Find hotels near Santo Spirito Hospital, Rome from $111

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Compare 14,937 hotels close to Santo Spirito Hospital with room rates, reviews, and availability. Most hotels are fully refundable.

San Pietro Boutique Rooms

Prati, 0.3 mi from Santo Spirito Hospital
10.0 out of 10, Exceptional, (912)
"Perfect location, spacious room, very clean, lovely welcome and service! Absolutely recommend!"
United Kingdom
Eric
$141 nightly
The price is $166
Jan 7 - Jan 8, 2026
Total with taxes and fees
San Pietro Boutique Rooms

Hotel De' Ricci - Small Luxury Hotels of The World

4.0 star property
Regola, 0.4 mi from Santo Spirito Hospital
10.0 out of 10, Exceptional, (115)
"Beautiful hotel in an excellent location. Cocktails at the Charade bar were amazing- we were amazed at the knowledge and creativeness of the staff! The recommendation for dinner at Pierluigi was outstanding- attention to detail, service, and walkable location away from it all- this hotel is a hidden gem! "
United States
Christen
$386 nightly
The price is $442
Dec 10 - Dec 11
Total with taxes and fees
Hotel De' Ricci - Small Luxury Hotels of The World

Passpartout Boutique Palace

0.3 mi from Santo Spirito Hospital
9.8 out of 10, Exceptional, (245)
"Excellent location, great dining options nearby, modern boutique hotel."
Canada
Matthew
$125 nightly
The price is $154
Dec 14 - Dec 15
Total with taxes and fees
Passpartout Boutique Palace

Corso Vittorio 308

0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (63)
"The staff and property made for a 5 star stay."
United States
Brady
Corso Vittorio 308

Charme 308

0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (95)
"Great location! The room was spotless. We loved everything about this place."
United States
Heather
$132 nightly
The price is $162
Dec 15 - Dec 16
Total with taxes and fees
Charme 308

Navona Street Hotel

3.0 star property
0.2 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (268)
"Staff was very friendly and helpful. "
United States
Eli M
$126 nightly
The price is $153
Dec 14 - Dec 15
Total with taxes and fees
Navona Street Hotel

Hotel Sant' Anna

3.0 star property
0.3 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (322)
"Wonderful location, very helpful service and staff!"
United States
Stephen
$198 nightly
The price is $232
Dec 18 - Dec 19
Total with taxes and fees
Hotel Sant' Anna

Le Suite Del Barone

0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (416)
"We enjoyed our stay very much. "
Germany
Ulrike
$122 nightly
The price is $150
Dec 18 - Dec 19
Total with taxes and fees
Le Suite Del Barone

Passepartout

Parione, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (283)
"Kind and helpful and in a great place. It was in the best spot to see every thing I wanted. Perfect for walking to grocery and shopping and restaurants "
United States
Catriona
$105 nightly
The price is $128
Jan 7 - Jan 8, 2026
Total with taxes and fees
Passepartout

Vatican Jubilee

Prati, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (55)
"Great place!"
United States
Hugo
$91 nightly
The price is $115
Jan 7 - Jan 8, 2026
Total with taxes and fees
Vatican Jubilee

Cassiodoro 19

Prati, 0.4 mi from Santo Spirito Hospital
9.6 out of 10, Exceptional, (523)
"Excelente trato"
Mexico
Eddy Alejandro
$130 nightly
The price is $158
Dec 14 - Dec 15
Total with taxes and fees
Cassiodoro 19

Palazzo Medusa

0.2 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (285)
"Great location, friendly and helpful staff, spotless room - I highly recommend!!!"
United Kingdom
James
$105 nightly
The price is $128
Dec 16 - Dec 17
Total with taxes and fees
Palazzo Medusa

B&B Rome River Inn

0.2 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (505)
"Staff very helpful Good location Enjoyed stay"
Australia
Richard
$121 nightly
The price is $147
Jan 7 - Jan 8, 2026
Total with taxes and fees
B&B Rome River Inn

All’Orologio

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (167)
"Very happy with my choice… staff were excellent communicators before and during my stay, loved the location. "
Canada
Andrew
$126 nightly
The price is $153
Dec 14 - Dec 15
Total with taxes and fees
All’Orologio

The Pope's Window

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (410)
"Good location and spacious room"
Canada
Qing
$88 nightly
The price is $111
Dec 10 - Dec 11
Total with taxes and fees
The Pope's Window

Residenza Adriana

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (192)
"It was very nice!"
United States
Benjamin
$100 nightly
The price is $124
Jan 7 - Jan 8, 2026
Total with taxes and fees
Residenza Adriana

HiSuiteROME

0.3 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (395)
"Clean room, amenities, and the staff were Excellent!! "
United States
Diana
$169 nightly
The price is $200
Dec 11 - Dec 12
Total with taxes and fees
HiSuiteROME

Now Apartments

0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (58)
"Such a great apartment in a very cool spot, access to lots of restaurants and shopping. Really loved our stay and would revisit. "
Australia
Renee
$214 nightly
The price is $250
Dec 16 - Dec 17
Total with taxes and fees
Now Apartments

Domus Terenzio

Prati, 0.4 mi from Santo Spirito Hospital
9.4 out of 10, Exceptional, (53)
"Breakfast was fabulous."
United States
Mary
Domus Terenzio

Villa Agrippina Gran Meliá - The Leading Hotels of the World

5.0 star property
Trastevere, 0.1 mi from Santo Spirito Hospital
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
$468 nightly
The price is $538
Jan 8 - Jan 9, 2026
Total with taxes and fees
Villa Agrippina Gran Meliá - The Leading Hotels of the World
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Spirito Hospital Hotel Reviews

Hotels near other Santo Spirito Hospital attractions

Frequently asked questions

What are the top-rated hotels near Santo Spirito Hospital?
Discovering the ideal top-rated hotels near Santo Spirito Hospital can enhance your visit to Rome, Lazio, Italy, offering both comfort and convenience.

Hotel Artemide

Hotel Artemide boasts an impressive review rating of 9.8 and is a 4-star gem situated only 1.9 miles from Santo Spirito Hospital. This hotel features an exquisite rooftop terrace, perfect for relaxing after a day of exploration. Guests can enjoy the on-site spa with treatments like deep tissue massage and reflexology, along with an alfresco restaurant. The combination of premium bedding and 24-hour fitness facilities ensures a comfortable and invigorating stay.

iQ Hotel Roma

iQ Hotel Roma, rated 9.8 by travelers, is a charming 4-star hotel located just 2.3 miles from Santo Spirito Hospital. This hotel features a delightful rooftop garden where travelers can unwind and enjoy the views. With amenities like an alfresco restaurant and free cribs, it caters to diverse needs. The convenient on-site parking and daily housekeeping contribute to a straightforward experience for travelers.
What hotels are within walking distance to Santo Spirito Hospital?
Discover excellent accommodation options just a short stroll from Santo Spirito Hospital, offering top-rated amenities and comfort for every traveler.

Hotel Adriano Rooftop

Hotel Adriano Rooftop is a 4-star gem located a mere 16 minutes on foot from Santo Spirito Hospital, with an impressive review rating of 9.6. This stylish hotel features a beautiful furnished balcony, perfect for enjoying the vibrant views of the historical district. Guests can indulge in a complimentary buffet breakfast daily, and the convenience of a 24-hour airport shuttle enhances the travel experience. With daily housekeeping and nearby fitness facilities, it's an inviting retreat for those visiting the area.

Hotel Isa

Just 13 minutes walking from Santo Spirito Hospital, Hotel Isa is a delightful boutique hotel rated 9.4 by travelers. The hotel features a stunning rooftop garden terrace, offering a peaceful escape amidst the city's hustle and bustle. Guests appreciate the complimentary toiletries and daily housekeeping, ensuring a comfortable stay. The 24-hour airport shuttle service and concierge support add to the convenience for travelers on the go.

Hotel Abruzzi

A charming 3-star option, Hotel Abruzzi is located 18 minutes from Santo Spirito Hospital and has earned a solid review rating of 9.4. This hotel offers travelers the luxury of private hot tubs in select suites, providing a relaxing space after a day exploring Rome. Daily breakfast is complimentary, and thoughtful amenities like free toiletries and climate control ensure a comfortable stay. With its historical district location and concierge services, it's a great choice for travelers seeking a warm and welcoming atmosphere.
How much is a hotel near Santo Spirito Hospital?
Staying near Santo Spirito Hospital is a treat, with plenty of hotels from $111 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.
What are the most popular family-friendly hotels near Santo Spirito Hospital?
For families seeking top-rated accommodations near Santo Spirito Hospital, Rome offers a selection of family-friendly hotels that ensure a comfortable stay for all ages.

Rome Cavalieri, A Waldorf Astoria Hotel

Located only 2.5 miles from Santo Spirito Hospital, Rome Cavalieri, A Waldorf Astoria Hotel is a luxurious 5-star hotel with a great traveler rating score of 9.2. This family-friendly hotel offers an array of amenities, including a children's pool, free cribs, and an onsite babysitting service. Guests will also enjoy access to a spa, a rooftop terrace, and a variety of dining options.

Hotel Villa Pamphili Roma

Hotel Villa Pamphili Roma is a welcoming 4-star hotel situated 3.5 miles from Santo Spirito Hospital, with an excellent review rating of 9.0. This family-friendly hotel provides free cribs and babysitting services for parents' peace of mind, along with a private garden for relaxation. Guests can also indulge in a buffet breakfast, enjoy the pool, and take advantage of the onsite spa services.
Are there any 5-star hotels near Santo Spirito Hospital?
Discovering the perfect 5-star hotels near Santo Spirito Hospital can elevate your stay in Rome with top-rated accommodations and exceptional amenities.

Rome Cavalieri, A Waldorf Astoria Hotel

Rome Cavalieri, A Waldorf Astoria Hotel, situated 2.5 miles from Santo Spirito Hospital, is another exceptional 5-star option with a review rating of 9.2. This hotel stands out with its lush gardens and expansive wellness facilities including a full-service spa and hydrotherapy treatments. Guests can indulge in gourmet dining, relax by the multiple pools, and enjoy rooftop terraces with breathtaking views. The blend of luxury and accessibility makes this hotel a top choice for visitors seeking an indulgent experience.

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal is a distinguished 5-star hotel located merely 2.5 miles from Santo Spirito Hospital, rated 9.4 by travelers. This elegant hotel features a stunning terrace for alfresco dining and a hot tub for ultimate relaxation. Guests can enjoy luxurious amenities like Egyptian cotton sheets, designer toiletries, and in-room massage services. The historical charm of the area complements the boutique experience, making it a desirable choice for those visiting Rome.
Which hotels near Santo Spirito Hospital offer the best views?
For travelers seeking hotels with stunning views near Santo Spirito Hospital, Rome offers some exceptional choices.

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Parco dei Principi Grand Hotel & SPA is a luxurious 5-star hotel situated only 3.3 miles from Santo Spirito Hospital, a travelers' rating of 9.0. Guests can revel in views of the lush gardens from the terrace and enjoy an array of top amenities, including a full-service spa, indoor and outdoor pools, and a restaurant offering garden views. The hotel promises a lavish experience with exceptional service and relaxation.

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá is a prestigious 5-star hotel located just 1.3 miles from Santo Spirito Hospital, with an impressive review rating of 9.2. This hotel features a scenic terrace perfect for enjoying panoramic views and a luxurious outdoor pool. Guests can indulge in spa treatments, and the hotel's close nearby historical sites adds to its allure. With its elegant design and high-end amenities, this hotel offers a remarkable stay.

Hotel Villa Pamphili Roma

Hotel Villa Pamphili Roma is a 4-star gem located just 3.5 miles from Santo Spirito Hospital, rated by travelers at an impressive 9.0. This hotel features a rooftop terrace where travelers can enjoy breathtaking views of the surrounding gardens. With amenities such as a full-service spa, indoor and outdoor pools, and a garden-view restaurant, travelers can unwind and indulge in luxury while taking in the beauty of Rome.
What are the best affordable hotels near Santo Spirito Hospital?
For travelers seeking affordable stays near Santo Spirito Hospital, these top-rated hotels provide comfort and convenience without breaking the bank.

Hotel Smeraldo

Located a short 17-minute walk from Santo Spirito Hospital, Hotel Smeraldo boasts a stellar review rating of 9.4 and a 3-star status. This family-friendly hotel provides travelers with a complimentary buffet breakfast and free WiFi. Enjoy the convenience of in-room kitchenettes and the delightful rooftop terrace, perfect for unwinding after a day of exploring.

Hotel Golden

Hotel Golden is a delightful option located 2.7 miles from Santo Spirito Hospital, holding a review rating of 9.4. While it offers essential amenities like free WiFi and toiletries, its charm lies in its onsite art gallery and romantic atmosphere. Guests appreciate the nearby shopping centers and the historical district, making it a great base for both relaxation and exploration.

Hotel Abruzzi

Hotel Abruzzi, rated by travelers at 9.4, is a charming 3-star hotel situated just 1.6 miles from Santo Spirito Hospital. Ideal for families and budget-conscious travelers, it offers amenities such as free breakfast and WiFi, along with 24-hour airport shuttle service. Guests can relax in the hot tub or enjoy the spacious suites featuring premium bedding and air conditioning.
What are the best boutique hotels near Santo Spirito Hospital?
For travelers seeking top-rated boutique hotels near Santo Spirito Hospital, Rome offers a selection of charming stays that blend comfort and style.

Hotel Barocco

Hotel Barocco, a delightful 4-star boutique hotel, is located just 2.3 miles from Santo Spirito Hospital and boasts an impressive review rating of 9.6. This family-friendly hotel features amenities like babysitting services and air conditioning for a comfortable stay. Guests can also enjoy traditional hotel design, daily housekeeping, and access to a concierge for all their needs.

Hotel Isa

Situated only a 13-minute walk from Santo Spirito Hospital, Hotel Isa is a boutique haven rated 9.4 by travelers. This 4-star hotel offers a rooftop terrace and babysitting services, making it ideal for families. Guests can relax in the garden or take advantage of the complimentary toiletries and daily housekeeping for a pleasant experience.

Hotel Splendide Royal - The Leading Hotels of the World

Just 2.5 miles from Santo Spirito Hospital, the 5-star Hotel Splendide Royal has an outstanding traveler rating of 9.4. Guests can unwind on the terrace or indulge in in-room massages, ensuring a memorable stay.
Are there any hotels with pools close to Santo Spirito Hospital?
If you're seeking a luxurious stay with pools close to Santo Spirito Hospital, Rome offers some excellent options for travelers looking to unwind.

Rome Cavalieri, A Waldorf Astoria Hotel

Rome Cavalieri, A Waldorf Astoria Hotel is a 5-star luxury haven located just 2.5 miles from Santo Spirito Hospital, with an impressive travelers' rating of 9.2. Guests can enjoy a stunning outdoor pool complete with sun loungers, cabanas, and a poolside bar, perfect for relaxation. Additional amenities include a full-service spa, fitness facilities, and gourmet dining, making it an ideal choice for those seeking comfort and elegance.

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Parco dei Principi Grand Hotel & SPA is a luxurious 5-star hotel located 3.3 miles from Santo Spirito Hospital, with a strong travelers' rating of 9.0. The hotel offers a serene indoor pool along with sun loungers and a refreshing poolside bar. With a full-service spa, gourmet dining options, and comprehensive fitness facilities, this hotel caters to travelers looking for relaxation and indulgence.

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá is a 5-star retreat situated only 1.3 miles from Santo Spirito Hospital, with a stellar review rating of 9.2. The hotel features an inviting outdoor pool with sun loungers and a poolside bar, ideal for enjoying sunny days. Guests will also appreciate luxurious amenities including a full-service spa, 24-hour fitness facilities, and exquisite dining options, ensuring a memorable stay.
What are the best pet-friendly hotels near Santo Spirito Hospital?
For those seeking pet-friendly accommodations near Santo Spirito Hospital, there are several excellent options that cater to both you and your furry friends while ensuring a comfortable stay.

Trilussa Palace Wellness & Spa

Trilussa Palace Wellness & Spa is a luxurious 4-star hotel situated 2.8 miles from Santo Spirito Hospital. Rated 8.6 by travelers, this hotel allows pets and provides thoughtful amenities such as food and water bowls for your furry companions. Guests can indulge in the on-site spa facilities, including an indoor pool and steam room. The hotel also features covered parking and a romantic atmosphere, making it an ideal retreat for pet owners looking for relaxation.

Hotel Pacific Roma

Hotel Pacific Roma, a 3-star hotel located just 1.5 miles from Santo Spirito Hospital, welcomes pets with open arms. With a review rating of 9.0, this hotel provides essential pet-friendly amenities including food and water bowls, litter boxes, and in-room pet permissions. Guests can enjoy complimentary buffet breakfast, 24-hour airport shuttle service, and spacious rooms with premium bedding. Perfect for travelers with pets, this hotel ensures a relaxing stay for everyone.

Albani Hotel Roma

Albani Hotel Roma, a charming 4-star hotel located 3.3 miles from Santo Spirito Hospital, boasts a solid review rating of 8.4. This pet-friendly hotel allows pets in rooms and provides food and water bowls for their comfort. Guests can take advantage of the historical district location, enjoy daily housekeeping, and relax on the terrace. With covered parking and babysitting services available, this hotel caters well to families traveling with pets.
Can I book a fully refundable hotel close to Santo Spirito Hospital?
Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Santo Spirito Hospital", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.
Can I find Expedia discounts for hotels near Santo Spirito Hospital?
To look for discounts on hotels near Santo Spirito Hospital, join One Key™—our free travel rewards program. One Key members always get our best prices and earn OneKeyCash™* on eligible bookings for every dollar spent. Another way to save is by bundling your hotel and flights together on Expedia.

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