Most St. Louis hotels offer free cancellation. Consider booking refundable hotels rather than non-refundable ones. Just look for the ‘free cancellation’ message during your hotel search. Prices can vary, but right now we believe that flexibility matters.
For more information about the impact of COVID-19 on your St. Louis trip, please visit our Coronavirus Information page (opens in new window).
There’s nothing quite like a St. Louis road trip. And Expedia makes it easy for you to turn all those road trip ideas into reality. You can find cheap deals on hotels in St. Louis or bundle your hotels with car rentals to save even more. With our St. Louis packages, you’ll find hitting the highway for that road trip adventure is more affordable than ever.
Planning a road trip can feel daunting, especially when you’ll be making multiple bookings for your itinerary. But you can find car rentals in St. Louis and low rates on hotels all in one place— Expedia. How you plan your road trip depends on what’s important to you. People love to take road trips to experience the great outdoors, bond with friends or family and see more of the world. When planning, bundle your car rental and hotel into one discounted package to maximize savings on both. Or, leave room for spontaneity, booking what you need when you need it with our last-minute deals.
When taking a road trip adventure, it’s best to plan how you want to spend your time on your road trip itinerary. We don’t want you to miss out on any of the best things to do in St. Louis. You can book all the road trip activities on your St. Louis wishlist, and even plan activities along your route as well.
For an epic road trip, you'll need the perfect car. Renting a car for a road trip is the best option that doesn’t put miles or strain on your vehicle, and especially when it's also so affordable. Because when you book on Expedia, it doesn't need to be expensive. You can pick up a cheap car rental and head out to one of these incredible vacation rentals in St. Louis. And when you bundle car rentals with hotel stays, you'll save even more on each part of your journey.
Reviewed on Apr 13, 2021
Reviewed on May 10, 2021
Reviewed on Apr 30, 2021
4/5Very Good!(4,004 area reviews)
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.
4.5/5Wonderful!(450 area reviews)
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.
St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Lewis & Clark Boathouse and Nature Center while you're in town.
4/5Very Good!(6 area reviews)
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
Famous for its historic ice cream-colored houses and independent businesses, this characterful neighborhood is the perfect place to shop, dine and relax.
Reviewed on May 10, 2021
Reviewed on May 14, 2021
Reviewed on May 14, 2021
