Title: Visit Sikeston: 2026 Travel Guide for Sikeston, Missouri | Expedia.com [Hotels in Sikeston](https://expedia.com/Sikeston-Hotels.d6058766.Travel-Guide-Hotels)[Vacation Rentals in Sikeston](https://expedia.com/Sikeston-Vacation-Rentals.d6058766.Travel-Guide-VacationRentals)[Flights to Sikeston](https://expedia.com/Cheap-Flights-To-Sikeston.d6058766.Travel-Guide-Flights)[Car Rentals in Sikeston](https://expedia.com/Car-Rentals-In-Sikeston.d6058766.Car-Rental-Guide)[Sikeston Vacation Packages](https://expedia.com/Sikeston.d6058766.Destination-Travel-Guides) # Sikeston, MO ## Travel Guide ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Pre-teen girl walking through corn maze during fall](https://images.trvl-media.com/place/6058766/0353751e-5978-48d0-a913-84533caba2b0.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Columns and Dogwood Trees. Columns from an old church surrounded by colorful dog wood trees in full bloom ](https://images.trvl-media.com/place/6058766/eef79b9e-fdd7-4f80-86db-e7371463f21a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![The best restaurant I have EVER been to! Hands down!!!](https://images.trvl-media.com/place/553248634983441802/03fb167a-d590-4293-9dd9-648c99605c85.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Sikeston Things to do - Sikeston Hotel Deals - Vacation Rentals in Sikeston ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner Sikeston MO $90 nightly $103 total Feb 12 - Feb 13 Total with taxes and fees Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ... 9.4/10 Exceptional! (1,001 reviews) Great Reviewed on Feb 4, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F12%2F2026&endDate=2%2F13%2F2026&selected=24210&PinnedHotelID=24210&HadPinnedHotel=true®ionId=6058766) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Sikeston 1240 Commerce Drive Sikeston MO $96 nightly $109 total Feb 28 - Mar 1 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ... 8.8/10 Excellent! (474 reviews) Great place for an overnight stay. I will be back! Reviewed on Jan 26, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F28%2F2026&endDate=3%2F1%2F2026&selected=25178175&PinnedHotelID=25178175&HadPinnedHotel=true®ionId=6058766) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Sikeston 120 S Interstate Drive Sikeston MO $85 nightly $97 total Feb 22 - Feb 23 Total with taxes and fees Stay at this hotel in Sikeston. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. ... 8.2/10 Very Good! (1,001 reviews) Great breakfast. Clean room Quiet Reviewed on Jan 31, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F22%2F2026&endDate=2%2F23%2F2026&selected=8420572&PinnedHotelID=8420572&HadPinnedHotel=true®ionId=6058766) [See all 285 properties in Sikeston](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F9%2F2026&endDate=2%2F10%2F2026®ionId=6058766) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest](https://images.trvl-media.com/lodging/35000000/34340000/34332000/34331993/cb67aaf7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cabin in Southern Illinois - Hot Tub - Romantic Getaway -Shawnee National Forest Jonesboro IL Stay at this cabin in Jonesboro. Enjoy free WiFi, a garden, and patios. Popular attractions Grassy Lake and Union County State Fish and Wildlife Area are located ... 10/10 Exceptional! (197 reviews) Great place for a weekend getaway! Reviewed on Feb 3, 2026 [](https://expedia.com/Jonesboro-Hotels-Cabin-In-Southern-Illinois-Hot-Tub-Romantic-Getaway-Shawnee-National-Forest.h34331993.Hotel-Information) ![Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery ](https://images.trvl-media.com/lodging/75000000/74270000/74269700/74269659/47c539a2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery Cobden IL Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and in-room fireplaces. Popular attractions StarView Vineyards and King Neptune Memorial are ... 9.8/10 Exceptional! (155 reviews) Stayed there before, great spot, would stay again Reviewed on Jan 6, 2026 [](https://expedia.com/Anna-Hotels-Brand-New-Cabin-In-The-Woods-With-Hot-Tub-12-Mile-From-Starview-Winery.h74269659.Hotel-Information) ![Notting Hill Cottage](https://images.trvl-media.com/lodging/49000000/49000000/48991900/48991852/9fab7427_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Notting Hill Cottage Alto Pass IL Stay at this vacation home in Alto Pass. Enjoy laundry facilities, patios, and an in-room coffeemaker. Popular attractions Peachbarn Winery and Von Jakob Winery ... 9.6/10 Exceptional! (296 reviews) The house was perfect for our needs! this is the third time we have stayed there, and it never disappoints! Reviewed on Dec 2, 2025 [](https://expedia.com/Alto-Pass-Hotels-Notting-Hill-Cottage.h48991852.Hotel-Information) [See all properties in Sikeston](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6058766&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Sikeston hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2026-02-08&endDate=2026-02-09)[Feb 8 - Feb 9](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2026-02-08&endDate=2026-02-09) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2026-02-09&endDate=2026-02-10)[Feb 9 - Feb 10](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2026-02-09&endDate=2026-02-10) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026)[Feb 13 - Feb 15](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6058766&startDate=2%2F13%2F2026&endDate=2%2F15%2F2026) ### Popular places to visit #### City of Miner Convention Center Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this relaxing area, you can savor the top-notch restaurants. [](https://expedia.com/City-Of-Miner-Convention-Center-Sikeston.d818566100963352576.Vacation-Attraction) #### Sikeston Depot Museum 4/5(15 reviews) You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this relaxing area, you can savor the top-notch restaurants. [](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) #### Central Park 4/5(25 reviews) Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) ## Cities near Sikeston ![Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky. ](https://images.trvl-media.com/place/7182/2c4b1a06-d3aa-4171-b8b6-0e4eaaa0e80e.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Charleston ![Bridge over Mississippi River, New Orleans in background](https://images.trvl-media.com/place/6209928/57ec11c5-0aa9-4b04-9ae1-c121ec0bef56.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### East Prairie ### Other places like Sikeston ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Hotels near Sikeston Depot Museum ](https://www.expedia.com/Sikeston-Depot-Museum-Hotels.0-l6305602-0.Travel-Guide-Filter-Hotels) - [Hotels near Central Park ](https://www.expedia.com/Central-Park-Hotels.0-l6305608-0.Travel-Guide-Filter-Hotels) - [Hotels near Sikeston Memorial Municipal ](https://www.expedia.com/Sikeston-Memorial-Municipal-Airport-Hotels.0-aSIK-0.Travel-Guide-Filter-Hotels) - [Hotels near The Book Bug ](https://www.expedia.com/The-Book-Bug-Hotels.0-l553248621532655751-0.Travel-Guide-Filter-Hotels) - [Miner Hotels ](https://www.expedia.com/Miner-Hotels.d553248634983441802.Travel-Guide-Hotels) - [Bertrand Hotels ](https://www.expedia.com/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - [Motels in Bertrand ](https://www.expedia.com/Bertrand-Motels.d3000349285-aaMotels.Travel-Guide-Accommodation) - [4 Star Hotels in Bertrand ](https://www.expedia.com/4Star-Bertrand-Hotels.s40-0-d3000349285.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Bertrand ](https://www.expedia.com/3Star-Bertrand-Hotels.s30-0-d3000349285.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Bertrand ](https://www.expedia.com/5Star-Bertrand-Hotels.s50-0-d3000349285.Travel-Guide-Filter-Hotels) - [Matthews Hotels ](https://www.expedia.com/Matthews-Hotels.d553248634983428760.Travel-Guide-Hotels) - [Blodgett Hotels ](https://www.expedia.com/Blodgett-Hotels.d3000349291.Travel-Guide-Hotels) - [Canalou Hotels ](https://www.expedia.com/Canalou-Hotels.d3000349311.Travel-Guide-Hotels) - [Diehlstadt Hotels ](https://www.expedia.com/Diehlstadt-Hotels.d553248634983544913.Travel-Guide-Hotels) - [Morley Hotels ](https://www.expedia.com/Morley-Hotels.d553248634983172137.Travel-Guide-Hotels) - [East Prairie Hotels ](https://www.expedia.com/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels) - [Lodges in East Prairie ](https://www.expedia.com/East-Prairie-Lodges.d3000349349-aaLodges.Travel-Guide-Accommodation) - [Motels in East Prairie ](https://www.expedia.com/East-Prairie-Motels.d3000349349-aaMotels.Travel-Guide-Accommodation) - [Vacation Homes in East Prairie ](https://www.expedia.com/East-Prairie-Private-Vacation-Homes.d3000349349-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Charleston Hotels ](https://www.expedia.com/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Pet-friendly Hotels in Charleston ](https://www.expedia.com/Charleston-Hotels-Pet-Friendly-Hotel.0-0-d7182-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Charleston ](https://www.expedia.com/4Star-Charleston-Hotels.s40-0-d7182.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Charleston ](https://www.expedia.com/Charleston-Hotels-Cheap-Hotels.0-0-d7182-tCheapHotels.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Charleston ](https://www.expedia.com/Charleston-Hotels-Best-Western.0-0-d7182--bBestWestern.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Charleston ](https://www.expedia.com/Charleston-Hotels-Hotels-With-Restaurants.0-0-d7182-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Charleston ](https://www.expedia.com/Charleston-Hotels-Spa-Hotel.0-0-d7182-tSpaHotel.Travel-Guide-Filter-Hotels) - [Motels in Charleston ](https://www.expedia.com/Charleston-Motels.d7182-aaMotels.Travel-Guide-Accommodation) - [Palaces in Charleston ](https://www.expedia.com/Charleston-Palaces.d7182-aaPalaces.Travel-Guide-Accommodation) - [Hotels with a Pool in Charleston ](https://www.expedia.com/Charleston-Hotels-Hotel-With-Pool.0-0-d7182-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Charleston ](https://www.expedia.com/Charleston-Cabins.d7182-aaCabins.Travel-Guide-Accommodation) - [Historic Hotels in Charleston ](https://www.expedia.com/Charleston-Hotels-Historic-Hotel.0-0-d7182-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Waterpark Hotels in Charleston ](https://www.expedia.com/Charleston-Hotels-Waterpark-Hotels.0-0-d7182-tWaterparkHotels.Travel-Guide-Filter-Hotels) - [Oran Hotels ](https://www.expedia.com/Oran-Hotels.d3000445386.Travel-Guide-Hotels) - [Motels in Oran ](https://www.expedia.com/Oran-Motels.d3000445386-aaMotels.Travel-Guide-Accommodation) - [Apartments in Oran ](https://www.expedia.com/Oran-Apartments.d3000445386-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Oran ](https://www.expedia.com/Oran-Cabins.d3000445386-aaCabins.Travel-Guide-Accommodation) - [5 Star Hotels in Oran ](https://www.expedia.com/5Star-Oran-Hotels.s50-0-d3000445386.Travel-Guide-Filter-Hotels) - [Benton Hotels ](https://www.expedia.com/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Bell City Hotels ](https://www.expedia.com/Bell-City-Hotels.d553248634983588961.Travel-Guide-Hotels) - [Bloomfield Hotels ](https://www.expedia.com/Bloomfield-Hotels.d6351829.Travel-Guide-Hotels) - [Cabin Rentals in Bloomfield ](https://www.expedia.com/Bloomfield-Cabins.d6351829-aaCabins.Travel-Guide-Accommodation) - [Vacation Homes in Bloomfield ](https://www.expedia.com/Bloomfield-Private-Vacation-Homes.d6351829-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Motels in Bloomfield ](https://www.expedia.com/Bloomfield-Motels.d6351829-aaMotels.Travel-Guide-Accommodation) - [Flights from Sikeston Memorial Municipal ](https://www.expedia.com/lp/airports/sik/flights-from-sikeston-memorial-municipal-airport) - [Flights from Cape Girardeau (CGI) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/cgi/sik/cape-girardeau-to-sikeston) - [Flights from Nashville (BNA) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/bna/sik/nashville-to-sikeston) - [Flights from Houston (IAH) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/iah/sik/houston-to-sikeston) - [Flights from Chicago (ORD) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/ord/sik/chicago-to-sikeston) - [Flights from Dallas (DFW) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/dfw/sik/dallas-to-sikeston) - [Flights from Minneapolis (MSP) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/msp/sik/minneapolis-to-sikeston) - [Flights from Detroit (DTW) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/dtw/sik/detroit-to-sikeston) - [Flights from Orlando (MCO) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/mco/sik/orlando-to-sikeston) - [Flights from New Orleans (MSY) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/msy/sik/new-orleans-to-sikeston) - [Flights from Los Angeles (LAX) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/lax/sik/los-angeles-to-sikeston) - [Flights from Bowling Green (BWG) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/bwg/sik/bowling-green-to-sikeston) - [Flights from Philadelphia (PHL) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/phl/sik/philadelphia-to-sikeston) - [Flights from New York (NYC) to Sikeston (SIK) ](https://www.expedia.com/lp/flights/nyc/sik/new-york-to-sikeston) - [Flights from Morehouse ](https://www.expedia.com/lp/flights/553248634983462037/flights-from-morehouse) - [Flights to Bertrand ](https://www.expedia.com/Cheap-Flights-To-Bertrand.d3000349285.Travel-Guide-Flights) - [Flights from Bertrand ](https://www.expedia.com/lp/flights/3000349285/flights-from-bertrand) - [Flights from Blodgett ](https://www.expedia.com/lp/flights/3000349291/flights-from-blodgett) - [Flights from Morley ](https://www.expedia.com/lp/flights/553248634983172137/flights-from-morley) - [Flights from East Prairie ](https://www.expedia.com/lp/flights/3000349349/flights-from-east-prairie) - [Flights to Charleston ](https://www.expedia.com/Cheap-Flights-To-Charleston.d7182.Travel-Guide-Flights) - [Flights from Charleston ](https://www.expedia.com/lp/flights/7182/flights-from-charleston) - [Flights to Oran ](https://www.expedia.com/Cheap-Flights-To-Oran.d3000445386.Travel-Guide-Flights) - [Flights to Bloomfield ](https://www.expedia.com/Cheap-Flights-To-Bloomfield.d6351829.Travel-Guide-Flights) - [Flights from Stoddard County ](https://www.expedia.com/lp/flights/553248635976432323/flights-from-stoddard-county) - [Sikeston Depot Museum ](https://www.expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Central Park ](https://www.expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Boot Heel Golf Club ](https://www.expedia.com/Boot-Heel-Golf-Club-Sikeston.d6305606.Vacation-Attraction) - [Visit Bertrand ](https://www.expedia.com/Bertrand.dx3000349285) - [Bertrand Vacations ](https://www.expedia.com/Bertrand.d3000349285.Destination-Travel-Guides) - [Visit Blodgett ](https://www.expedia.com/Blodgett.dx3000349291) - [Visit Canalou ](https://www.expedia.com/Canalou.dx3000349311) - [Visit East Prairie ](https://www.expedia.com/East-Prairie.dx3000349349) - [Charleston Vacations ](https://www.expedia.com/Charleston.d7182.Destination-Travel-Guides) - [Visit Oran ](https://www.expedia.com/Oran.dx3000445386) - [Bloomfield Vacations ](https://www.expedia.com/Bloomfield.d6351829.Destination-Travel-Guides) - [Visit Catron ](https://www.expedia.com/Catron.dx3000349317) - [Car rentals near The Book Bug ](https://www.expedia.com/Car-Rentals-In-The-Book-Bug.d553248621532655751.Car-Rental-Guide) - [Car rentals near Miner ](https://www.expedia.com/Car-Rentals-In-Miner.d553248634983441802.Car-Rental-Guide) - [Dollar Europe Rental Cars in Miner ](https://www.expedia.com/Dollar-Europe-Car-Rentals-In-Miner.d553248634983441802-c1090.Car-Rental-Guide-Suppliers) - [Car rentals near Bertrand ](https://www.expedia.com/Car-Rentals-In-Bertrand.d3000349285.Car-Rental-Guide) - [Car rentals near Blodgett ](https://www.expedia.com/Car-Rentals-In-Blodgett.d3000349291.Car-Rental-Guide) - [Car rentals near Canalou ](https://www.expedia.com/Car-Rentals-In-Canalou.d3000349311.Car-Rental-Guide) - [Car rentals near Baker ](https://www.expedia.com/Car-Rentals-In-Baker.d553248634983252914.Car-Rental-Guide) - [Car rentals near East Prairie ](https://www.expedia.com/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide) - [Car rentals near Charleston ](https://www.expedia.com/Car-Rentals-In-Charleston.d7182.Car-Rental-Guide) - [Payless Rental Cars in Charleston ](https://www.expedia.com/Payless-Car-Rentals-In-Charleston.d7182-c38.Car-Rental-Guide-Suppliers) - [Goldcar rental Rental Cars in Charleston ](https://www.expedia.com/Goldcar-Rental-Car-Rentals-In-Charleston.d7182-c1022.Car-Rental-Guide-Suppliers) - [Car rentals near Oran ](https://www.expedia.com/Car-Rentals-In-Oran.d3000445386.Car-Rental-Guide) - [Car rentals near Benton ](https://www.expedia.com/Car-Rentals-In-Benton.d553248634983369680.Car-Rental-Guide) - [Car rentals near Essex ](https://www.expedia.com/Car-Rentals-In-Essex.d553248634983169000.Car-Rental-Guide) - [Car rentals near Bloomfield ](https://www.expedia.com/Car-Rentals-In-Bloomfield.d6351829.Car-Rental-Guide) - [Blodgett Vacation Rentals ](https://www.expedia.com/Blodgett-Vacation-Rentals.d3000349291.Travel-Guide-VacationRentals) - [East Prairie Vacation Rentals ](https://www.expedia.com/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals) - [Charleston Vacation Rentals ](https://www.expedia.com/Charleston-Vacation-Rentals.d7182.Travel-Guide-VacationRentals) - [Oran Vacation Rentals ](https://www.expedia.com/Oran-Vacation-Rentals.d3000445386.Travel-Guide-VacationRentals) - [Bloomfield Vacation Rentals ](https://www.expedia.com/Bloomfield-Vacation-Rentals.d6351829.Travel-Guide-VacationRentals) - Cities near Sikeston - Places of interest [Charleston](https://expedia.com/Charleston.dx7182)[Bertrand](https://expedia.com/Bertrand.dx3000349285)[Blodgett](https://expedia.com/Blodgett.dx3000349291)[Canalou](https://expedia.com/Canalou.dx3000349311)[East Prairie](https://expedia.com/East-Prairie.dx3000349349)[Oran](https://expedia.com/Oran.dx3000445386) - [Sikeston Depot Museum ](https://expedia.com/Sikeston-Depot-Museum-Sikeston.d6305602.Vacation-Attraction) - [Central Park ](https://expedia.com/Central-Park-Sikeston.d6305608.Vacation-Attraction) - [Mississippi River ](https://expedia.com/Mississippi-River-United-States-of-America.d6209928.Vacation-Attraction) - [Shawnee National Forest ](https://expedia.com/Shawnee-National-Forest-Illinois.d553248635944113522.Vacation-Attraction) - [Ohio River ](https://expedia.com/Ohio-River-United-States-of-America.d681940626945888256.Vacation-Attraction) - [Southeast Missouri State University ](https://expedia.com/Southeast-Missouri-State-University-Cape-Girardeau.d553248621554122994.Vacation-Attraction) - [Ohio River Valley ](https://expedia.com/Ohio-River-Valley-United-States-of-America.d6233674.Vacation-Attraction) - [Riverfront Park ](https://expedia.com/Riverfront-Park-Cape-Girardeau.d740677735274594304.Vacation-Attraction) - [Riverfront Bridge Park ](https://expedia.com/Riverfront-Bridge-Park-Cape-Girardeau.d553248621532655774.Vacation-Attraction) - [eDen Spa & Salon ](https://expedia.com/EDen-Spa-Salon-Cape-Girardeau.d553248621532655776.Vacation-Attraction) - [New Madrid Historical Museum ](https://expedia.com/New-Madrid-Historical-Museum-New-Madrid.d553248621532655748.Vacation-Attraction) - [Marston Community Center ](https://expedia.com/Marston-Community-Center-Marston.d553248622945532712.Vacation-Attraction) - [Mound City National Cemetery ](https://expedia.com/Mound-City-National-Cemetery-Mound-City.d553248621555594730.Vacation-Attraction) - [The Heritage House ](https://expedia.com/The-Heritage-House-Dexter.d553248621592342444.Vacation-Attraction) - [Dexter Welcome Center Depot and Museum ](https://expedia.com/Dexter-Welcome-Center-Depot-And-Museum-Dexter.d553248621592342445.Vacation-Attraction) - [Fort Defiance State Park ](https://expedia.com/Fort-Defiance-State-Park-Cairo.d6091411.Vacation-Attraction) - [Stoddard County Civil War Memorial Cemetery ](https://expedia.com/Stoddard-County-Civil-War-Memorial-Cemetery-Dexter.d553248621532655747.Vacation-Attraction) - [Hunter-Dawson State Historic Site ](https://expedia.com/Hunter-Dawson-State-Historic-Site-New-Madrid.d553248621532655794.Vacation-Attraction) - [Fort D Historic Site ](https://expedia.com/Fort-D-Historic-Site-Cape-Girardeau.d553248621532655775.Vacation-Attraction)