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Find hotels in Cherokee Seneca, Louisville

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Discover Cherokee Seneca hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

3.0 star property
4.4 mi from Cherokee Seneca
9.0 out of 10, Wonderful, (324)
"Very nice hotel and the staff "
United States
Denise
$98 nightly
The price is $115
Dec 14 - Dec 15
Total with taxes and fees
Courtyard by Marriott Louisville Airport
Lobby
Drury Inn & Suites Louisville East

Drury Inn & Suites Louisville East

3.0 star property
5.8 mi from Cherokee Seneca
9.4 out of 10, Exceptional, (1002)
"Always extremely clean, great staff and wonderful amenities!"
United States
Stephanie
$90 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Drury Inn & Suites Louisville East
Beach
Hilton Garden Inn Louisville/Northeast

Hilton Garden Inn Louisville/Northeast

3.0 star property
7.8 mi from Cherokee Seneca
9.0 out of 10, Wonderful, (223)
"Alway good!"
United States
Edward
$75 nightly
The price is $88
Dec 19 - Dec 20
Total with taxes and fees
Hilton Garden Inn Louisville/Northeast
Interior entrance
Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo

2.5 star property
2.3 mi from Cherokee Seneca
8.4 out of 10, Very Good, (1173)
"Very nice stop on out way to Wisconsin "
United States
Chuck
$65 nightly
The price is $76
Dec 28 - Dec 29
Total with taxes and fees
Wingate by Wyndham Louisville Fair and Expo
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4.0 star property
3.7 mi from Cherokee Seneca
9.4 out of 10, Exceptional, (1670)
"Clean rooms and front desk staff very pleasant."
United States
Kim
$119 nightly
The price is $140
Dec 8 - Dec 9
Total with taxes and fees
Derby City Gaming & Hotel - A Churchill Downs Property
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville, 3.9 mi from Cherokee Seneca
9.2 out of 10, Wonderful, (1707)
"Clean room, friendly staff"
United States
Jill
$167 nightly
The price is $197
Jan 1 - Jan 2, 2026
Total with taxes and fees
Omni Louisville Hotel
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville, 4.1 mi from Cherokee Seneca
9.0 out of 10, Wonderful, (3827)
"Beautiful room and great hospitality. "
United States
Chase
$133 nightly
The price is $157
Dec 16 - Dec 17
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
In-room safe, desk, blackout drapes, iron/ironing board
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

3.5 star property
Fairgrounds, 4.3 mi from Cherokee Seneca
8.8 out of 10, Excellent, (1017)
"Great place to stay!"
United States
Steven
$88 nightly
The price is $103
Dec 10 - Dec 11
Total with taxes and fees
Crowne Plaza Louisville Airport Expo Ctr by IHG
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

2.5 star property
Downtown Louisville, 4.4 mi from Cherokee Seneca
8.8 out of 10, Excellent, (1642)
"Nice room, walk in shower, great breakfast "
United States
Mark
$93 nightly
The price is $109
Dec 9 - Dec 10
Total with taxes and fees
Holiday Inn Express & Suites Louisville Downtown by IHG
Lobby
Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East

3.0 star property
St. Matthews, 3.2 mi from Cherokee Seneca
8.8 out of 10, Excellent, (1033)
"The room was very clean, check in was easy and staff was friendly and helpful."
United States
Melody
$99 nightly
The price is $116
Dec 21 - Dec 22
Total with taxes and fees
Hawthorn Suites by Wyndham Louisville East
Standard Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Microtel Inn by Wyndham Louisville East

Microtel Inn by Wyndham Louisville East

2.0 star property
Jeffersontown, 7.8 mi from Cherokee Seneca
6.8 out of 10, (1006)
"Clean, friendly, good breakfast"
United States
Aldo
$64 nightly
The price is $75
Dec 10 - Dec 11
Total with taxes and fees
Microtel Inn by Wyndham Louisville East
Exterior
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3.0 star property
7.6 mi from Cherokee Seneca
9.6 out of 10, Exceptional, (398)
"The staff was very friendly and helpful. The facility was clean, safe and well maintained. "
United States
Bianca
$103 nightly
The price is $117
Dec 14 - Dec 15
Total with taxes and fees
Hilton Garden Inn Jeffersonville Louisville North
Lobby
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

2.5 star property
11.5 mi from Cherokee Seneca
8.4 out of 10, Very Good, (1001)
"Clean room, helpful staff, good breakfast "
United States
Jessica
$72 nightly
The price is $82
Dec 9 - Dec 10
Total with taxes and fees
Ramada by Wyndham Sellersburg/Louisville North
Iron/ironing board, free WiFi, bed sheets
Staybridge Suites Louisville Expo Center by IHG

Staybridge Suites Louisville Expo Center by IHG

3.0 star property
Fairgrounds, 4.4 mi from Cherokee Seneca
9.2 out of 10, Wonderful, (489)
"Check in was great, staff is amazing and room had everything you could need."
United States
Jeffrey
$119 nightly
The price is $140
Jan 2 - Jan 3, 2026
Total with taxes and fees
Staybridge Suites Louisville Expo Center by IHG
Suite, 1 King Bed, Non Smoking | In-room safe, desk, iron/ironing board, free cribs/infant beds
Comfort Inn & Suites Louisville Airport Fair & Expo

Comfort Inn & Suites Louisville Airport Fair & Expo

2.5 star property
Fairgrounds, 4.3 mi from Cherokee Seneca
8.4 out of 10, Very Good, (134)
"Great place to stay! "
United States
Heather
$86 nightly
The price is $99
Dec 28 - Dec 29
Total with taxes and fees
Comfort Inn & Suites Louisville Airport Fair & Expo
Exterior
Hilton Garden Inn Louisville Airport

Hilton Garden Inn Louisville Airport

3.0 star property
Fairgrounds, 4.3 mi from Cherokee Seneca
9.0 out of 10, Wonderful, (1000)
"Hotel staff was friendly, cheerful and helpful from check-in to check-out. My favorite 2 day stay on a 31 day trip!"
United States
Richard
$87 nightly
The price is $102
Dec 27 - Dec 28
Total with taxes and fees
Hilton Garden Inn Louisville Airport
Lobby
Best Western Louisville Airport Expo

Best Western Louisville Airport Expo

2.5 star property
3.9 mi from Cherokee Seneca
8.6 out of 10, Excellent, (1000)
"Ecxellent hotel, will definitely stay again"
United States
Demchigsuren
$79 nightly
The price is $93
Dec 15 - Dec 16
Total with taxes and fees
Best Western Louisville Airport Expo
Exterior
Holiday Inn Louisville Airport South by IHG

Holiday Inn Louisville Airport South by IHG

3.0 star property
5.9 mi from Cherokee Seneca
8.8 out of 10, Excellent, (777)
"I've always had good luck with holiday inn. I have never encountered a dirty location. Rooms were comfortable, staff was friendly and breakfast was delicious. What more could you ask for? Oh, the location was a definite plus!"
United States
MaryLynn
$97 nightly
The price is $114
Jan 5 - Jan 6, 2026
Total with taxes and fees
Holiday Inn Louisville Airport South by IHG
Exterior
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

3.0 star property
10.7 mi from Cherokee Seneca
8.4 out of 10, Very Good, (917)
"Clean rooms, nice bar, and decent breakfast"
United States
Nathan
$82 nightly
The price is $97
Dec 14 - Dec 15
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
Exterior
Best Western Louisville South / Shepherdsville

Best Western Louisville South / Shepherdsville

2.5 star property
11.9 mi from Cherokee Seneca
8.6 out of 10, Excellent, (934)
"Nice place to stay great breakfast "
United States
Jessica
$80 nightly
The price is $89
Dec 11 - Dec 12
Total with taxes and fees
Best Western Louisville South / Shepherdsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas and neighborhoods for the activities you enjoy most.
Louisville showing signage and street scenes as well as a small group of people

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Bluegrass Indoor Karting and Jeffersontown Commons Shopping Center while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Conrad Caldwell House showing heritage elements and signage

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Top Cherokee Seneca Hotel Reviews

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

10/10 Excellent
"My room was spacious and the beds super comfortable. I loved the wall coverings throughout the property which portrayed much of rich history surrounding the Kentucky Derby."
Donna 2-night trip
Posted 15 hours ago
Derby City Gaming & Hotel - A Churchill Downs Property

Frequently asked questions

What are the best hotels in Cherokee Seneca that travelers recommend?
The Myriad Hotel in Louisville, KY, stands out as a top choice for travelers, boasting an exceptional score of 9.2. This hotel offers a unique blend of comfort and convenience, featuring an inviting outdoor pool complete with poolside cabanas and a bar, great for a relaxing day in the sun. Guests appreciate the stylishly designed rooms equipped with premium bedding and kitchenettes, allowing for a home-like experience during their stay.
What are the best family hotels in Cherokee Seneca?
The Myriad Hotel in Louisville, Kentucky, is an excellent choice for families seeking comfort and adventure during their travels. With a review score of 9.2, this hotel stands out for its friendly setting and family-friendly amenities.
What are the best budget hotels in Cherokee Seneca?
The Myriad Hotel in Louisville, KY, is a fantastic choice for travelers seeking comfort and convenience without breaking the bank. This hotel boasts a stellar rating of 9.2, indicating a high level of guest satisfaction. Families will appreciate the spacious outdoor pool area, complete with poolside cabanas and a bar, great for relaxing while the kids splash around.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Cherokee Seneca.
How can I save on a Cherokee Seneca hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Cherokee Seneca hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Cherokee Seneca hotel?
Hotel prices in Cherokee Seneca often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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