Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Winston - Salem Business Hotels

See all 228 Hotels in Winston - Salem
Hawthorne Inn and Conference Center

Hawthorne Inn and Conference Center

420 High St, Winston-Salem
3.5 out of 5.0
4.3 out of 5 (609 reviews)
Nice hotel, centrally located. The room was clean and comfortable. Staff was Curtis and professional. I would return
  Dec 4, 2017

$105

$105
Best Western Plus Hanes Mall Hotel

Best Western Plus Hanes Mall Hotel

3330 Silas Creek Pkwy, Winston-Salem
3.0 out of 5.0
4.1 out of 5 (1,184 reviews)
ConvenientExceptionally helpful staff. Friendly breakfast staff.
  Jan 16, 2018

$76

$76
Fairfield Inn & Suites by Marriott Winston-Salem Downtown

Fairfield Inn & Suites by Marriott Winston-Salem Downtown

125 S Main St, Winston-Salem
3.0 out of 5.0
4.1 out of 5 (534 reviews)
Nice, close to Winston Salem State UniversityStaff was very friendly, room was clean and comfortable. Carpet in hallway needed some cleaning and there was no fan in the bathroom. Other than that the stay was very nice. I would stay again.
  Nov 12, 2017

$88

$88
Village Inn Hotel & Event Center

Village Inn Hotel & Event Center

6205 Ramada Dr, Clemmons
3.5 out of 5.0
3.9 out of 5 (368 reviews)
Nice hotel, quiet and friendly.We have stayed at this hotel several times the past few years. This is convenient to the car dealer we go to for service for our cars. There are several restaurants near the hotel and sometimes we eat at the hotel as it is usually a quiet place and close to the room.
  Dec 29, 2017

$89

$89
Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

Fairfield Inn & Suites by Marriott Winston-Salem Hanes Mall

1680 Westbrook Plaza Dr, Winston-Salem
3.0 out of 5.0
4.5 out of 5 (267 reviews)
Super Friendly Management and StaffThis was our first time staying at this hotel and we were very pleased with everything. It is very convenient to restaurants and stores. The room was very clean which is always important to us. We had our fur baby with us, the staff was very friendly to him. The breakfast each morning was superb! ...
  Jan 3, 2018

$89

$89
Holiday Inn Exp Winston Salem

Holiday Inn Exp Winston Salem

2520 Peters Creek Pkwy, Winston-Salem
3.5 out of 5.0
4.2 out of 5 (185 reviews)
Centrally locatedWe stayed 2 nights right after Christmas. The Inn sets right in the middle of everything. Shopping, dinning, and my two children who live on the outskirts of Winston-Salem. We had a very good visit thanks to you all.
  Dec 29, 2017

$93

$93
Winston-Salem Hotel and Spa

Winston-Salem Hotel and Spa

3050 University Pkwy, Winston-Salem
3.0 out of 5.0
3.2 out of 5 (526 reviews)
Under renovationNice place but under renovation, so noisy. Hot a cheap rate for inconvenience and rooms are nice. This place will be great when finished.
  Jan 9, 2018

$80

$80
La Quinta Inn & Suites Winston - Salem

La Quinta Inn & Suites Winston - Salem

2020 Griffith Rd, Winston-Salem
3.0 out of 5.0
4.0 out of 5 (758 reviews)
Close to everythingEnjoyed. Will stay again. Could use updating in room design. Not far from Wake. Affordable. They had a pipe burst in the lobby, but they were very accommodating. Room was very clean. I loved the personal note from housekeeping. The traffic in the area was very bad though. Turning from the main Mall ...
  Jan 14, 2018

$75

$75
The Historic Brookstown Inn

The Historic Brookstown Inn

200 Brookstown Ave, Winston-Salem
3.5 out of 5.0
4.4 out of 5 (1,346 reviews)
My husband made a great choice! We’re on a college visit and wanted a unique experience where we stayed. He found Brookstown Inn and we have enjoyed the space and the staff. We’ll stay again if UNCSA is the place for our son!
  Jan 20, 2018

$115

$115
Microtel Inn by Wyndham Winston Salem

Microtel Inn by Wyndham Winston Salem

100 Capital Lodging Ct, Winston-Salem
2.5 out of 5.0
3.9 out of 5 (1,573 reviews)
just what we needed.clean, quiet, convenient, safe economical, waffles
  Jan 16, 2018

$59

$59
DoubleTree by Hilton Hotel Winston Salem - University

DoubleTree by Hilton Hotel Winston Salem - University

5790 University Pkwy, Winston-Salem
3.5 out of 5.0
4.1 out of 5 (351 reviews)
Very friendly and accommodating staff. Hotel is very clean and has all the amenities needed for families or business travelers. Lastly, the hotel is in a great and safe location for Winston Salem and is easily accessible from the major roads and highway.
  Jan 3, 2018

$88

$88
Holiday Inn Express Kernersville

Holiday Inn Express Kernersville

1570 Highway 66 S, Kernersville
3.0 out of 5.0
4.2 out of 5 (158 reviews)
Too near to the road so it is noisy Food is ok Decent value for the cost
  Jan 18, 2017

$113

$113
Kimpton Cardinal Hotel

Kimpton Cardinal Hotel

51 East 4th St, Winston-Salem
5.0 out of 5.0
4.6 out of 5 (170 reviews)
Very comfortable and clean. Love that they allow dogs and are so dog friendly!
  Dec 19, 2017

$144

$144
Embassy Suites Hotel Winston-Salem

Embassy Suites Hotel Winston-Salem

460 N Cherry St, Winston-Salem
4.0 out of 5.0
4.2 out of 5 (278 reviews)
Stayed for NYE to enjoy Area Restaurant and Attend Party. From the Minute we Checked in until we had out cooked to Order Breakfast.... The staff and facilities were great. definitely will go back.
  Jan 2, 2018

$116

$116
Quality Inn & Suites Hanes Mall

Quality Inn & Suites Hanes Mall

2008 S Hawthorne Rd, Winston-Salem
3.0 out of 5.0
3.5 out of 5 (700 reviews)
Good Hotel For The PriceThe room was clean and comfortable. The location is close to the highway. The staff was polite and helpful at any hour. The WiFi password changes daily which is kind of annoying.
  Dec 4, 2017

$59

$59
Sleep Inn

Sleep Inn

1406 Heartland Dr, Kernersville
3.0 out of 5.0
4.1 out of 5 (148 reviews)
We had a very pleasant stay for a Family Weekend event in the area. The hotel was able to accommodate our request to have 2 rooms next to each other. The beds were comfortable and we slept well. The staff and other guests were nice and welcoming. The complimentary breakfast was filling and delicious ...
  Nov 7, 2017

$75

$75
Hampton Inn Bermuda Run/Advance

Hampton Inn Bermuda Run/Advance

196 NC Highway 801 N, Advance
3.0 out of 5.0
4.6 out of 5 (299 reviews)
Nice hotel close to highway Mostly friendly, courteous staff USA Today newspaper available at breakfast Stayed in functional non-smoking room with 2 queen beds on first floor
  Dec 27, 2017

$97

$97
Graylyn Estate

Graylyn Estate

1900 Reynolda Rd., Winston-Salem
5.0 out of 5.0
4.6 out of 5 (68 reviews)
Bring a Sweater!The Inn is very beautiful, wonderful setting, convenient to sightseeing in the area of Wake Forest, Tanglewood, however the original windows have not been replaced...very drafty. The Inn has several Stone Fireplaces through out the common areas that are very cozy....the staff was very helpful, the ...
  Dec 27, 2017

$189

$189
Comfort Suites Hanes Mall

Comfort Suites Hanes Mall

200 Capitol Lodging Ct, Winston-Salem
3.0 out of 5.0
4.4 out of 5 (483 reviews)
Quick tripWe were only there one night. It was great. The only bad thing was renovations going on in the lobby. It was no bother and breakfast was served in the conference room. They also stopped working at 6. So no disruption.
  Dec 18, 2017

$74

$74
Days Inn Mocksville

Days Inn Mocksville

1500 Yadkinville Rd, Mocksville
3.0 out of 5.0
3.3 out of 5 (59 reviews)
It is was nice and fairly quiet. I would have liked for the curtain to block out a little more of the light coming in the room, but other than that it was good.
  Dec 4, 2017

$55

$55
Map

Recently booked Business Hotels in Winston - Salem

Embassy Suites Hotel Winston-Salem
4.0 out of 5.0
Last booking: 43 minutes ago
The Historic Brookstown Inn
3.5 out of 5.0
Last booking: 2 hours ago
Graylyn Estate
5.0 out of 5.0
Last booking: 2 hours ago
Best Western Plus Hanes Mall Hotel
3.0 out of 5.0
Last booking: 2 hours ago
Springhill Suites by Marriott Winston-Salem Hanes Mall
3.5 out of 5.0
Last booking: 6 hours ago
Holiday Inn Exp Winston Salem
3.5 out of 5.0
Last booking: 7 hours ago
Residence Inn by Marriott Winston-Salem University Area
3.5 out of 5.0
Last booking: 7 hours ago
Quality Inn
3.0 out of 5.0
Last booking: 10 hours ago
Fairfield Inn & Suites by Marriott Winston-Salem Downtown
3.0 out of 5.0
Last booking: 10 hours ago

Pocket Guide: Business Hotels in Winston - Salem

Search for hotels in Winston - Salem on Expedia. You can easily find your hotels in Winston - Salem using one of the methods below:

  • View our selection of featured hotels in Winston - Salem
  • Use the map to find hotels in the Winston - Salem neighborhood you prefer
  • Use the filters to see hotels in a specific area of Winston - Salem, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Winston - Salem
  • Enter your travel dates to view the best deals on hotels in Winston - Salem - while they last