$145 Cheap Flights from Buffalo (BUF) to Santo Domingo (SDQ)

View $145 flight on Tue, Feb 3, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo

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Cheap Flights from Buffalo to Santo Domingo (BUF-SDQ)

Prices were available within the past 7 days and start at $145 for one-way flights and $310 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Tue, Feb 17 - Wed, Feb 18
BUF
Buffalo
SDQ
Santo Domingo
$310 Roundtrip, found 10 hours ago
$310
Roundtrip
found 10 hours ago
Select JetBlue Airways flight, departing Tue, Feb 17 from Buffalo to Santo Domingo, returning Wed, Feb 18, priced at $310 found 10 hours ago
JetBlue Airways
Mon, May 4 - Tue, May 5
BUF
Buffalo
SDQ
Santo Domingo
$311 Roundtrip, found 2 days ago
$311
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, May 4 from Buffalo to Santo Domingo, returning Tue, May 5, priced at $311 found 2 days ago
American Airlines
Tue, Jan 20 - Sat, Jan 24
BUF
Buffalo
SDQ
Santo Domingo
$318 Roundtrip, found 8 hours ago
$318
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Jan 20 from Buffalo to Santo Domingo, returning Sat, Jan 24, priced at $318 found 8 hours ago
American Airlines
Tue, Feb 3 - Mon, Feb 9
BUF
Buffalo
SDQ
Santo Domingo
$318 Roundtrip, found 1 hour ago
$318
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Tue, Feb 3 from Buffalo to Santo Domingo, returning Mon, Feb 9, priced at $318 found 1 hour ago
American Airlines
Wed, Jan 21 - Sat, Jan 24
BUF
Buffalo
SDQ
Santo Domingo
$320 Roundtrip, found 8 hours ago
$320
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Wed, Jan 21 from Buffalo to Santo Domingo, returning Sat, Jan 24, priced at $320 found 8 hours ago
American Airlines
Fri, Jan 23 - Sun, Feb 1
BUF
Buffalo
SDQ
Santo Domingo
$323 Roundtrip, found 15 hours ago
$323
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Fri, Jan 23 from Buffalo to Santo Domingo, returning Sun, Feb 1, priced at $323 found 15 hours ago
American Airlines
Sat, Mar 14 - Thu, Mar 19
BUF
Buffalo
SDQ
Santo Domingo
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Mar 14 from Buffalo to Santo Domingo, returning Thu, Mar 19, priced at $324 found 1 day ago
Frontier Airlines
Sat, Jan 10 - Sat, Jan 24
BUF
Buffalo
SDQ
Santo Domingo
$327 Roundtrip, found 4 days ago
$327
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Jan 10 from Buffalo to Santo Domingo, returning Sat, Jan 24, priced at $327 found 4 days ago
Delta
Mon, Feb 2 - Fri, Feb 13
BUF
Buffalo
SDQ
Santo Domingo
$328 Roundtrip, found 3 hours ago
$328
Roundtrip
found 3 hours ago
Select Delta flight, departing Mon, Feb 2 from Buffalo to Santo Domingo, returning Fri, Feb 13, priced at $328 found 3 hours ago
United
Thu, Jan 22 - Wed, Jan 28
BUF
Buffalo
SDQ
Santo Domingo
$332 Roundtrip, found 12 hours ago
$332
Roundtrip
found 12 hours ago
Select United flight, departing Thu, Jan 22 from Buffalo to Santo Domingo, returning Wed, Jan 28, priced at $332 found 12 hours ago

Find the cheapest month to fly from Buffalo (BUF) to Santo Domingo (SDQ)

October is typically the cheapest month to fly

From $318 - $508 per traveler.

Alternative airports near Santo Domingo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Las Americas Intl. SDQ. Cheapest option available. Average driving time to city center is 22 minutes. Flights from $437
SDQ
Las Americas Intl.
Cheapest
Average driving time to city center22 min
Flights from $437

Frequently asked questions

How much does a flight from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ) cost?
Lock in a cheap one-way flight from $145 or cheap return flight from $310 from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ)?
Planning your getaway for February can help you save, as it's the cheapest month for flights between BUF and SDQ. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest BUF to SDQ flight.
How many flights per day from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ)?
You'll need to take a flight with a layover if you're traveling from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ). There are no daily direct flights on this route. However, simply filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from BUF to SDQ?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ)?
Book a flight from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ) that takes off before 3 PM to reduce the risk of cancellations and delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ) last-minute?
Booking your plane ticket from BUF to SDQ just before your journey is typically more expensive. However, if you're flexible with your departure times and dates, you could snag a cheap last-minute fare.
Is it cheaper to book a BUF to SDQ flight and hotel package?
You can save money by securing a BUF to SDQ flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred flights and accommodations, you can add extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Buffalo Niagara Intl. Airport (BUF) to Las Americas Intl. Airport (SDQ)?
In most instances, you can modify or cancel your BUF to SDQ flight. However, additional charges may apply, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's fees and policies on flight changes, or if you need more information, go to our Customer Service portal.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Las Americas Intl.
Airlines serving
American Airlines, Copa, Delta, Frontier Airlines, JetBlue Airways, United
Roundtrip price
$309
Distance
1773 mi

Book with confidence

Buffalo to Santo Domingo Flights

The cheapest times to fly from Buffalo to Santo Domingo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Buffalo to Santo Domingo are during the month of February. You can find some of the cheapest flights from Buffalo to Santo Domingo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Buffalo to Santo Domingo

Sunday is one of the best days to book for cheap flights from Buffalo to Santo Domingo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Buffalo to Santo Domingo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Buffalo to Santo Domingo in 2026. You can also book with separate airlines for your outbound and return journeys, from $145 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Buffalo to Santo Domingo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Buffalo to Santo Domingo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Buffalo to Santo Domingo Flights

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*Available to One Key members.