Sikeston, MO
Travel Guide
Visit Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$111 nightly
The price is $128 total per night from Jul 1 to Jul 2
$128 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
"This was a wonderful stay for the night while traveling. Thankful for the recommendation from the front desk to eat at Lamberts restaurant 3 minutes down the road. So fun!"
Reviewed on Jun 15, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$68 nightly
The price is $78 total per night from Jul 13 to Jul 14
$78 total
Jul 13 - Jul 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,001 reviews)
"Rooms are nice and clean although fixtures could be updated. There is no central air and heat, room is cooled by a wall unit. Room was extremely hot when I first entered."
Reviewed on Jun 24, 2026
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$102 nightly
The price is $115 total per night from Jul 12 to Jul 13
$115 total
Jul 12 - Jul 13
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (580 reviews)
"Enjoyed my stay very clean and comfortable"
Reviewed on Jun 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
New cabin in the woods with private hot tub
Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and air conditioning. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (155 reviews)
"Definitely will be back"
Reviewed on May 31, 2026
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Cobden IL
Stay at this cabin in Anna. Enjoy patios, an in-room coffeemaker, and in-room fireplaces. Popular attractions StarView Vineyards and King Neptune Memorial are ...
10/10 Exceptional! (169 reviews)
"Nice quiet place to stay, very close to the star view winery. 20 minutes from the Giant City lodge and Bald Knob Cross"
Reviewed on Jun 7, 2026
Cozy and Updated Farmhouse with King Suite
Anna IL
Stay at this vacation home in Anna. Enjoy free WiFi, laundry facilities, and patios. Popular attractions Anna City Park and Lincoln Heritage Winery are located ...
9.8/10 Exceptional! (20 reviews)
"The good: Communication with the host was excellent throughout the whole process! The beds and couches were very comfortable and there were plenty of towels and pillows. The inside of the house was very clean. The value we got for the money was incredible!The bad: Upon arrival, there was a lot of ..."
Reviewed on Jun 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Sikeston Depot Museum
4/5(15 reviews)
You can spend time exploring the galleries in Sikeston Depot Museum in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.
Central Park
4/5(25 reviews)
Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savor the top-notch restaurants.
City of Miner Convention Center
Learn about the events happening at City of Miner Convention Center during your trip to Miner. While in this family-friendly area, you can savor the top-notch restaurants.
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- Sikeston Depot Museum
- Central Park
- Mississippi River
- Shawnee National Forest
- Ohio River
- Ohio River Valley
- Southeast Missouri State University
- Riverfront Bridge Park
- Riverfront Park
- eDen Spa & Salon
- Dexter Welcome Center Depot and Museum
- The Heritage House
- Mound City National Cemetery
- Stoddard County Civil War Memorial Cemetery
- Fort Defiance State Park
- Marston Community Center
- New Madrid Historical Museum
- Hunter-Dawson State Historic Site
- Fort D Historic Site
