Find hotels in Downtown Clayton from $104

The Ritz-Carlton, St. Louis stands out as a premier choice in Downtown Clayton, boasting a great rating of 9.2. This luxurious hotel offers an onsite spa featuring a variety of treatments, including deep tissue and hot stone massages, superb for those looking to unwind after a day of adventure. Guests appreciate the elegant touch of designer toiletries and premium bedding in their rooms, alongside amenities like valet parking and a fitness center, ensuring a comfortable and convenient stay.For families, the Residence Inn By Marriott St. Louis Clayton, also rated 9.2, is an excellent option. With complimentary breakfast and kitchen facilities in spacious suites, families can enjoy the comforts of home while traveling. The hotel's proximity to local museums and attractions makes it easy for families to plan their adventures, while pet-friendly policies ensure that no family member gets left behind.Couples seeking a romantic getaway might find the Hampton Inn & Suites Clayton/St. Louis-Galleria Area, rated 9.0, to be an ideal retreat. Featuring an indoor pool and comfortable rooms with deep soaking bathtubs, it's a superb mix of relaxation and intimacy. The hotel's central location allows couples to explore nearby dining and entertainment options, making for memorable evenings out.For business travelers, the Clayton Plaza Hotel & Extended Stay, rated 8.8, offers a professional environment with multiple meeting spaces and a 24-hour business center. Its convenient self-parking and high-speed internet ensure that work can continue smoothly during your stay. Plus, the heated indoor pool provides a great way to decompress after a busy day.Each of these hotels in Downtown Clayton caters to different needs, ensuring that every traveler finds the superb fit for their stay. With their exceptional service and array of amenities, your trip to Clayton is sure to be enjoyable and stress-free.

The Ritz-Carlton, St. Louis, rated an impressive 9.2 by guests, stands out as a premier choice for families seeking a luxurious experience in Downtown Clayton. This hotel offers thoughtful amenities such as free cribs and connecting rooms, ensuring that families can accommodate their little ones comfortably. The spacious rooms often feature sofa beds, making it easy to settle in after a day of adventure.Another excellent option is the Hampton Inn & Suites Clayton/St. Louis-Galleria Area, which also boasts a strong review score of 9.0. Families will appreciate the connecting rooms and the inviting pool area, great for a refreshing dip. Additionally, the hotel provides a free crib service and a snack bar, making it convenient for busy parents on the go.For those looking for a more extended stay, Clayton Plaza Hotel & Extended Stay, with a rating of 8.8, is a fantastic family-friendly property. It features a pool for splashing fun, connecting rooms for added space, and even an arcade game room to keep the kids entertained. Plus, the complimentary breakfast on weekdays is a great way to start the day without hassle.Le Méridien St. Louis Clayton also offers family-friendly amenities with a comfortable atmosphere. With amenities like free rollaway beds, cribs, and a pool, families can unwind and enjoy their time together. The hotel's garden area provides a peaceful retreat, and the complimentary breakfast options cater to young diners.Each of these hotels ensures a blend of quality and convenience, making them ideal for families looking to create lasting memories in Downtown Clayton.

The Residence Inn By Marriott St. Louis Clayton is an excellent choice for families seeking both comfort and convenience in Downtown Clayton. This highly-rated hotel boasts a traveler review score of 9.2, and offers a range of family-friendly amenities including complimentary full breakfast, spacious suites equipped with kitchen facilities, and free Wi-Fi, ensuring that both parents and children feel right at home.Another fantastic option is the Hampton Inn & Suites Clayton/St. Louis-Galleria Area, rated at an impressive 9.0. Families will appreciate the indoor pool, superb for a splash after a day of adventures. With free breakfast options and suites that can accommodate larger groups, this hotel makes it easy to start each day with energy and excitement.For those traveling with older children or couples, the Clayton Plaza Hotel & Extended Stay could be an appealing alternative. With an inviting indoor heated pool and a review score of 8.8, it offers a relaxing environment after a day of exploring the city.No matter which property you choose, Downtown Clayton offers a warm and inviting space for travelers, with plenty of amenities to ensure a memorable stay.

One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Downtown Clayton hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.