A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon 4 Star Hotels

Tonight
Sep 12 - Sep 13
Tomorrow
Sep 13 - Sep 14
Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27

Our top choices for Colon 4-star hotels

A multi-story building with balconies, arched windows, and decorative railings.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A building with a balcony and a street view.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

1. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
$175 nightly
$193 total
Oct 13 - Oct 14
Total with taxes and fees
Central Hotel Panama Casco Viejo
A balcony with a view of a swimming pool, palm trees, and city buildings.
A reception area with marble reception desks and a sign indicating the reception desk.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.

2. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
Althea
$82 nightly
$91 total
Sep 17 - Sep 18
Total with taxes and fees
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A modern spa area with a hot tub, seating, and a city view.
A rooftop lounge with modern seating and a panoramic city view.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
TREVOR
$138 nightly
$138 total
Sep 29 - Sep 30
Total with taxes and fees
Megapolis Hotel Panamá
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

4. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Abeke
$111 nightly
$123 total
Sep 18 - Sep 19
Total with taxes and fees
Waymore Hotel Spa & Casino
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.

5. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
pauline
$278 nightly
$278 total
Oct 1 - Oct 2
Total with taxes and fees
Dreams Playa Bonita Panama - All Inclusive
A buffet with various food items including fruits, juices, and cheeses.
A gym with treadmills, weight machines, and dumbbells.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

6. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Stephen
$101 nightly
$111 total
Oct 9 - Oct 10
Total with taxes and fees
Courtyard by Marriott Panama Metromall
A balcony with wicker chairs and a view of the cityscape.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

7. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
$92 nightly
$101 total
Oct 13 - Oct 14
Total with taxes and fees
Ramada Plaza by Wyndham Panama Punta Pacifica
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

8. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Frances
$110 nightly
$121 total
Sep 26 - Sep 27
Total with taxes and fees
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A spacious lobby with a staircase, seating area, and a bar.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.

9. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
$132 nightly
$145 total
Sep 28 - Sep 29
Total with taxes and fees
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A buffet setup with various dishes and utensils.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

10. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
$169 nightly
$186 total
Oct 10 - Oct 11
Total with taxes and fees
Marriott Panama Hotel
A modern building with a glass facade, a curved structure, and a flat roof.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.

11. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Diana
$101 nightly
$111 total
Sep 28 - Sep 29
Total with taxes and fees
Decapolis Hotel Panama City
A buffet with various food items and a decorative plant.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.
A spa area with a hot tub, candles, and a curved bench.
A gym with treadmills, weight machines, and a red carpet.

12. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Rafael
$176 nightly
$193 total
Sep 19 - Sep 20
Total with taxes and fees
Sheraton Grand Panama
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.
A bar area with a counter, stools, and a seating area with tables and chairs.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

13. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United Kingdom
Samantha
$91 nightly
$100 total
Sep 28 - Sep 29
Total with taxes and fees
Radisson Hotel Panama Canal
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'
A hotel room with a bed, bedside tables, a nightstand, a lamp, a digital clock, a bathroom with a toilet, a sink, and a mirror.

14. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A poolside area with covered seating and palm trees.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.
A modern interior with a large abstract sculpture, a staircase, a sofa with orange cushions, and a patterned rug.
A modern living room with a city view, a flat-screen TV, and a dining area with white chairs and a table.

15. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Charles
$199 nightly
$219 total
Sep 21 - Sep 22
Total with taxes and fees
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.
A hotel room with a bed and a view of a cityscape through sheer curtains.

16. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Philip
$96 nightly
$106 total
Oct 4 - Oct 5
Total with taxes and fees
Novotel Panama City
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A spacious lobby with a tiled floor, large windows, and potted plants.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.
A white building with multiple balconies, large windows, and decorative railings.

17. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
James
$163 nightly
$181 total
Oct 13 - Oct 14
Total with taxes and fees
American Trade Hotel
A restaurant with multiple dining tables, chairs, and a central water feature.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A bar area with multiple seating options, a bar counter, and a fireplace.

18. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
United States
Reid
$280 nightly
$308 total
Oct 9 - Oct 10
Total with taxes and fees
Hotel La Compañía Casco Antiguo
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A rooftop bar with potted plants, seating, and a view of a city skyline.
A bedroom with a large bed, a stone wall, a wooden bench, and a hanging light fixture.
A rooftop terrace with a city skyline view, a pool, and outdoor seating.

19. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Mariana
$54 nightly
$60 total
Oct 13 - Oct 14
Total with taxes and fees
Hotel Casa Panamá
A rooftop pool with lounge chairs and a city skyline view.
A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.
A person seated on a wicker chair with a view of a cityscape through large windows.
A woman sitting on a bed in a hotel room with a city view.

20. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
United States
LINDA
$101 nightly
$111 total
Sep 25 - Sep 26
Total with taxes and fees
Hotel Dann Carlton Marinn Place Panama Financial District
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Colon.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
$138 nightly
$151 total
Sep 27 - Sep 28
Total with taxes and fees
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
$266 nightly
$292 total
Sep 27 - Sep 28
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
Waldorf Astoria Panama
JW Marriott Panama

JW Marriott Panama

Calle Punta Colon, Punta Pacifica Panama City Panama
$255 nightly
$281 total
Oct 3 - Oct 4
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
JW Marriott Panama
Still don't see what you're looking for?
See all properties in Colon.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colorful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

See all hotels in Colon
A coastal archaeological site with ruins and a clear view of the ocean with boats.

Top Colon Hotel Reviews

Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

8/10 Good
"Property needs more maintenance! Staff is super great! They did not change the sheets not even once in the six days we were there."
Javier E 6-night trip
Posted 1 hour ago
Dreams Playa Bonita Panama - All Inclusive
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Loved my stay! The staff was extremely helpful and the amenities were great!"
Daniel 3-night trip
Posted 3 hours ago
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

8/10 Good
"Our neighbors beside us had children that were very very loud, had to complain twice. Also had workers on the floor above us and they were beating and banging also very loud."
Willis 2-night trip
Posted 3 hours ago
Waymore Hotel Spa & Casino
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"The persons that checked me in were so wonderful ! Also the housekeeper !. Perfect experience"
Angel 4-night trip
Posted 1 day ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Find out more about Colon

The preparation of any much-needed vacation gets started with selecting a location. Colon has become a popular choice with travelers because it offers so much. Location is everything, but that accounts for more than the town you are flying into. Now that you have got a feel for the town, it is time you to get to know your new digs.

Accommodations as Stunning as the City

Colon saw its fair share of visitors this past year. Expedia's comment section includes comments that can help you narrow down your pick. The resorts found here aim to make your stay as pleasant as your evenings hanging out in Colon. These hotels strive to make their facilities and grounds welcoming from the minute you step out of your car. You will never need to go far to find a delicious snack, to sustain your workout routine, or for an energizing plunge during your visit with all they offer.

Rooms have been fashioned to keep you as cozy as possible, with amenities like ultra-comfortable bedding, and in-room tea or coffee, and designer bathroom products. So, sit back and unwind. Moreover, if you find that you're need of something more, you can be confident the staff will try their hardest to ensure you stay pleased during your time. These hotels are so lovely that you'll regret the day you have to check-out.

Book a 4-Star Hotel in Colon Today!

Your holiday to Colon should be one that you'll remember for years to come, and booking a 4-star hotel can help make those memories nothing but incredible. With Expedia, you will get affordable rates on first-class accommodations to take your trip to the next level.

Frequently asked questions

What are the best 4-star hotels in Colon?
If you're seeking high-quality comfort and plenty of amenities during your Colon escape, check out Radisson Colon 2,000 Hotel & Casino. This 4-star hotel comes with a steam room and concierge services. Melia Panama Canal also gets great reviews from Expedia travelers. A tennis court and a terrace are among its conveniences.
How much does it cost to stay in a 4-star hotel in Colon?
Expedia can help you quickly find the perfect 4-star hotel for your getaway in Colon. Use our filter tool to fine-tune your search by things like price, conveniences and property star rating and get access to fabulous deals in a few clicks.
  • Search for the lowest price from $151
What's the difference between 5-star and 4-star hotels in Colon?
If you decide to book a stay at a 4-star hotel in Colon, you'll usually find loads of amenities to ensure you're comfortable, such as a restaurant, gym and pool. You can enjoy excellent service and upmarket surroundings. Opt for a 5-star hotel and you'll get a few extra perks — think around-the-clock concierge, on-site spas and opulent turndown services. You're likely to get additional amenities and first-class services at a 5-star stay, but both are awesome options for luxury travelers.

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