Santo Spirito
Florence
Visit Santo Spirito
Stay near popular Santo Spirito attractions
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$28
per adult
76% of travellers recommend
The Best of Tuscany Tour: Siena, San Gimignano, Pisa and Lunch at a Winery
$82
per adult
98% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
$133
per adult
100% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$21
per adult
80% of travellers recommend
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
$38
per adult
92% of travellers recommend
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
$63
per adult
92% of travellers recommend
Santo Spirito Hotel Deals
Hotel Horto Convento
Viale Ariosto, 13 Florence FI
$115 nightly
The price is $143 total per night from Aug 18 to Aug 19
$143 total
Aug 18 - Aug 19
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
La Torre Del Cestello
Via Borgo San Frediano, 8 Florence FI
$100 nightly
The price is $126 total per night from Aug 12 to Aug 13
$126 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Cathedral of Santa ...
9/10 Wonderful! (287 reviews)
"I had a wonderful stay. The room was clean, spacious and comfortable. The location was convenient and a quick walk to the metro, attractions and many dining options. The room provided many extra amenities such as water, coffee and bathroom slippers. The air conditioning unit in my room was very weak ..."
Reviewed on Aug 4, 2026
UNA Hotels Vittoria Firenze
Via Pisana 59 Florence FI
$81 nightly
The price is $105 total per night from Aug 11 to Aug 12
$105 total
Aug 11 - Aug 12
Total with taxes and fees
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
Foresteria Valdese di Firenze - Casa per Ferie
Via dei Serragli 49 Florence FI
$82 nightly
The price is $104 total per night from Aug 10 to Aug 11
$104 total
Aug 10 - Aug 11
Total with taxes and fees
Stay at this guesthouse in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (233 reviews)
"Conveniently located. Monica was super helpful. I would definitely stay there again."
Reviewed on Jul 20, 2026
Palazzo Mannaioni Suites
Via Maffia 9 - 17r Florence FI
$179 nightly
The price is $213 total per night from Aug 12 to Aug 13
$213 total
Aug 12 - Aug 13
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and premium bedding. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,152 reviews)
"We loved this apartment! The staff were friendly and helpful, suggesting places to eat and ordering taxis to the train station. The apartment was perfect for what we wanted - would highly recommend and would absolutely stay here again"
Reviewed on Aug 5, 2026
Hostel Santa Monaca
Via Santa Monaca 6 Florence FI
Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Piazza della ...
7.8/10 Good! (64 reviews)
"No"
Reviewed on Jul 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santo Spirito
Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Piazza del Duomo are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Cathedral of Santa Maria del Fiore and Piazza del Duomo are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
Santa Croce
Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.
Santo Spirito
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