Clayton, MO
St. Louis
Visit Clayton
Popular places to visit
Washington University in St. Louis
Enjoy the collegiate vibe with a visit to Washington University in St. Louis, a top college in St. Louis. Amble around the area's lush forest or attend a sporting event.
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis Premium Small Group Tour With Arch & River Cruise
St. Louis Premium Driving Tour with Boat Ride & Arch
Lemp Haunted Neighborhood Walking Tour
St. Louis: Lemp Haunted Neighborhood Ghost Tour
St. Louis Small Group Tour with St. Louis Arch & River Cruise
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
"Room was clean and the parking area is connected to the hotel which is very convenient. Breakfast is added bonus. The staff is great."
Reviewed on Jun 20, 2026
Le Méridien St. Louis Clayton
"A wonderful stay. Room was clean and nice and had dinner at the on site restaurant and everything was delicious."
Reviewed on Jun 17, 2026
The Ritz-Carlton, St. Louis
"We went on Memorial Day weekend which may have been why but there were so many weddings! (7) The car park was situated so that unless you walked outside and hiked the perimeter of the property you had to navigate through wedding guests to get to your car."
Reviewed on Jun 5, 2026
AC Hotel St. Louis Clayton
"The rooftop was a"
Reviewed on Jun 15, 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
"They gave us bottle water to brush our teeth with and you have to pay everywhere to park, not quite what I expected for the lofty price."
Reviewed on Jun 18, 2026
Hyatt Regency St. Louis at The Arch
"Rooms are clean, friendly staff, few steps to go to St Louis historic arch. Not all lifts were functional. there will a long wait for lifts on busy times."
Reviewed on Jun 19, 2026
Where to stay in Clayton
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
St. Charles Historic District
St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.
Clayton, MO
Explore a world of travel with Expedia
- St. Louis Hotels
- Condo Rentals in Forsyth Station
- Hotels near Forsyth Station
- Hotels near Demun
- Hotels near Washington University in St. Louis
- Hotels near Chapel of St. Timothy And St. Titus
- Hotels near U City Big Bend Station
- Apartments in U City Big Bend Station
- Hotels near Downtown Clayton
- Richmond Heights Hotels
- Hotels with Hot Tubs in Richmond Heights
- Hotels with a Pool in Richmond Heights
- 4 Star Hotels in Richmond Heights
- Hotel Wedding Venues Hotels in Richmond Heights
- Pet-Friendly Hotels in Richmond Heights
- 5 Star Hotels in Richmond Heights
- Cheap Hotels in Richmond Heights
- Boutique Hotels in Richmond Heights
- Extended Stay Hotels in Richmond Heights
- Romantic Hotels in Richmond Heights
- Hotels & Resorts for Couples in Richmond Heights
- Family Hotels in Richmond Heights
- Villas in Richmond Heights
- Hotels near Wydown Skinker
- Hotels near Center of Creative Arts
- Hotels near Richmond Heights Station
- Hotels near Delmar Loop
- Hotels near Mildred Lane Kemper Art Museum
- Hotels near Brentwood Station
- Hotels near Saint Louis Galleria Mall
- Hotels near Skinker Station
- Hotels near St. Louis Walk of Fame
- Hotels near St. Louis Zoo
- Hotels near Tivoli Theatre
- Hotels near St. Louis Art Museum
- Hotels near University City
- Hotels near Delmar Station
- Hotels & Resorts for Couples in University City
- 3 Star Hotels in University City
- Hotels with Bars in University City
- 4 Star Hotels in University City
- Hotel Wedding Venues Hotels in University City
- Hotels near Clayton-Tamm
- Apartments in Maplewood Station
- Brentwood Hotels
- Hotels near Missouri History Museum
- Maplewood Hotels
- Hotels near Forest Park Station
- Hotels near The Focal Point
- Hotels near Dennis and Judith Jones Visitor and Education Center
- Business Hotels in Brentwood
- Condo Rentals in Brentwood
- Hotels with Balconies in Brentwood
- B&B in Brentwood
- Hotels with a Gym in Brentwood
- Hilton Hotels in Brentwood
- Villas in Brentwood
- Cabin Rentals in Brentwood
- Family Hotels in Brentwood
- Pet-Friendly Hotels in Brentwood
- Motel 6 Hotels in Brentwood
- Hotels with Laundry Facilities in Brentwood
- Hotels with Hot Tubs in Brentwood
- 5 Star Hotels in Brentwood
- 4 Star Hotels in Brentwood
- Hotels with a Pool in Brentwood
- Red Carpet Inn Hotels in Brentwood
- Visit Richmond Heights
- Chapel of St. Timothy And St. Titus
- Washington University in St. Louis
- St. Louis Zoo
- St. Louis Art Museum
- St. Louis Walk of Fame
- Visit University City
- Saint Louis Galleria Mall
- Tivoli Theatre
- Turtle Playground
- The Muny Theater
- Missouri History Museum
- The Focal Point
- Jewel Box
- Brentwood Vacations
- Car rentals near Washington University in St. Louis
- Midsize Car Rentals near Washington University in St. Louis
- Car rentals near Richmond Heights
- Car rentals near Delmar Loop
- Car rentals near Saint Louis Galleria Mall
- Car rentals near University City
- Car rentals near St. Louis Zoo
- Minivan Car Rentals near St. Louis Zoo
- Car rentals near Maplewood
- Car rentals near Brentwood
- Avis Rental Cars in Brentwood
