Find hotels near Mayo Clinic, Rochester from $72

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Compare 421 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Rochester Mayo Clinic Area

3.5 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
9.6 out of 10, Exceptional, (540)
"Had a great stay. Room was very clean and staff was very courteous. "
United States
Bonita
$171 nightly
The price is $197
Dec 12 - Dec 13
Total with taxes and fees
Hilton Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
9.6 out of 10, Exceptional, (480)
"Overall great place"
United States
Jill
$118 nightly
The price is $136
Dec 12 - Dec 13
Total with taxes and fees
TownePlace Suites by Marriott Rochester Mayo Clinic Area

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

2.5 star property
Kutzky Park, 1.1 mi from Mayo Clinic
9.6 out of 10, Exceptional, (672)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
$98 nightly
The price is $113
Dec 21 - Dec 22
Total with taxes and fees
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

The Berkman

3.0 star property
Folwell, 0.9 mi from Mayo Clinic
9.6 out of 10, Exceptional, (367)
"Perfect location for visit to hospital. "
United States
Sharon
$177 nightly
The price is $203
Dec 5 - Dec 6
Total with taxes and fees
The Berkman

Home2 Suites by Hilton Rochester Mayo Clinic Area

3.0 star property
1.6 mi from Mayo Clinic
9.6 out of 10, Exceptional, (877)
"Everything was perfect!!"
United States
Lori
$114 nightly
The price is $131
Dec 11 - Dec 12
Total with taxes and fees
Home2 Suites by Hilton Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
1.6 mi from Mayo Clinic
9.6 out of 10, Exceptional, (241)
"Great place"
United States
Steve
$119 nightly
The price is $137
Dec 12 - Dec 13
Total with taxes and fees
Residence Inn by Marriott Rochester Mayo Clinic Area South

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
Kutzky Park, 0.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (950)
"Hotel was spotless, excellent staff and the breakfast was excellent. Late night eats at the restaurant and the food served was fantastic."
United States
Carmino
$89 nightly
The price is $102
Dec 26 - Dec 27
Total with taxes and fees
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

3.0 star property
Kutzky Park, 0.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (416)
"Breakfast is great, staff is chill, place is clean, comfortable. "
United States
Sarah
$97 nightly
The price is $112
Dec 26 - Dec 27
Total with taxes and fees
Staybridge Suites Rochester - Mayo Clinic Area by IHG

The Towers At Kahler Grand Hotel

4.0 star property
Downtown Rochester, < 0.1 mi from Mayo Clinic
9.4 out of 10, Exceptional, (93)
"Everything was wonderful."
United States
Shannon
$399 nightly
The price is $460
Dec 5 - Dec 6
Total with taxes and fees
The Towers At Kahler Grand Hotel

Candlewood Suites Rochester Mayo Clinic Area by IHG

2.5 star property
1.6 mi from Mayo Clinic
9.4 out of 10, Exceptional, (449)
"Convenient location "
United States
Tammy
$87 nightly
The price is $100
Dec 12 - Dec 13
Total with taxes and fees
Candlewood Suites Rochester Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

3.0 star property
Downtown Rochester, 0.3 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1000)
"They were great letting us check in early. "
United States
steven
$129 nightly
The price is $149
Dec 20 - Dec 21
Total with taxes and fees
Hyatt House Rochester/Mayo Clinic Area

Broadway Plaza, Trademark Collection by Wyndham

3.0 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
$140 nightly
The price is $161
Dec 6 - Dec 7
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3.0 star property
Kutzky Park, 0.9 mi from Mayo Clinic
9.2 out of 10, Wonderful, (474)
"Very good stay so far. The parking area is very icy and needs salt"
United States
Ryan
$103 nightly
The price is $119
Dec 19 - Dec 20
Total with taxes and fees
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

3.0 star property
Kutzky Park, 0.9 mi from Mayo Clinic
9.0 out of 10, Wonderful, (764)
"Clean room and housekeeping service was excellent"
United States
Dawn
$84 nightly
The price is $97
Dec 21 - Dec 22
Total with taxes and fees
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Aspen Suites

3.0 star property
0.8 mi from Mayo Clinic
9.0 out of 10, Wonderful, (685)
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
$137 nightly
The price is $158
Dec 12 - Dec 13
Total with taxes and fees
Aspen Suites

Hampton Inn Rochester-South

2.5 star property
1.8 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1004)
"We had a wonderful stay!"
United States
Sarah
$82 nightly
The price is $95
Dec 26 - Dec 27
Total with taxes and fees
Hampton Inn Rochester-South

Econo Lodge Mayo Clinic Area

2.0 star property
1.9 mi from Mayo Clinic
9.0 out of 10, Wonderful, (889)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
$63 nightly
The price is $72
Dec 19 - Dec 20
Total with taxes and fees
Econo Lodge Mayo Clinic Area

Hilton Garden Inn Rochester Downtown, MN

3.0 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (846)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
$107 nightly
The price is $123
Dec 12 - Dec 13
Total with taxes and fees
Hilton Garden Inn Rochester Downtown, MN

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (881)
"Great room and stay!"
United States
Trevor
$67 nightly
The price is $77
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Brentwood Inn & Suites

2.5 star property
Downtown Rochester, 0.2 mi from Mayo Clinic
8.8 out of 10, Excellent, (1005)
"Room was clean breakfast was good everybody was helpful "
United States
james
$125 nightly
The price is $144
Dec 5 - Dec 6
Total with taxes and fees
Brentwood Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mayo Clinic Hotel Reviews

Hotels near other Mayo Clinic attractions

Frequently asked questions

What are the top-rated hotels near Mayo Clinic?
Discovering the top-rated hotels near Mayo Clinic ensures a comfortable and convenient stay during your visit to Rochester, Minnesota.

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area is a welcoming 3-star hotel located just 2.8 miles from Mayo Clinic, rated 9.6 by travelers. Guests appreciate the modern amenities, including a kitchenette with a dishwasher and microwave, as well as a cozy sofa bed. The hotel features complimentary daily breakfast and an accessible indoor pool, making it a perfect choice for those seeking a relaxed atmosphere. With additional perks like Egyptian cotton sheets and a fitness center, this hotel ensures comfort and convenience for every traveler.

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South is another excellent option, situated 2.8 miles from Mayo Clinic and a review rating of 9.6. This 3-star hotel offers spacious rooms with full kitchens and a convenient wet bar, ideal for longer stays. Guests can enjoy a complimentary breakfast and take advantage of the indoor pool and hot tub. The fitness center is accessible 24 hours, ensuring travelers can maintain their routine while away from home.

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys is perfectly located just 1.5 miles from Mayo Clinic, earning an impressive review rating of 9.6. This hotel features comfortable suites and an inviting atmosphere, complete with an indoor pool and a rooftop garden for relaxation. Guests can enjoy complimentary breakfast and easy access to an onsite tennis court, making it a great choice for those looking to stay active during their visit.
What hotels are within walking distance to Mayo Clinic?
Discover the convenience of top-rated hotels within walking distance to Mayo Clinic, perfect for travelers seeking comfort and accessibility.

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area is a welcoming 3.5-star hotel located just a 6-minute walk from Mayo Clinic, with an impressive review rating of 9.6. This hotel features an indoor pool, a full-service spa offering massages and aromatherapy treatments, and a fitness center open 24 hours. Guests can also enjoy relaxing moments in the hot tub and steam room, making it an excellent choice for relaxation after a day at the clinic.

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area is a cozy 3-star hotel that is only a 5-minute stroll from Mayo Clinic, rated 9.6 by travelers. It offers a complimentary buffet breakfast and 24-hour fitness facilities. Guests appreciate the rooftop garden and the convenience of in-room kitchens, perfect for those looking to prepare their own meals. The hotel also provides free area shuttle services, adding to its overall convenience for travelers.

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG is a comfortable 3-star hotel located a 12-minute walk from Mayo Clinic, with a solid review rating of 9.4. This hotel features an indoor pool and a hot tub, along with spacious suites equipped with kitchens and premium bedding. Guests can enjoy a complimentary breakfast daily and take advantage of the free area shuttle service, making it an ideal base for those visiting the clinic.
How much is a hotel near Mayo Clinic?
Staying near Mayo Clinic is a treat, with plenty of hotels from $72 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Mayo Clinic?
For families visiting Mayo Clinic, finding the perfect family-friendly hotel is essential for a comfortable stay. Here are some of the top-rated options that cater to families.

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Located just an 8-minute walk from Mayo Clinic, the Centerstone Plaza Hotel Soldiers Field is a family-friendly haven with a review rating of 8.4 and a 3-star rating. This hotel features an indoor pool with a children's area, free daily breakfast, and kitchens in select rooms, perfect for families. Guests will appreciate the comfortable accommodations and easy access to the clinic.

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites offers an inviting atmosphere just 1.3 miles from Mayo Clinic, perfect for families. With a great traveler rating score of 8.0, this hotel features a fantastic waterslide and a children's pool to keep the little ones entertained. Guests can also enjoy complimentary breakfast, a kitchenette in the rooms, and a game room designed for family fun, ensuring a memorable stay.

Kahler Grand Hotel

Just a 3-minute walk from Mayo Clinic, Kahler Grand Hotel is an ideal family-friendly choice with a review rating of 8.2 and a 3-star rating. Families will enjoy amenities like free cribs, connecting rooms, and a children's menu at the on-site restaurant. With its indoor pool and convenient location, travelers can easily balance relaxation and access to the clinic.
What are the best affordable hotels near Mayo Clinic?
Finding a budget-friendly hotel near Mayo Clinic can enhance your stay and provide peace of mind during your visit. Here are some top-rated options that offer great amenities without breaking the bank.

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area is a 3-star hotel located just 2.8 miles from Mayo Clinic, with an impressive review rating of 9.6. This family-friendly hotel features complimentary breakfast daily, including a buffet on weekends, and offers a variety of amenities such as a fitness center, free WiFi, and a kitchenette in each suite. Guests can also enjoy the convenience of free area shuttle service and on-site grocery shopping service.

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South is another excellent 3-star option, situated 2.8 miles from Mayo Clinic with a stellar review rating of 9.6. Ideal for families, this hotel features a complimentary continental breakfast and an indoor pool perfect for relaxation. Guests will appreciate the fully equipped kitchens in the suites, free WiFi, and accessible fitness facilities to maintain their routine while traveling.

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys stands out with a prime location just 1.5 miles from Mayo Clinic and a popular review rating of 9.6. This family-friendly hotel offers free breakfast options and access to an indoor pool, making it a great choice for leisure and relaxation. Additional amenities include free parking, WiFi, and a fitness center, ensuring travelers have all they need for a comfortable stay.
Are there any hotels with pools close to Mayo Clinic?
If you're looking for hotels with pools near Mayo Clinic, Rochester offers some great options that cater to travelers seeking relaxation and comfort during their stay.

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area is located only 8 minutes from Mayo Clinic and has an excellent review rating of 8.4. This hotel offers an indoor pool with features for children and accessibility options. Guests can also take advantage of free buffet breakfast, 24-hour fitness facilities, and easy access to nearby golf courses and historical sites.

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's is conveniently located just 2.2 miles from Mayo Clinic, making it an ideal choice for travelers. With an impressive review rating of 8.2, this hotel features an indoor pool complete with a waterslide and children's area—perfect for families. Guests can also enjoy free breakfast, a hot tub, and easy access to local golf courses.

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area is just a 3-minute walk from Mayo Clinic and boasts a great traveler rating score of 7.8. This family-friendly hotel features an indoor pool with accessibility options, making it suitable for everyone. Guests can enjoy amenities like a kitchenette in the rooms, free breakfast, and covered parking, ensuring a comfortable stay.
What are the best pet-friendly hotels near Mayo Clinic?
For travelers seeking pet-friendly accommodations near the Mayo Clinic, these top-rated hotels offer welcoming stays for both you and your furry friend.

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott stands out with an impressive 9.6 travelers' rating and is located 2.8 miles from the Mayo Clinic. This 3-star hotel allows both dogs and cats, making it a perfect choice for travelers with pets. Guests will appreciate the complimentary breakfast, an indoor pool, and a fitness center. Additional features include a fully equipped kitchen in every suite and convenient parking options.

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field is just an 8-minute walk from the Mayo Clinic and has a welcoming atmosphere for pets, earning a review rating of 8.4. This 3-star hotel features an indoor pool, free buffet breakfast, and a fitness center. Guests can also enjoy nearby golf, a terrace, and family-friendly amenities such as cribs and kid-friendly meals.

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites is a cozy and inviting option just 1.3 miles from the Mayo Clinic, with a solid review rating of 8.0. This pet-friendly hotel welcomes dogs and offers essential amenities like free breakfast, an indoor pool, and a hot tub, ensuring a comfortable stay. Guests can also enjoy a fitness center, kitchenette options, and complimentary toiletries.
Can I book a fully refundable hotel close to Mayo Clinic?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mayo Clinic", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.
Can I find Expedia discounts for hotels near Mayo Clinic?
To look for discounts on hotels near Mayo Clinic, join One Key™—our free travel rewards program. One Key members always get our best prices and earn OneKeyCash™* on eligible bookings for every dollar spent. Another way to save is by bundling your hotel and flights together on Expedia.

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