Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Syracuse Independent Hotels

See all 797 Hotels in Syracuse
Royal Maniace Hotel

Royal Maniace Hotel

Lungomare di Ortigia,13, Syracuse
    4.0 out of 5.0
     
     
    4.4 out of 5 (313 reviews)
    Beautiful room with superb views over the water Great hotel with lovely staff. The room surpasses expectations with the balcony overlooking the wat … - 

    Royal Maniace Hotel$103

    Royal Maniace Hotel$103
    Maison Ortigia

    Maison Ortigia

    Piazza San Giuseppe, 25, Syracuse
       
       
      4.3 out of 5 (11 reviews)
      Great b and b! Good location. Nice breakfast. Friendly staff. We had a perfect stay in the two bedroom apartment f … - 

      Maison Ortigia$72

      Maison Ortigia$72
      Grande Albergo Alfeo

      Grande Albergo Alfeo

      Via Nino Bixio 5, Syracuse
        4.0 out of 5.0
         
         
        4.3 out of 5 (328 reviews)
        A 'grand' hotel very near historic Ortegia. Staff were friendly and helpful. The hotel surpassed our expectations for one so reasonably priced. … - 

        Grande Albergo Alfeo$95

        Grande Albergo Alfeo$95
        Grand Hotel Villa Politi

        Grand Hotel Villa Politi

        Via Maria Politi Laudien 2, Syracuse
          4.0 out of 5.0
           
           
          4.2 out of 5 (490 reviews)
          Well located. Free parking was nice and good appetizers with drinks. - 

          Grand Hotel Villa Politi$102

          Grand Hotel Villa Politi$102
          Domus Mariae Benessere

          Domus Mariae Benessere

          Via Vittorio Veneto, 89, Syracuse
            3.0 out of 5.0
             
             
            4.4 out of 5 (113 reviews)
            Nice hotel in interesting location. Splendid hotel for adults- not suitable for children. Old fashioned interior, nice and clean. Large … - 

            Domus Mariae Benessere$74

            Domus Mariae Benessere$74
            Domus Mariae Albergo

            Domus Mariae Albergo

            Via Vittorio Veneto 76, Syracuse
              3.0 out of 5.0
               
               
              4.3 out of 5 (123 reviews)
              Fabulous hotel in a great location We were greeted with warmth and friendliness by Cinzia, who was incredibly helpful. All the staff w … - 

              Domus Mariae Albergo$93

              Domus Mariae Albergo$93
              Hotel Flora

              Hotel Flora

              Vico Brindisi, 3, Noto
                3.0 out of 5.0
                 
                 
                4.2 out of 5 (78 reviews)
                Great location. Friendly staff Great location near centre. Very friendly staff. Good parking once you find it down a tiny street t … - 

                Hotel Flora$83

                Hotel Flora$83
                Grand Hotel Ortigia Siracusa

                Grand Hotel Ortigia Siracusa

                Viale Mazzini, 12, Syracuse
                  5.0 out of 5.0
                   
                   
                  4.4 out of 5 (338 reviews)
                  probably best location on ortigia island - good access and parking. walk to all other activities on … - 

                  Grand Hotel Ortigia Siracusa$230

                  Grand Hotel Ortigia Siracusa$230
                  L'Approdo delle Sirene

                  L'Approdo delle Sirene

                  Riva Giuseppe Garibaldi 15, Syracuse
                    3.0 out of 5.0
                     
                     
                    4.5 out of 5 (100 reviews)
                    small hotel near marina Quirky hotel with great views from the balcony. Very good breakfast. Compared favourably with 5 sta … - 

                    L'Approdo delle Sirene$107

                    L'Approdo delle Sirene$107
                    Aretusa Vacanze B&B

                    Aretusa Vacanze B&B

                    Vicolo Zuccalà 1, Syracuse
                      1.0 out of 5.0
                       
                       
                      4.6 out of 5 (137 reviews)
                      Wonderful B&B This was a great place to stay in the heart of Ortigia, Syracuse. We felt welcomed on arrival and w … - 

                      Aretusa Vacanze B&B$79

                      Aretusa Vacanze B&B$79
                      Resort Sant'Agostino

                      Resort Sant'Agostino

                      Traversa Case Bianche, Syracuse
                        4.0 out of 5.0
                         
                         
                        4.6 out of 5 (50 reviews)
                        Fabulous base for exploring the Siracusa Region. The resort consists of several farm buildings converted into high quality well equipped appartments … - 

                        Resort Sant'Agostino$70

                        Resort Sant'Agostino$70
                        Hotel Porta Reale

                        Hotel Porta Reale

                        Corso Vittorio Emanuele 161, Noto
                          4.0 out of 5.0
                           
                           
                          4.9 out of 5 (15 reviews)
                          Excellent stay Perfect location, fantastic staff and lovely rooms. Will definitely come here again! - 

                          Hotel Porta Reale$121

                          Hotel Porta Reale$121
                          Alla Giudecca

                          Alla Giudecca

                          Via Alagona 52, Ortigia, Syracuse
                            3.0 out of 5.0
                             
                             
                            4.1 out of 5 (119 reviews)
                            Stylish hotel in perfect location This hotel in ideal for a stay of a few days in Ortigia. It is a clever modernisation of an ancient … - 

                            Alla Giudecca$121

                            Alla Giudecca$121
                            B&B La Via della Giudecca

                            B&B La Via della Giudecca

                            Piazza San Filippo, Syracuse
                              3.0 out of 5.0
                               
                               
                              4.7 out of 5 (93 reviews)
                              Great location and spacious room Lovely hotel, great Air-con, location was central in Ortigia and the staff were all very friendly a … - 
                              B&B Nostos

                              B&B Nostos

                              Corso Umberto I, 66, Syracuse
                                3.0 out of 5.0
                                 
                                 
                                4.7 out of 5 (50 reviews)
                                Simple and modern Great location, walking distance to everything. Room was modern and clean. Breakfast was served at … - 

                                B&B Nostos$99

                                B&B Nostos$99
                                Giuggiulena Villa

                                Giuggiulena Villa

                                Via Pitagora da Reggio 35, Syracuse
                                  3.0 out of 5.0
                                   
                                   
                                  4.8 out of 5 (40 reviews)
                                  A Taste of Paradise This beats most 5 star resorts as far as experiences are concerned. Sabrina and Claudia made us fee … - 

                                  Giuggiulena Villa$141

                                  Giuggiulena Villa$141
                                  Hotel Siracusa

                                  Hotel Siracusa

                                  cda Spalla,, Syracuse
                                    4.0 out of 5.0
                                     
                                     
                                    4.0 out of 5 (50 reviews)

                                    Hotel Siracusa$85

                                    Hotel Siracusa$85
                                    Il Podere Hotel Restaurant

                                    Il Podere Hotel Restaurant

                                    Traversa Torre Landolina 11, Syracuse
                                      4.0 out of 5.0
                                       
                                       
                                      4.2 out of 5 (95 reviews)
                                      Lovely hotel in countryside Thank goodness for the GPS, as without it, we would never have found Il Podere, which is in a very … - 

                                      Il Podere Hotel Restaurant$67

                                      Il Podere Hotel Restaurant$67
                                      Morfeo Val di Noto

                                      Morfeo Val di Noto

                                      Via Procida 108, Avola
                                         
                                         
                                        4.8 out of 5 (6 reviews)

                                        Morfeo Val di Noto$61

                                        Morfeo Val di Noto$61
                                        Hotel Posta

                                        Hotel Posta

                                        Via Trieste 33, Syracuse
                                          3.0 out of 5.0
                                           
                                           
                                          4.0 out of 5 (217 reviews)
                                          Good Location Very clean room, adequate accommodations in an area with good parking. Easy walk to everything. Goo … - 

                                          Hotel Posta$87

                                          Hotel Posta$87
                                          Map

                                          Recently booked Syracuse hotels

                                          Algila' Ortigia Charme Hotel
                                          4.0 out of 5.0
                                          Last booking: 37 minutes ago
                                          Mercure Siracusa Prometeo
                                          4.0 out of 5.0
                                          Last booking: 43 hours ago

                                          Independent Syracuse Hotel Guide

                                          Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Syracuse, Sicily. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Syracuse hotels guarantees an unparalleled level of comfort and quality.

                                          You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Syracuse Independent locations may even offer extra little benefits and discounts for frequent travelers.