Title: Top Independent in Roxboro, NC - Expedia.com [Roxboro Travel Guide](https://expedia.com/Roxboro.dx6441)[Hotels in Roxboro](https://expedia.com/Roxboro-Hotels.d6441.Travel-Guide-Hotels)[Vacation Rentals in Roxboro](https://expedia.com/Roxboro-Vacation-Rentals.d6441.Travel-Guide-VacationRentals)[Flights to Roxboro](https://expedia.com/Cheap-Flights-To-Roxboro.d6441.Travel-Guide-Flights)[Car Rentals in Roxboro](https://expedia.com/Car-Rentals-In-Roxboro.d6441.Car-Rental-Guide)[Roxboro Vacation Packages](https://expedia.com/Roxboro.d6441.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6441/c5bcd31f-a61c-4bd7-95ed-fe7e89902e09.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6441/c5bcd31f-a61c-4bd7-95ed-fe7e89902e09.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=6441&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=6441&startDate=2026-04-01&endDate=2026-04-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6441&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6441&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FRoxboro-Hotels-Independent.0-0-d6441--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FRoxboro-Hotels-Independent.0-0-d6441--bIndependent.Travel-Guide-Filter-Hotels) ## Top Roxboro Hotel Reviews ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 8/10 Good "Yes" [](https://expedia.com/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Courtyard Durham Near Duke University/Downtown](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009_y.jpg) ### Courtyard Durham Near Duke University/Downtown 10/10 Excellent "Location " [](https://expedia.com/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Mayo Lake Lower Unit Highend, Clean, Updated](https://images.trvl-media.com/lodging/46000000/45780000/45771400/45771334/0bfbb286_y.jpg) ### Mayo Lake Lower Unit Highend, Clean, Updated 10/10 Excellent "The place was super cute, clean, and exactly like the pictures. " [](https://expedia.com/Roxboro-Hotels-Mayo-Lake-Lower-Unit-Highend.h45771334.Hotel-Information) ![City Express by Marriott Danville](https://images.trvl-media.com/lodging/2000000/1140000/1138200/1138194/19ca7027_y.jpg) ### City Express by Marriott Danville 10/10 Excellent "Excellent " [](https://expedia.com/Danville-Hotels-City-Express-By-Marriott-Danville.h1138194.Hotel-Information) ![OYO Hotel Durham West Hills](https://images.trvl-media.com/lodging/39000000/38430000/38422200/38422123/4d338daa_y.jpg) ### OYO Hotel Durham West Hills 6/10 Okay "You get what you pay for. Overall, wasnt horrible, a budget friendly place to stay for some sleep. Pictures from online are incredibly edited to look far more vibrant. Bed was about as hard as the floor. Looks like a revamped motel, and the area seems sketchy off a little side road. A few vending machines outside the main office. Closest place to eat is about 10 mins, limited options." [](https://expedia.com/Raleigh-Hotels-OYO-Hotel-Durham-Skyland.h38422123.Hotel-Information) ![Red Roof Inn Durham - Duke Univ Medical Center](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4b0fbe40_y.jpg) ### Red Roof Inn Durham - Duke Univ Medical Center 10/10 Excellent "Warren Buffett would approve of your smart decision to stay here. This is a safe, clean and economical place to stay, and close to everything. I appreciate the proprietors kindness and welcoming greeting. It’s a great value for your travel dollar. " [](https://expedia.com/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![The Bee Hotel Danville](https://images.trvl-media.com/lodging/61000000/60410000/60408600/60408544/2af5904e_y.jpg) ### The Bee Hotel Danville 10/10 Excellent "Excellence at it's best!!! Excellent accommodations, clean, spacious and inviting!!! Staff is top notch!! Kind, helpful, friendly people!!! I highly recommend this Gorgeous place!!!" [](https://expedia.com/Danville-Hotels-The-Bee-Hotel-Danville.h60408544.Hotel-Information) ![SureStay Plus Hotel by Best Western Durham Medical Center](https://images.trvl-media.com/lodging/1000000/20000/10500/10436/70510201_y.jpg) ### SureStay Plus Hotel by Best Western Durham Medical Center 8/10 Good "The staff is ok but they don’t really clean the room all the time" [](https://expedia.com/Raleigh-Hotels-Durham-Medical-Park-Inn-Suites.h10436.Hotel-Information) ![Hampton Inn Roxboro](https://images.trvl-media.com/lodging/1000000/160000/151400/151325/9c7dbd5a_y.jpg) ### Hampton Inn Roxboro 10/10 Excellent "Clean, large, quiet, comfortable room. Easy parking. Nice area. Great staff. Great breakfast." [](https://expedia.com/Roxboro-Hotels-Hampton-Inn-Roxboro.h151325.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Kirby Cultural Arts Complex ](https://www.expedia.com/Kirby-Cultural-Arts-Complex-Hotels.0-l6304513-0.Travel-Guide-Filter-Hotels) - [Hotels near Person County Museum ](https://www.expedia.com/Person-County-Museum-Hotels.0-l6304507-0.Travel-Guide-Filter-Hotels) - [Timberlake Hotels ](https://www.expedia.com/Timberlake-Hotels.d3000451005.Travel-Guide-Hotels) - [Cabin Rentals in Timberlake ](https://www.expedia.com/Timberlake-Cabins.d3000451005-aaCabins.Travel-Guide-Accommodation) - [5 Star Hotels in Timberlake ](https://www.expedia.com/5Star-Timberlake-Hotels.s50-0-d3000451005.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Timberlake ](https://www.expedia.com/4Star-Timberlake-Hotels.s40-0-d3000451005.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Timberlake ](https://www.expedia.com/3Star-Timberlake-Hotels.s30-0-d3000451005.Travel-Guide-Filter-Hotels) - 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