Find spa resorts & hotels in Santo Spirito, Florence from $123

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Our top choices for Santo Spirito hotels with a spa

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Historic Centre of Florence
10.0 out of 10, Exceptional, (25 reviews)
  • cleanliness
    Rejuvenate with deep-tissue or Swedish massages at this elegant B&B near Piazza Santo Spirito.
$295 nightly
The price is $338
Apr 29 - Apr 30
Total with taxes and fees
SPIRIT OF FLORENCE Boutique Rooms

Agriturismo Fattoria Lavacchio

Agriturismo Fattoria Lavacchio
Pontassieve
9.6 out of 10, Exceptional, (74 reviews)
  • cleanliness
    Tuscan farm stay offers vineyard views, spa indulgences, and a seasonal outdoor pool for an enchanting escape in the countryside.
$126 nightly
The price is $141
Apr 21 - Apr 22
Total with taxes and fees
Agriturismo Fattoria Lavacchio

Villa Cora

Villa Cora
5.0 star property
Oltrarno
9.8 out of 10, Exceptional, (473 reviews)
  • cleanliness
    Rejuvenating spa escapes await at this Beaux Arts hotel with outdoor pool, sauna, and luxurious body treatments.
$828 nightly
The price is $930
Apr 29 - Apr 30
Total with taxes and fees
Villa Cora

Podere di Moiata

Podere di Moiata
Vicchio
8.8 out of 10, Excellent, (3 reviews)
  • cleanliness
    Relax in this Italian farm stay's tranquil spa, featuring soothing massage treatments, a hot tub, and a private garden escape.
$130 nightly
The price is $147
Apr 26 - Apr 27
Total with taxes and fees
Podere di Moiata

Tenuta Moriano

Tenuta Moriano
Montespertoli
10.0 out of 10, Exceptional, (6 reviews)
  • cleanliness
    Tuscan farmhouse spa with seasonal pools and winery tours provides deep massage treatments in serene garden setting.
$178 nightly
The price is $200
Apr 28 - Apr 29
Total with taxes and fees
Tenuta Moriano

COMO Castello Del Nero

COMO Castello Del Nero
5.0 star property
Barberino Tavarnelle
9.6 out of 10, Exceptional, (134 reviews)
  • cleanliness
    Surrender to blissful wellness in a Tuscan retreat where hot stone massages and aromatherapy treatments await in couples' spa rooms.
$844 nightly
The price is $937
Apr 28 - Apr 29
Total with taxes and fees
COMO Castello Del Nero

Villa il Poggiale - Dimora Storica

Villa il Poggiale - Dimora Storica
San Casciano in Val di Pesa
9.6 out of 10, Exceptional, (146 reviews)
  • cleanliness
    Relax in a historic Tuscan villa with couples spa treatments, Turkish bath, and tranquil garden setting for the ultimate wellness retreat.
$139 nightly
The price is $154
Apr 29 - Apr 30
Total with taxes and fees
Villa il Poggiale - Dimora Storica

Country Hotel Borgo Sant'Ippolito

Country Hotel Borgo Sant'Ippolito
4.0 star property
Lastra a Signa
9.0 out of 10, Wonderful, (259 reviews)
  • cleanliness
    Escape to a Tuscan countryside retreat where luxurious spa treatments and garden views create a peaceful sanctuary.
$107 nightly
The price is $123
Apr 25 - Apr 26
Total with taxes and fees
Country Hotel Borgo Sant'Ippolito

Tenuta di Sticciano

Tenuta di Sticciano
Certaldo
9.6 out of 10, Exceptional, (16 reviews)
  • cleanliness
    Tuscan countryside retreat with tranquil spa services and dual outdoor pools beckons with a wine estate experience.
$160 nightly
The price is $183
Apr 21 - Apr 22
Total with taxes and fees
Tenuta di Sticciano

Viesca Toscana Suites & Villas

Viesca Toscana Suites & Villas
Reggello
9.2 out of 10, Wonderful, (7 reviews)
  • cleanliness
    Serene spa retreat in the Tuscan countryside offers deep-tissue and hot stone massages in three tranquil treatment rooms.
$274 nightly
The price is $304
Apr 26 - Apr 27
Total with taxes and fees
Viesca Toscana Suites & Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Santo Spirito

Find out more about Santo Spirito

Top Santo Spirito attractions for a relaxing vacation

In the charming Santo Spirito neighborhood of Florence, travelers seeking an indulgent spa experience will find more than just luxurious hotels; they will discover a vibrant blend of culture and relaxation. Begin your day with a visit to the Basilica di Santo Spirito, where you can admire the stunning Renaissance architecture before enjoying a peaceful stroll through the nearby Oltrarno district, known for its artisan workshops and authentic local atmosphere. For a unique cultural twist, consider a cooking class at a local culinary school, allowing you to unwind while learning to prepare traditional Tuscan dishes. After a day of exploration, retreat to one of the area’s exquisite hotels featuring full-service spas, where you can indulge in rejuvenating treatments using local ingredients. Many hotels here also offer rooftop terraces with sweeping views of Florence, perfect for sipping a glass of Chianti as the sun sets over the historic skyline. With attentive service and premium rooms, your stay in Santo Spirito will provide the perfect balance of relaxation and adventure.

Top Santo Spirito Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Santo Spirito?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Travelers like the riverfront in Santo Spirito. Take in the culture at the art galleries and monuments during your stay. Spa hotels are a great way to break away from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Santo Spirito?
Della Calza Spa & Foresteria is a top spa hotel featuring a bar, an indoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, body treatments, and couples treatments.
How many spa hotels are there in Santo Spirito?
Among Expedia's 474 accommodation options in Santo Spirito, there is 1 spa hotel.
What's there to see and do in Santo Spirito?
Experience all that Santo Spirito has to offer when you visit Piazza Santo Spirito, Santo Spirito Basilica, and Arno River. If you have extra time while you're in the area, you might want to see Torrigiani Garden and Piazza del Carmine.
What is a Santo Spirito spa hotel?
Spa hotels in Santo Spirito have full on-site spas which offer services including therapies and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

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