This is a tough one ... the hotel itself was perfectly nice. Up until my last morning there, my only complaint would have been that the hotel was a bit noisy due to its location and less than ideal insulation. The hotel was clean, had a very comfortable bed, a good shower, and was very convenient to the subway and metrobus. However, the final morning there, my boyfriend and I were awoken by the sound of many, many gunshots nearby. While this didn't sound like a gun battle--more like someone just firing a gun repeatedly at length--it was very unnerving, and needless to say caused us to cancel our plan to take the subway to the airport, as we had no intention of going out in the street. The person working at the front desk kindly called us a cab, which we were able to enter from the hotel's garage and so didn't need to go outside.
I feel a bit bad dinging the hotel for something that's so obviously not their fault, but at the same time, I feel like other travelers will want to know. I did look up the general safety of Mexico City neighborhoods before booking the hotel, and this neighborhood was not mentioned as being any less safe than others.