Located close to Palace of Justice and Via Cola di Rienzo, Hotel Isa provides a rooftop terrace, a coffee shop/cafe, and a garden. Stay connected with free in-room WiFi, with speed of 50+ Mbps, and guests can find other amenities such as dry cleaning/laundry services and a fireplace in the lobby.
Located in Rome City Centre, a neighborhood in Rome, Hotel Isa is near a metro station. Castel Sant'Angelo and Vatican Museums are cultural highlights, and some of the area's notable landmarks include Palace of Justice and Piazza del Popolo. Via Cola di Rienzo and Tiber River are two other places to visit that come recommended. Visit our Rome travel guide
Via Cicerone 39, Rome, RM, 00186
What's nearby
Via Cola di Rienzo
2 min walk - 0.1 miles
Castel Sant'Angelo
8 min walk - 0.5 miles
Piazza del Popolo
8 min walk - 0.5 miles
Piazza di Spagna
15 min walk - 0.8 miles
Pantheon
18 min walk - 1.0 mile
Getting around
Lepanto Station
10 min walk
Rome Piazzale Flaminio Station
14 min walk
Fiumicino - Leonardo da Vinci Intl. Airport (FCO)
41 min drive
Restaurants
Visconti Palace Rooftop Bar
3 min walk
Malaterra
1 min walk
Su&giú
2 min walk
pizza dai cinque
3 min walk
l'officina della pizza
1 min walk
About this property
Hotel Isa
Upscale boutique hotel near Via Cola di Rienzo
Located close to Palace of Justice and Castel Sant'Angelo, Hotel Isa provides a rooftop terrace, a coffee shop/cafe, and a garden. Stay connected with free in-room WiFi, with speed of 50+ Mbps, and guests can find other amenities such as dry cleaning/laundry services and a fireplace in the lobby.
Additional perks include:
A roundtrip airport shuttle (surcharge), a 24-hour front desk, and tour/ticket assistance
An elevator, luggage storage, and a porter/bellhop
A banquet hall, a vegetable garden, and a front-desk safe
Guest reviews say great things about the bar, breakfast, and helpful staff
Room features
All 54 individually furnished rooms feature thoughtful touches such as air conditioning, in addition to amenities like free WiFi and safes. Guest reviews say good things about the clean rooms at the property.
Yes, this property allows cats and dogs (limit 1 total). There's a fee of EUR 15 per pet, per day. Service animals are exempt from fees.
How much does it cost to stay at Hotel Isa?
As of Oct 23, 2026, prices found for a 1-night stay for 2 adults at Hotel Isa on Nov 15, 2026 start from $219, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
What time is check-in at Hotel Isa?
Check-in start time: 3:00 PM; Check-in end time: 12:30 AM. Late check-in is available during limited hours.
What time is check-out at Hotel Isa?
Check-out is at 11:00 AM.
Does Hotel Isa provide a shuttle to the airport?
Yes, there's an airport shuttle. A fee of EUR 60 per vehicle applies.
Where is Hotel Isa located?
This family-friendly Rome hotel is located in the historical district, within a 10-minute walk of Via Cola di Rienzo, Palace of Justice, and Castel Sant'Angelo. Tiber River and Piazza del Popolo are also within 10 minutes. Lepanto Station is 10 minutes by foot and Flaminio - Piazza del Popolo Station is 11 minutes.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on select room rates, because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
Hotel Isa Reviews
9.4
Exceptional
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
The room was clean and comfortable. The rooftop bar was a very nice amenity, and the breakfast buffet was wonderful. The hotel is located in a nice area, and it's only a short walk to many good restaurants. We would definitely stay here again.
This was our third stay at Hotel Isa. The property is a charming boutique hotel, with rooftop bar that you see Vatican from. The staff is wonderful. So nice and helpful. This Hotel is a true gem.
Breakfast featured an omelet/egg station, bacon, juices, cereals, pastries, etc. Food was excellent.
Room was 3x the size of a more expensive hotel in Florence (Hotel Orto de Medici).
The day manager, a woman whose name is can't recall, was WONDERFUL.
Comfortable couches in a sitting area.
I'd definitely stay there again if I ever return to Rome.
Hotel Isa is a small, beautifully appointed family run boutique hotel. Excellent location in charming Prati,a 15 minute walk to Piazza Navona and far enough away from the noise and crowds. Rooms are spacious and comfortable, with AC. The outdoor rooftop bar and breakfast restaurant are gorgeous, with beautiful view of the Vatican. Excellent breakfast.
Beautiful higher end hotel with someone always at front desk and very helpful staff. We arrived early and our room was ready. Great location! You could easily walk to most of the area sights. The rooftop bar with a perfect view of the Vatican at night was spectacular.
Great stay. Lovely place. The staff were all very kind and gracious. Super grateful for Stefano! He was exceptional. And the breakfast was delicious! Grazie mille!!
Very nice staff and hotel. The room was nice, clean with a small balcony. The only thing that could have been better was the air conditioning was turned all the way down, but the room never felt very cool. Very nice place to stay and I would stay there again.
Wonderful hotel in the Prati area. Hotel is close to many tourist places in Rome like Trevi Fountain, Pantheon and Vatican. What I liked the most of this hotel was the breakfast it had a great variety and wonderful service. They even make eggs the way you want them. The view while having breakfast was awesome wish I could stay there longer time.
Beautiful view from the bar/breakfast area. The staff were so warm and friendly. Breakfast was high quality with an incredible selection. Bed was very comfortable. Location was perfect for touring Roma. We will definitely return when in Roma.
We had an incredible stat at Hotel Isa. The room was comfortable and spotless, the Staff was so friendly and helpful, and the view from the terrace was amazing (we went up there to hang out every night). Also, breakfast was great. We would highly recommend Hotel Isa to anyone visiting Rome and home to come back and stay there again. Thanks!
Unique boutique hotel, the roof top garden & 360 viewing deck are exceptional! We enjoyed a full breakfast buffet each day & sunset glass of vino. The staff were very responsive to questions, recommendations, & our airport shuttle service was seamless. Definitely will stay again and recommend!
The hotel is in a nice section of Rome near the Vatican. There are plenty of restaurants in walking distance. The hotel is very clean and the staff is friendly. The roof top patio with bar and complimentary breakfast was our favorite place to start and end our day.
The hotel was lovely. The breakfast was wonderful with a beautiful view. The room was clean and all the amenities you need. The staff was extremely helpful and nice and friendly. Wonderful little hotel in a great location.