Find hotels near Saint Francis Healthcare System, Cape Girardeau from $68

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Compare 220 hotels close to Saint Francis Healthcare System with room rates, reviews, and availability. Most hotels are fully refundable.

Lobby
Quality Inn
Quality Inn
2.5 star property
7.2 out of 10, Good, (653)
"nice stay"
Brandon
$60 nightly
The price is $68
Nov 6 - Nov 7
Total with taxes and fees
Quality Inn
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1019)
"Great place"
Eric
$90 nightly
The price is $102
Oct 26 - Oct 27
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau
Tru By Hilton Cape Girardeau
2.5 star property
9.6 out of 10, Exceptional, (79)
"Property is new and very modern - great breakfast"
Betty
$98 nightly
The price is $111
Oct 26 - Oct 27
Total with taxes and fees
Tru By Hilton Cape Girardeau
Desk, free WiFi
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 star property
6.0 out of 10, (198)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
Gary
$68 nightly
The price is $76
Oct 19 - Oct 20
Total with taxes and fees
Town House Inn Cape Giradreau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1009)
"Staff was very friendly and helpful would stay again "
Keith
$70 nightly
The price is $79
Oct 19 - Oct 20
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
Business center
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (1005)
"Excellent place. Really friendly staff"
Alex
$90 nightly
The price is $102
Oct 26 - Oct 27
Total with taxes and fees
Drury Inn & Suites Cape Girardeau
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
9.4 out of 10, Exceptional, (1004)
"It was right off the interstate with lots of restaurant options "
Kelly
$95 nightly
The price is $107
Oct 26 - Oct 27
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Courtyard
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (756)
"The property staff were lovely and the hotel was clean and renovated!"
Mary
$106 nightly
The price is $119
Oct 26 - Oct 27
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn
Rockwood Inn
2.0 star property
10.0 out of 10, Exceptional, (16)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
Vanessa
$150 nightly
The price is $170
Oct 19 - Oct 20
Total with taxes and fees
Rockwood Inn
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
8.8 out of 10, Excellent, (635)
"We had a restful stay very safe & clean! Friendly staff:)"
Rachel
$84 nightly
The price is $91
Oct 20 - Oct 21
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
9.4 out of 10, Exceptional, (131)
"Excellent hotel…"
Danny
$93 nightly
The price is $105
Oct 26 - Oct 27
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby
Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape Girardeau
2.5 star property
8.2 out of 10, Very Good, (736)
"Great area, fast check in, quiet, very spacious"
Jeanne
$89 nightly
The price is $96
Oct 19 - Oct 20
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau
Lobby
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (455)
"The Staff was friendly The restaurant was good"
Sirron
$125 nightly
The price is $142
Nov 2 - Nov 3
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
Lobby sitting area
The Riverview
The Riverview
4.0 star property
9.4 out of 10, Exceptional, (433)
"Location was perfect for family weekend!"
Kelly
$114 nightly
The price is $129
Oct 19 - Oct 20
Total with taxes and fees
The Riverview
Lobby
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1009)
"Close to the interstate so easy to get to when traveling. Nice property - plus that Outback Steakhouse is right next door for dining. We have stayed here numerous times over the years and always pleased. "
Janice
$70 nightly
The price is $79
Oct 19 - Oct 20
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
Exterior
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
8.0 out of 10, Very Good, (856)
"Great staff and convenient location "
Greg
$77 nightly
The price is $92
Nov 16 - Nov 17
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG
Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets
Town House Inn
Town House Inn
2.5 star property
7.6 out of 10, Good, (418)
"It was easy and quiet and an easy check in "
Heather
$70 nightly
The price is $76
Oct 19 - Oct 20
Total with taxes and fees
Town House Inn
Lobby
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (1015)
"Great service! Definitely will stay there again!"
David
$90 nightly
The price is $95
Oct 22 - Oct 23
Total with taxes and fees
Drury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Saint Francis Healthcare System Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Everything was great especially the staff "
Shareigha 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

Hotels near other Saint Francis Healthcare System attractions

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Cape Splash Family Aquatic Center

Bring the family to Cape Splash Family Aquatic Center and enjoy this exciting amusement park in Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Saint Francis Healthcare System?
Saint Francis Healthcare System is located in Cape Girardeau. This family-friendly area is known for its array of dining options. You'll find 59 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Saint Francis Healthcare System?
Quality Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.5 mi (0.8 km) from Saint Francis Healthcare System. Other good options within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau.
How many hotels should I expect to find near Saint Francis Healthcare System?
Expedia has 59 hotels and other accommodations a few miles from Saint Francis Healthcare System.
If I need to cancel the hotel reservation for my stay near Saint Francis Healthcare System, will I receive a refund?
Yes, the majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Saint Francis Healthcare System.
Where can I learn more about changing or cancelling my trip in the area near Saint Francis Healthcare System?
To find more details about updating your stay near Saint Francis Healthcare System or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Saint Francis Healthcare System?
You might spend a leisurely day outdoors at Cape Rock Park and Fort D Historic Site. Cape Splash Family Aquatic Center, Cape Girardeau Conservation Nature Center, and Lazy L Safari Park are fun stops for the whole family while you're in town. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.