Title: Top Independent in Panhandle, TX - Expedia.com [Panhandle Travel Guide](https://expedia.com/Panhandle.dx6354880)[Hotels in Panhandle](https://expedia.com/Panhandle-Hotels.d6354880.Travel-Guide-Hotels)[Vacation Rentals in Panhandle](https://expedia.com/Panhandle-Vacation-Rentals.d6354880.Travel-Guide-VacationRentals)[Flights to Panhandle](https://expedia.com/Cheap-Flights-To-Panhandle.d6354880.Travel-Guide-Flights)[Car Rentals in Panhandle](https://expedia.com/Car-Rentals-In-Panhandle.d6354880.Car-Rental-Guide)[Panhandle Vacation Packages](https://expedia.com/Panhandle.d6354880.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=6354880&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 23 - Mar 24](https://www.expedia.com/Hotel-Search?regionId=6354880&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=6354880&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6354880&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FPanhandle-Hotels-Independent.0-0-d6354880--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FPanhandle-Hotels-Independent.0-0-d6354880--bIndependent.Travel-Guide-Filter-Hotels) ## Top Panhandle Hotel Reviews ![Microtel Inn & Suites By Wyndham Amarillo West](https://images.trvl-media.com/lodging/108000000/107250000/107247300/107247238/a2af94ee_y.jpg) ### Microtel Inn & Suites By Wyndham Amarillo West 8/10 Good "Quiet, clean and safe neighborhood. " [](https://expedia.com/Amarillo-Hotels-Microtel-Inn-Suites-By-Wyndham-Amarillo-West.h107247238.Hotel-Information) ![Baymont by Wyndham Amarillo East](https://images.trvl-media.com/lodging/1000000/10000/9300/9230/d0453ea1_y.jpg) ### Baymont by Wyndham Amarillo East 6/10 Okay "Bathroom no counter space. Bath tub would not drain. Breakfast wasn’t the best. Older hotel" [](https://expedia.com/Amarillo-Hotels-Baymont-By-Wyndham-Amarillo-East.h9230.Hotel-Information) ![Embassy Suites by Hilton Amarillo Downtown](https://images.trvl-media.com/lodging/17000000/16280000/16272200/16272130/a6ba0dcb_y.jpg) ### Embassy Suites by Hilton Amarillo Downtown 10/10 Excellent "The staff was very friendly and the hotel was spotless. " [](https://expedia.com/Amarillo-Hotels-Embassy-Suites-Amarillo-Downtown.h16272130.Hotel-Information) ![The Cactus Cove Inn and Suites](https://images.trvl-media.com/lodging/82000000/81010000/81001800/81001765/027fa857_y.jpg) ### The Cactus Cove Inn and Suites 8/10 Good "The breakfast is not Continental at all! You pay for the eggs sausage bacon biscuits and gravy. Cereal waffles bagels yogurt is out for everyone to have. The rest is extra cost! Don’t mention it to the server that is serving the extra as she will get flat out pissed! Very bad attitude and will attack you for just mentioning that this is supposed to be apart of the continent breakfast! " [](https://expedia.com/Amarillo-Hotels-The-Cactus-Cove-Inn-And-Suites.h81001765.Hotel-Information) ![Comfort Inn & Suites Amarillo West Near Medical Center](https://images.trvl-media.com/lodging/1000000/810000/802200/802113/3f90f0e3_y.jpg) ### Comfort Inn & Suites Amarillo West Near Medical Center 8/10 Good "Good breakfast, polite and helpful staff, clean property " [](https://expedia.com/Amarillo-Hotels-Comfort-Inn-And-Suites-Amarillo.h802113.Hotel-Information) ![Atrea Inn Amarillo](https://images.trvl-media.com/lodging/67000000/66830000/66822400/66822333/427b1807_y.jpg) ### Atrea Inn Amarillo 8/10 Good "Easy parking, nice staff. " [](https://expedia.com/Amarillo-Hotels-Atrea-Inn.h66822333.Hotel-Information) ![Yellow City Studios ](https://images.trvl-media.com/lodging/123000000/122840000/122839400/122839385/b27a5383_y.jpg) ### Yellow City Studios 10/10 Excellent "I liked this place . " [](https://expedia.com/Amarillo-Hotels-Yellow-City-Studios.h122839385.Hotel-Information) ![Drury Inn & Suites Amarillo](https://images.trvl-media.com/lodging/2000000/1530000/1529800/1529725/728bf030_y.jpg) ### Drury Inn & Suites Amarillo 8/10 Good "Front desk ladies were sweet. We got a free upgraded room too!" [](https://expedia.com/Amarillo-Hotels-Drury-Inn-Suites-Amarillo.h1529725.Hotel-Information) ![Spark by Hilton Amarillo Western Plaza](https://images.trvl-media.com/lodging/6000000/5120000/5111100/5111054/3b77c80b_y.jpg) ### Spark by Hilton Amarillo Western Plaza 10/10 Excellent "Loved everything about this place - clean, spacious rooms, comfy beds, well-lit parking, tasty breakfast and very friendly staff - except the single use plastics at breakfast. It is 2026\. Microplastics aside, have we not all seen the floating plastic islands by now? Some hotels have shifted to corn-based or more biodegradable single use flatware. Still, I would stay here again. " [](https://expedia.com/Amarillo-Hotels-Spark-By-Hilton-Amarillo-Western-Plaza.h5111054.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Square House Museum ](https://www.expedia.com/Square-House-Museum-Hotels.0-l553248621532645942-0.Travel-Guide-Filter-Hotels) - [Hotels near VW Slug Bug Ranch ](https://www.expedia.com/VW-Slug-Bug-Ranch-Hotels.0-l553248621533114916-0.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Claude ](https://www.expedia.com/Claude-Hotels-Wyndham-Hotels.0-0-d6351739--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Claude Hotels ](https://www.expedia.com/Claude-Hotels.d6351739.Travel-Guide-Hotels) - [Motels in Claude ](https://www.expedia.com/Claude-Motels.d6351739-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Claude ](https://www.expedia.com/Claude-Cabins.d6351739-aaCabins.Travel-Guide-Accommodation) - [Rv Parks in Claude ](https://www.expedia.com/Claude-RV-Parks.d6351739-aaRVParks.Travel-Guide-Accommodation) - 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