Title: Florence Vacation Packages 2026 from $413 | Expedia.com [Florence Travel Guide](https://expedia.com/Florence.dx1221)[Hotels in Florence](https://expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels)[Vacation Rentals in Florence](https://expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Things to do in Florence](https://expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities)[Car Rentals in Florence](https://expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Florence Vacations from $413 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Florence Vacation With a Florence vacation package, say goodbye to travel planning and hello to an effortless adventure. Every detail of your escape has been taken care of before you go, so you can get on with experiencing this awesome city. If your trip to Florence includes some sightseeing, hit up well-known attractions like [Florence Civic Center](https://www.expedia.com/Florence-Civic-Center-Florence.d6165605.Vacation-Attraction), [Magnolia Mall](https://www.expedia.com/Magnolia-Mall-Florence.d6165602.Vacation-Attraction) and [Florence National Cemetery](https://www.expedia.com/Florence-National-Cemetery-Florence.d553248621532657341.Vacation-Attraction). Check out Expedia's wide range of travel options and start organizing your perfect vacation to Florence today. ## The Latest Florence vacation packages Price found within the past 48 hours. Click for updated prices. ![Americas Best Value Inn Bishopville](https://images.trvl-media.com/lodging/1000000/30000/27700/27650/26fb3d06_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Americas Best Value Inn Bishopville $413 per person Apr 14 - Apr 18 found 2 hours ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Florence (FLO) 7.2/10 Good! (89 reviews) The room smelled clean, looked clean and I found no bed bugs. To look at it, we were not sure about our choice. But the wife and I were very pleased. If in the area, we will definitely stay there again. Reviewed on Oct 27, 2025 ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Comfort Inn & Suites Florence Center Area $729 per person Mar 13 - Mar 17 found 1 day ago Roundtrip non-stop flight included Manchester (MHT) to Florence (FLO) 9.2/10 Wonderful! (1,145 reviews) Staff was excellent!! Clean rooms, bed was so comfortable! Quiet all night. Reviewed on Feb 4, 2026 ![Affordable Suites Florence](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/7895bf64_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Affordable Suites Florence $583 per person Mar 13 - Mar 17 found 1 day ago Roundtrip non-stop flight included Manchester (MHT) to Florence (FLO) 9.2/10 Wonderful! (120 reviews) Nice clean room; friendly staff Reviewed on Jan 11, 2026 ![Quality Inn Mullins - Marion](https://images.trvl-media.com/lodging/1000000/30000/24900/24816/618b4a3e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Quality Inn Mullins - Marion $648 per person Mar 13 - Mar 17 found 1 day ago Roundtrip non-stop flight included Manchester (MHT) to Florence (FLO) 7.6/10 Good! (369 reviews) Overall stay was good, they didn't have our reservations request which was given during booking. Reviewed on Jan 24, 2026 ![The Mantissa Hotel](https://images.trvl-media.com/lodging/16000000/15720000/15719100/15719033/39339da9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Mantissa Hotel $823 per person Mar 13 - Mar 17 found 1 day ago Roundtrip non-stop flight included Manchester (MHT) to Florence (FLO) 9.2/10 Wonderful! (268 reviews) Excellent and accommodating staff. Great and spacious room. We would definitely return. Reviewed on Nov 23, 2025 Don't see what you're looking for? See all available trips from Columbus to Florence [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-08/2026-03-15/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=DLL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ### Discover the most popular places to visit in Florence ![Florence_FlorenceCivicCenter_6165605_0005](https://images.trvl-media.com/place/6165605/469ba674-c82b-48e7-81cb-5533222130a5.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Civic Center After visiting Florence Civic Center, make a plan to see the other sights and activities in Florence. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Florence-Civic-Center-Florence.d6165605.Vacation-Attraction) ![Florence_MagnoliaMall_6165602_0005](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Magnolia Mall You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this family-friendly area, you can savor the top-notch restaurants. [](https://expedia.com/Magnolia-Mall-Florence.d6165602.Vacation-Attraction) ![Florence_McleodRegionalMedicalCenter_6162127_0006](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Mcleod Regional Medical Center Though Mcleod Regional Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Florence while you are here. [](https://expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) ## Florence Hotel Deals ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Park Inn by Radisson Florence, SC 1729 Mandeville Road Florence SC Fully refundable $85 nightly $95 total Feb 15 - Feb 16 Total with taxes and fees 8.8/10 Excellent! (2,252 reviews) Clean nice and modern Reviewed on Feb 3, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F15%2F2026&endDate=2%2F16%2F2026&selected=47086732&PinnedHotelID=47086732&HadPinnedHotel=true®ionId=1221) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Howard Johnson by Wyndham Florence 2038 W Lucas Street Florence SC Fully refundableReserve now, pay when you stay $70 nightly $79 total Feb 9 - Feb 10 Total with taxes and fees 8.6/10 Excellent! (2,570 reviews) Always clean, 3rd time staying heading South. Breakfast is sufficient for busy travelers. Reviewed on Feb 7, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F9%2F2026&endDate=2%2F10%2F2026&selected=11037&PinnedHotelID=11037&HadPinnedHotel=true®ionId=1221) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn & Suites Florence Center Area 527 Woody Jones Blvd Florence SC Fully refundableReserve now, pay when you stay $82 nightly $91 total Feb 15 - Feb 16 Total with taxes and fees 9/10 Wonderful! (1,216 reviews) room was very clean, staff was very pleasant and easy to work with. I would recommend this place for sure, and look forward to staying there again Reviewed on Feb 4, 2026 [](https://expedia.com/Hotel-Search?startDate=2%2F15%2F2026&endDate=2%2F16%2F2026&selected=38336321&PinnedHotelID=38336321&HadPinnedHotel=true®ionId=1221) [See all 375 properties in Florence](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F9%2F2026&endDate=2%2F10%2F2026®ionId=1221) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Florence Vacation Packages ## Florence Essential Information | Language | English | | --------------- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Closest Airport | Florence Regional Airport (FLO) | | Population | 38,200 | | Max Temp Winter | 55ºF | | Max Temp Summer | 90ºF | | Top Sights | [Florence Museum](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction), [Florence Civic Center](https://www.expedia.com/Florence-Civic-Center-Florence.d6165605.Vacation-Attraction) and [Florence Motor Speedway](https://www.expedia.com/Florence-Motor-Speedway-Timmonsville.d6215468.Vacation-Attraction) | ## More vacations 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Choose the perfect time to travel: Your schedule, favorite season and the type of weather you enjoy can all influence your decision on when to visit Florence. > 2. Work out your budget: Ensure you have enough money to cover everything from transportation and meals to activities and airfares. Your accommodations will probably be the biggest expense during your trip to Florence. > 3. Use Expedia's [trip planning tool](https://www.expedia.com/why/trip-planning) to discover Florence: Research every part of your trip to Florence with this handy planner. Invite your friends and family to collaborate on a group trip, search for stays or things to do and make bookings. > 4. Work out your trip length: Think about how long you'd like to spend exploring Florence. Plan your itinerary so you can get to all the activities and attractions you're interested in at a leisurely pace. > 5. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a tailored Florence vacation package. > 6. Book experiences or activities ahead of time: Whether it's a ticket to a major attraction or a walking tour, you won't have to worry about missing out on the highlights of Florence. Find all the fun [things to do in Florence](https://www.expedia.com/Things-To-Do-In-Florence.d1221.Travel-Guide-Activities) with our dedicated travel guide. ### Does Expedia offer Book Now, Pay Later Florence vacation packages? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Regional ](https://www.expedia.com/Florence-Regional-Airport-Hotels.0-aFLO-0.Travel-Guide-Filter-Hotels) - [Flights from Florence Regional ](https://www.expedia.com/lp/airports/flo/flights-from-florence-regional-airport) - 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[Flights from Seattle (SEA) to Florence (FLO) ](https://www.expedia.com/lp/flights/sea/flo/seattle-to-florence) - [Flights from Pittsburgh (PIT) to Florence (FLO) ](https://www.expedia.com/lp/flights/pit/flo/pittsburgh-to-florence) - [Flights from Detroit (DTW) to Florence (FLO) ](https://www.expedia.com/lp/flights/dtw/flo/detroit-to-florence) - [Flights from Albany (ALB) to Florence (FLO) ](https://www.expedia.com/lp/flights/alb/flo/albany-to-florence) - [Flights from Buffalo (BUF) to Florence (FLO) ](https://www.expedia.com/lp/flights/buf/flo/buffalo-to-florence) - [Flights from Lexington (LEX) to Florence (FLO) ](https://www.expedia.com/lp/flights/lex/flo/lexington-to-florence) - [Flights from Louisville (SDF) to Florence (FLO) ](https://www.expedia.com/lp/flights/sdf/flo/louisville-to-florence) - [Flights from Cleveland (CLE) to Florence (FLO) ](https://www.expedia.com/lp/flights/cle/flo/cleveland-to-florence) - [Flights from Austin (AUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/aus/flo/austin-to-florence) - [Flights from San Francisco (SFO) to Florence (FLO) ](https://www.expedia.com/lp/flights/sfo/flo/san-francisco-to-florence) - [Flights from Greensboro (GSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/gso/flo/greensboro-to-florence) - [Flights from Columbus (CMH) to Florence (FLO) ](https://www.expedia.com/lp/flights/cmh/flo/columbus-to-florence) - [Flights from Richmond (RIC) to Florence (FLO) ](https://www.expedia.com/lp/flights/ric/flo/richmond-to-florence) - [Flights from Augusta (AGS) to Florence (FLO) ](https://www.expedia.com/lp/flights/ags/flo/augusta-to-florence) - [Flights from Tucson (TUS) to Florence (FLO) ](https://www.expedia.com/lp/flights/tus/flo/tucson-to-florence) - [Flights from Birmingham (BHM) to Florence (FLO) ](https://www.expedia.com/lp/flights/bhm/flo/birmingham-to-florence) - [Flights from Syracuse (SYR) to Florence (FLO) ](https://www.expedia.com/lp/flights/syr/flo/syracuse-to-florence) - [Flights from Chattanooga (CHA) to Florence (FLO) ](https://www.expedia.com/lp/flights/cha/flo/chattanooga-to-florence) - 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[Flights from Milwaukee (MKE) to Florence (FLO) ](https://www.expedia.com/lp/flights/mke/flo/milwaukee-to-florence) - [Flights from Sacramento (SMF) to Florence (FLO) ](https://www.expedia.com/lp/flights/smf/flo/sacramento-to-florence) - [Flights from Colorado Springs (COS) to Florence (FLO) ](https://www.expedia.com/lp/flights/cos/flo/colorado-springs-to-florence) - [Flights from Kansas City (MCI) to Florence (FLO) ](https://www.expedia.com/lp/flights/mci/flo/kansas-city-to-florence) - [Flights from Providence (PVD) to Florence (FLO) ](https://www.expedia.com/lp/flights/pvd/flo/providence-to-florence) - [Flights from El Paso (ELP) to Florence (FLO) ](https://www.expedia.com/lp/flights/elp/flo/el-paso-to-florence) - [Flights from Cincinnati (CVG) to Florence (FLO) ](https://www.expedia.com/lp/flights/cvg/flo/cincinnati-to-florence) - [Flights from West Palm Beach (PBI) to Florence (FLO) ](https://www.expedia.com/lp/flights/pbi/flo/west-palm-beach-to-florence) - [Flights from New Orleans (MSY) to Florence (FLO) ](https://www.expedia.com/lp/flights/msy/flo/new-orleans-to-florence) - [Flights from Asheville (AVL) to Florence (FLO) ](https://www.expedia.com/lp/flights/avl/flo/asheville-to-florence) - [Flights from Gainesville (GNV) to Florence (FLO) ](https://www.expedia.com/lp/flights/gnv/flo/gainesville-to-florence) - [Flights from Missoula (MSO) to Florence (FLO) ](https://www.expedia.com/lp/flights/mso/flo/missoula-to-florence) - [Flights from Lancaster (LNS) to Florence (FLO) ](https://www.expedia.com/lp/flights/lns/flo/lancaster-to-florence) - [Flights from Nairobi (NBO) to Florence (FLO) ](https://www.expedia.com/lp/flights/nbo/flo/nairobi-to-florence) - [Flights from New Haven (HVN) to Florence (FLO) ](https://www.expedia.com/lp/flights/hvn/flo/new-haven-to-florence) - [Flights from Tallahassee (TLH) to Florence (FLO) ](https://www.expedia.com/lp/flights/tlh/flo/tallahassee-to-florence) - [Flights from Harrisburg (MDT) to Florence (FLO) ](https://www.expedia.com/lp/flights/mdt/flo/harrisburg-to-florence) - [Flights from Washington (IAD) to Florence (FLO) ](https://www.expedia.com/lp/flights/iad/flo/washington-to-florence) - [Flights from Boise (BOI) to Florence (FLO) ](https://www.expedia.com/lp/flights/boi/flo/boise-to-florence) - [Flights from Allentown (ABE) to Florence (FLO) ](https://www.expedia.com/lp/flights/abe/flo/allentown-to-florence) - [Flights from Salt Lake City (SLC) to Florence (FLO) ](https://www.expedia.com/lp/flights/slc/flo/salt-lake-city-to-florence) - [Flights from Montgomery (MGM) to Florence (FLO) ](https://www.expedia.com/lp/flights/mgm/flo/montgomery-to-florence) - [Flights from Eugene (EUG) to Florence (FLO) ](https://www.expedia.com/lp/flights/eug/flo/eugene-to-florence) - [Flights from Fayetteville (FAY) to Florence (FLO) ](https://www.expedia.com/lp/flights/fay/flo/fayetteville-to-florence) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - 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