Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Rochester

Best deal Best deal Jul 6 - Jul 8
Tonight Tonight Jun 20 - Jun 21
This weekend This weekend Jun 22 - Jun 24
Next weekend Next weekend Jun 29 - Jul 1

Featured Rochester Hotel with a Concierge

See all 168 Properties in Rochester
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

101 1st Ave Sw, Rochester
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
4.2 out of 5 (202 reviews)
Nice hotel located in the hear of Mayo ClinicWe were in town for a wedding and decided to stay at the Mayo Clinic Marriott as we were familiar with the area. Being in walking distance to bars and restaurants was a huge plus
Jun 18, 2018

Marriott Rochester Mayo Clinic$149

Marriott Rochester Mayo Clinic$149
Aspen Suites

Aspen Suites

1211 2nd Street, Rochester
  • Free Cancellation
  • Reserve now, pay when you stay
3.0 out of 5.0
 
 
4.3 out of 5 (185 reviews)
Almost Not exactly a family friendly hotel. The breakfast was very lacking in terms of what you would expect from a “hot breakfast.” I do not think the hotel is meant to cater to families however, so cannot fault them for not being overly family friendly.
Mar 17, 2018

Aspen Suites$145

Aspen Suites$145
Broadway Plaza

Broadway Plaza

15 1st Street Southeast, Rochester
    3.0 out of 5.0
     
     
    4.5 out of 5 (36 reviews)
    Mayo Clinic best stayRented a two bedroom, instantly felt like home. Room is spacious, concierge very helpful, stayed for 10 nights here.
    Nov 12, 2017
    Hampton Inn Rochester

    Hampton Inn Rochester

    1755 S Broadway, Rochester
    • Free Cancellation
    • Reserve now, pay when you stay
    2.5 out of 5.0
     
     
    4.5 out of 5 (349 reviews)
    Best hotel Kind and great staff, hotel is clean and in great condition. There's complimentary breakfast and soap. This helped us so much and is so grateful for this because we were at the Mayo Clinic every day and were tight on money. They also have a nice coffee bar and fresh fruit every day. I'm telling this ...
    Apr 12, 2018

    Hampton Inn Rochester$94

    Hampton Inn Rochester$94
    Kahler Grand Hotel

    Kahler Grand Hotel

    20 2nd Ave Sw, Rochester
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     
    3.4 out of 5 (1,946 reviews)
    Across the street from Mayo ClinicWe have stayed here numerous times. It isn't the cheapest hotel around but with Senior discounts that you can get through several different services, it is affordable. It is always a pleasant place to stay as it is clean and quiet. The beds are comfortable and the staff is friendly. Drop down on ...
    Jun 14, 2018

    Kahler Grand Hotel$45

    Kahler Grand Hotel$45
    La Quinta Inn & Suites Rochester

    La Quinta Inn & Suites Rochester

    4353 Canal Pl SE, Rochester
    • Free Cancellation
    • Reserve now, pay when you stay
    3.0 out of 5.0
     
     
    4.5 out of 5 (346 reviews)
    Comfortable hotel near Mayo Clinic This hotel had very comfortable beds and the bathroom door was wide enough to accommodate a wheel chair. There was a Deaf accessible light when someone knocked on the door. The staff were very friendly and there was a courtesy bus to the clinic, if needed. The pool was awesome! The only drawback ...
    Jun 16, 2018

    La Quinta Inn & Suites Rochester$93

    La Quinta Inn & Suites Rochester$93
    Weekend Special! $295/ Night June 15-18

    Weekend Special! $295/ Night June 15-18

    , Preston
       
       
      4.9 out of 5 (22 reviews)
      Beautiful and comfortable home!The house is charming and roomy, perfect for a group of people. Conveniently located near the bike trail. The beds are extremely comfortable, and the bedding is impeccable. Tara was accessible to help us out if needed. Would definitely rent again!
      Sep 18, 2017
      The Towers At Kahler Grand Hotel

      The Towers At Kahler Grand Hotel

      20 2nd Ave SW, Rochester
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.8 out of 5 (9 reviews)
      The Kayler Tower Hotel is lovelyWe usually stay club level at the Marriott when we are in Rochester, but decided to try The Kayler Tower Hotel for our current trip. We loved it and this will be our new place to stay. The Kayler Tower hotel is beautiful and the club far exceeded our expectations. The club level staff is extremely ...
      Feb 22, 2018

      The Towers At Kahler Grand Hotel$459

      The Towers At Kahler Grand Hotel$459
      Map

      Recently booked Hotel with a Concierge in Rochester

      Days Inn & Suites by Wyndham Rochester South
      2.5 out of 5.0
      Last booking: 17 minutes ago
      Brentwood Inn & Suites
      2.5 out of 5.0
      Last booking: 31 minutes ago
      Microtel Inn & Suites by Wyndham Rochester South
      3.0 out of 5.0
      Last booking: 1 hour ago
      Rodeway Inn & Suites
      2.0 out of 5.0
      Last booking: 2 hours ago
      Kahler Inn and Suites - Mayo Clinic Area
      3.5 out of 5.0
      Last booking: 4 hours ago
      Homewood Suites by Hilton Rochester-Saint Marys& Mayo Clinic
      3.0 out of 5.0
      Last booking: 5 hours ago
      Kahler Grand Hotel
      3.0 out of 5.0
      Last booking: 5 hours ago
      SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
      3.0 out of 5.0
      Last booking: 5 hours ago
      Staybridge Suites Rochester - Commerce Dr NW
      3.0 out of 5.0
      Last booking: 5 hours ago

      Pocket Guide: Hotel with a Concierge in Rochester

      Search for hotels in Rochester on Expedia. You can easily find your hotels in Rochester using one of the methods below:

      • View our selection of featured hotels in Rochester
      • Use the map to find hotels in the Rochester neighborhood you prefer
      • Use the filters to see hotels in a specific area of Rochester, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Rochester
      • Enter your travel dates to view the best deals on hotels in Rochester - while they last