East Prairie, MO
Travel Guide
Visit East Prairie
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Sep 27 to Sep 28
$108 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,000 reviews)
"Great stay and friendly, nice staff! Loved it!"
Reviewed on Sep 15, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$66 nightly
The price is $76 total per night from Sep 20 to Sep 21
$76 total
Sep 20 - Sep 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Good place!"
Reviewed on Sep 16, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$87 nightly
The price is $99 total per night from Sep 20 to Sep 21
$99 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,005 reviews)
"Bathroom was not cleaned properly and there was no shower floor mat."
Reviewed on Sep 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (245 reviews)
"2nd stay here. Great relaxing place to stay. Very quite and peaceful area."
Reviewed on Sep 15, 2026
Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak TN
Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (36 reviews)
"Real foot refuge was a really nice place to stay , and they were really nice to work withWe are in Missouri, family.We had a really great time and wanting to do this again the neighbors were awesome, very friendly in kind.The real foot like visiting center.The pontoon ride was a very great experience.We ..."
Reviewed on Jul 4, 2026
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak TN
Stay at this vacation home in Hornbeak. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"
Reviewed on Jul 27, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular East Prairie attractions
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- Visit Cape Girardeau
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- Hunter-Dawson State Historic
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- Century Casino Caruthersville
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- Visit Bragg City
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- Bernie Vacations
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- Mid Size Car Rentals in Charleston
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- Car rental Airport (SIK)
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- Mississippi River
- Ohio River
- Reelfoot Lake State Park
- Discovery Park of America
- Reelfoot Lake
- Ohio River Valley
- Columbus-Belmont State Park
- Marston Community Center
- Union City Masquerade Theatre
- Central Park
- Fort Defiance State Park
- Graham Park
- New Madrid Historical Museum
- Hunter-Dawson State Historic Site
- Sikeston Depot Museum
- Campbell's Point
