvl-media.com/lodging/20000000/20000000/19991900/19991846/388c1302_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Kirksville 2604 N. Baltimore Street Kirksville MO Fully refundableReserve now, pay when you stay $122 nightly $138 total Mar 8 - Mar 9 Total with taxes and fees 9.2/10 Wonderful! (596 reviews) Very clean room/ bathroom. Amazing staff, and a very good breakfast! Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=19991846&PinnedHotelID=19991846&HadPinnedHotel=true®ionId=102383) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Super 8 by Wyndham Kirksville-University Area 1101 Country Club Dr Kirksville MO Fully refundableReserve now, pay when you stay $60 nightly $67 total Mar 8 - Mar 9 Total with taxes and fees 9.2/10 Wonderful! (174 reviews) The room was very clean. Check-in was super fast, and check-out was even faster. The location is excellent. For dinner we walked next door to Colton’s Steakhouse. The breakfast was good with plenty of variety. I would definitely stay here again. Reviewed on Feb 25, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=123590&PinnedHotelID=123590&HadPinnedHotel=true®ionId=102383) ![Depot Inn and Suites](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Depot Inn and Suites 1245 N. Brown St. La Plata MO Fully refundableReserve now, pay when you stay $88 nightly $96 total Mar 1 - Mar 2 Total with taxes and fees 9.8/10 Exceptional! (636 reviews) Very clean. Staff were very helpful and friendly. Reviewed on Feb 23, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=1790806&PinnedHotelID=1790806&HadPinnedHotel=true®ionId=102383) [See all 86 properties in Ethel](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=102383) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Ethel Vacation Packages ## Ethel Essential Information | Language | English | | --------------- | ---------------------------------- | | Currency | U.S dollars | | Closest Airport | Kirksville Municipal Airport (IRK) | | Max Temp Winter | 35ºF | | Max Temp Summer | 80ºF | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does an Ethel vacation package cost? ### What are the cheapest months to go to Ethel? ### How many days is enough for Ethel? ### How to find the best Ethel package deals? ### Is it cheaper to book an Ethel vacation as a package? ### When to book a vacation package to Ethel? ### Does Expedia offer Book Now, Pay Later Ethel vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [New Cambria Hotels ](https://www.expedia.com/New-Cambria-Hotels.d553248634983235487.Travel-Guide-Hotels) - [Bucklin Hotels ](https://www.expedia.com/Bucklin-Hotels.d553248634983432916.Travel-Guide-Hotels) - [Callao Hotels ](https://www.expedia.com/Callao-Hotels.d3000444667.Travel-Guide-Hotels) - [Atlanta Hotels ](https://www.expedia.com/Atlanta-Hotels.d553248634983075091.Travel-Guide-Hotels) - [Hotels near La Plata Golf Course ](https://www.expedia.com/La-Plata-Golf-Course-Hotels.0-l553248634680215491-0.Travel-Guide-Filter-Hotels) - [Hotels near La Plata Station ](https://www.expedia.com/La-Plata-Station-Hotels.d6196162.Travel-Guide-Hotels) - [Flights from Kirksville Municipal ](https://www.expedia.com/lp/airports/irk/flights-from-kirksville-municipal-airport) - [Flights from Chicago (ORD) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/ord/irk/chicago-to-kirksville) - [Flights from St. Louis (STL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/stl/irk/st-louis-to-kirksville) - [Flights from Kansas City (MCI) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mci/irk/kansas-city-to-kirksville) - [Flights from New York (NYC) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/nyc/irk/new-york-to-kirksville) - [Flights from Des Moines (DSM) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/dsm/irk/des-moines-to-kirksville) - [Flights from Dallas (DFW) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/dfw/irk/dallas-to-kirksville) - [Flights from Columbia (CAE) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/cae/irk/columbia-to-kirksville) - [Flights from Nashville (BNA) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bna/irk/nashville-to-kirksville) - [Flights from Atlanta (ATL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/atl/irk/atlanta-to-kirksville) - [Flights from Memphis (MEM) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mem/irk/memphis-to-kirksville) - [Flights from Houston (IAH) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/iah/irk/houston-to-kirksville) - [Flights from Tampa (TPA) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/tpa/irk/tampa-to-kirksville) - [Flights from Salt Lake City (SLC) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/slc/irk/salt-lake-city-to-kirksville) - [Flights from Springfield (SGF) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/sgf/irk/springfield-to-kirksville) - [Flights from Detroit (DTW) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/dtw/irk/detroit-to-kirksville) - [Flights from Hartford (BDL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bdl/irk/hartford-to-kirksville) - [Flights from Grand Junction (GJT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/gjt/irk/grand-junction-to-kirksville) - [Flights from Denver (DEN) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/den/irk/denver-to-kirksville) - [Flights from Columbus (CMH) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/cmh/irk/columbus-to-kirksville) - [Flights from Fort Lauderdale (FLL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/fll/irk/fort-lauderdale-to-kirksville) - [Flights from Boston (BOS) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bos/irk/boston-to-kirksville) - [Flights from Phoenix (PHX) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/phx/irk/phoenix-to-kirksville) - [Flights from Louisville (SDF) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/sdf/irk/louisville-to-kirksville) - [Flights from Washington (DCA) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/dca/irk/washington-to-kirksville) - [Flights from Minneapolis (MSP) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/msp/irk/minneapolis-to-kirksville) - [Flights from San Antonio (SAT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/sat/irk/san-antonio-to-kirksville) - [Flights from Charlotte (CLT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/clt/irk/charlotte-to-kirksville) - [Flights from Little Rock (LIT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/lit/irk/little-rock-to-kirksville) - [Flights from Owensboro (OWB) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/owb/irk/owensboro-to-kirksville) - [Flights from Seattle (SEA) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/sea/irk/seattle-to-kirksville) - [Flights from Los Angeles (LAX) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/lax/irk/los-angeles-to-kirksville) - [Flights from Las Vegas (LAS) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/las/irk/las-vegas-to-kirksville) - [Flights from Orlando (MCO) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mco/irk/orlando-to-kirksville) - [Flights from Houston (HOU) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/hou/irk/houston-to-kirksville) - [Flights from Joplin (JLN) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/jln/irk/joplin-to-kirksville) - [Flights from Milwaukee (MKE) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mke/irk/milwaukee-to-kirksville) - [Flights from Fargo (FAR) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/far/irk/fargo-to-kirksville) - [Flights from Rochester (ROC) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/roc/irk/rochester-to-kirksville) - [Flights from Albuquerque (ABQ) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/abq/irk/albuquerque-to-kirksville) - [Flights from Quincy (UIN) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/uin/irk/quincy-to-kirksville) - [Flights from New Orleans (MSY) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/msy/irk/new-orleans-to-kirksville) - [Flights from Philadelphia (PHL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/phl/irk/philadelphia-to-kirksville) - [Flights from Pittsburgh (PIT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/pit/irk/pittsburgh-to-kirksville) - [Flights from Baltimore (BWI) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bwi/irk/baltimore-to-kirksville) - [Flights from Indianapolis (IND) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/ind/irk/indianapolis-to-kirksville) - [Flights from Cincinnati (CVG) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/cvg/irk/cincinnati-to-kirksville) - [Flights from Birmingham (BHM) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bhm/irk/birmingham-to-kirksville) - [Flights from Pensacola (PNS) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/pns/irk/pensacola-to-kirksville) - [Contour Airlines Chicago (ORD) to Kirksville (IRK) flights ](https://www.expedia.com/lp/flight-routes/contour-airlines-from-ohare-intl-to-kirksville-municipal/lf/ord/irk) - [Flights from Tulsa (TUL) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/tul/irk/tulsa-to-kirksville) - [Flights from Raleigh (RDU) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/rdu/irk/raleigh-to-kirksville) - [Flights from Oklahoma City (OKC) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/okc/irk/oklahoma-city-to-kirksville) - [Flights from San Francisco (SFO) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/sfo/irk/san-francisco-to-kirksville) - [Flights from Greenville (GSP) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/gsp/irk/greenville-to-kirksville) - [Flights from Sacramento (SMF) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/smf/irk/sacramento-to-kirksville) - [Flights from Branson (BKG) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/bkg/irk/branson-to-kirksville) - [Flights from Portland (PDX) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/pdx/irk/portland-to-kirksville) - [Flights from Macon (MCN) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mcn/irk/macon-to-kirksville) - [Flights from Lexington (LEX) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/lex/irk/lexington-to-kirksville) - [Flights from Buffalo (BUF) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/buf/irk/buffalo-to-kirksville) - [Flights from Cleveland (CLE) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/cle/irk/cleveland-to-kirksville) - [Flights from Chicago (MDW) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mdw/irk/chicago-to-kirksville) - [Flights from Wichita (ICT) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/ict/irk/wichita-to-kirksville) - [Flights from Monroe (MLU) to Kirksville (IRK) ](https://www.expedia.com/lp/flights/mlu/irk/monroe-to-kirksville) - [Flights from Tucson (TUS) to Kirksville (IRK) 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